NTDB

Overview

Name	endA	Type	Machinery gene
Locus tag	GE022_RS06040	Genome accession	NZ_CP053790
Coordinates	1241046..1241912 (-)	Length	288 a.a.
NCBI ID	WP_003047901.1	Uniprot ID	A0AAV3FR50
Organism	Streptococcus canis strain HL_77_2
Function	cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1236046..1246912

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE022_RS06020 (GE022_006010)	-	1236118..1236294 (-)	177	Protein_1141	IS3 family transposase	-
GE022_RS11005	-	1236274..1236566 (+)	293	Protein_1142	integrase core domain-containing protein	-
GE022_RS06030 (GE022_006020)	pheT	1236601..1239006 (-)	2406	WP_164405815.1	phenylalanine--tRNA ligase subunit beta	-
GE022_RS06035 (GE022_006025)	pheS	1239720..1240763 (-)	1044	WP_156667681.1	phenylalanine--tRNA ligase subunit alpha	-
GE022_RS06040 (GE022_006030)	endA	1241046..1241912 (-)	867	WP_003047901.1	DNA/RNA non-specific endonuclease	Machinery gene
GE022_RS06045 (GE022_006035)	-	1241948..1242136 (-)	189	WP_164405816.1	DNA-directed RNA polymerase subunit beta	-
GE022_RS06050 (GE022_006040)	murA	1242140..1243414 (-)	1275	WP_164405817.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
GE022_RS06055 (GE022_006045)	-	1243479..1243715 (-)	237	WP_282917434.1	DUF1146 family protein	-
GE022_RS06060 (GE022_006050)	-	1244015..1244431 (-)	417	WP_003047887.1	F0F1 ATP synthase subunit epsilon	-
GE022_RS06065 (GE022_006055)	atpD	1244444..1245850 (-)	1407	WP_093998505.1	F0F1 ATP synthase subunit beta	-
GE022_RS06070 (GE022_006060)	-	1246011..1246886 (-)	876	WP_003047882.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

Download Length: 288 a.a. Molecular weight: 31675.74 Da Isoelectric Point: 10.0123

                                >NTDB_id=447215 GE022_RS06040 WP_003047901.1 1241046..1241912(-) (endA) [Streptococcus canis strain HL_77_2]

MLTKKKRTRALNSLLLILLVLGSSYLAKSDLIASNHPIKQFYQTLVGEKKESSLTNNNLQADVPTEALAASVLTHSIKEQ

LGADIQWNGAGAFIINQNKTDLNAAVASLPYANNETKWVQGQKVPTRANALLDKSTRQYRDRSQLDKGYRSFKPAGWHQL

YPLKGSYDHAVDRGHLLGYALIGGLKGFDASTSNPNNIATQLSWANQADKSYATGQNYYEGLVRRALDKGHRVRYRVTLL

YDGDNLLASGSHLEAKSADGSLTFNVFVPNVQPGLTVDYRTGQIAINP

Nucleotide

Download Length: 867 bp

                                >NTDB_id=447215 GE022_RS06040 WP_003047901.1 1241046..1241912(-) (endA) [Streptococcus canis strain HL_77_2]

ATGTTAACAAAGAAAAAACGAACAAGAGCCCTTAATTCCTTGCTATTGATTTTATTAGTTTTGGGATCGAGTTACCTTGC

TAAAAGCGATTTAATTGCCAGTAATCACCCTATCAAGCAATTTTATCAAACCCTTGTTGGGGAGAAGAAGGAGTCATCAC

TCACAAATAATAACTTGCAGGCTGATGTTCCCACAGAAGCTCTGGCAGCATCTGTATTAACTCATTCAATCAAAGAGCAG

CTAGGTGCTGATATTCAGTGGAATGGGGCTGGAGCCTTTATTATTAACCAGAATAAAACAGATTTGAATGCAGCGGTGGC

CAGTCTGCCTTATGCCAACAATGAAACCAAATGGGTGCAAGGGCAAAAGGTTCCCACCAGAGCCAATGCCTTACTTGATA

AGTCAACACGGCAATATCGAGACCGCTCGCAACTTGATAAAGGTTACCGTTCATTTAAGCCAGCAGGTTGGCACCAATTG

TATCCTTTAAAAGGAAGTTATGACCATGCGGTGGATAGAGGGCATTTGCTAGGTTATGCTTTAATTGGCGGGCTGAAAGG

TTTTGATGCATCCACTAGCAATCCCAACAATATTGCTACTCAACTAAGCTGGGCCAATCAGGCGGATAAATCTTATGCAA

CAGGGCAAAATTACTATGAAGGGTTAGTACGTCGTGCTTTAGATAAGGGACATCGCGTCCGCTACCGTGTTACCCTGCTT

TATGATGGTGATAATTTACTAGCAAGCGGTAGCCATTTGGAGGCCAAATCAGCTGATGGCAGCTTGACTTTTAACGTGTT

TGTTCCAAATGTCCAACCAGGATTGACCGTTGACTATCGGACGGGACAGATAGCCATTAATCCCTGA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(95-246)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
endA	Streptococcus pneumoniae Rx1	56.818	91.667	0.521
endA	Streptococcus pneumoniae D39	56.818	91.667	0.521
endA	Streptococcus pneumoniae R6	56.818	91.667	0.521
endA	Streptococcus pneumoniae TIGR4	56.818	91.667	0.521

Detailed information NTG0447215