NTDB

Overview

Name	endA	Type	Machinery gene
Locus tag	GE023_RS06305	Genome accession	NZ_CP053789
Coordinates	1265665..1266531 (-)	Length	288 a.a.
NCBI ID	WP_003047901.1	Uniprot ID	A0AAV3FR50
Organism	Streptococcus canis strain HL_98_2
Function	cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1260665..1271531

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE023_RS06285 (GE023_006280)	-	1260735..1260919 (-)	185	Protein_1193	IS3 family transposase	-
GE023_RS10960	-	1260890..1261182 (+)	293	Protein_1194	integrase core domain-containing protein	-
GE023_RS06295 (GE023_006290)	pheT	1261217..1263622 (-)	2406	WP_164401517.1	phenylalanine--tRNA ligase subunit beta	-
GE023_RS06300 (GE023_006295)	pheS	1264339..1265382 (-)	1044	WP_156667681.1	phenylalanine--tRNA ligase subunit alpha	-
GE023_RS06305 (GE023_006300)	endA	1265665..1266531 (-)	867	WP_003047901.1	DNA/RNA non-specific endonuclease	Machinery gene
GE023_RS06310 (GE023_006305)	-	1266567..1266755 (-)	189	WP_003047898.1	DNA-directed RNA polymerase subunit beta	-
GE023_RS06315 (GE023_006310)	murA	1266759..1268033 (-)	1275	WP_159305097.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
GE023_RS06320 (GE023_006315)	-	1268098..1268334 (-)	237	WP_282917434.1	DUF1146 family protein	-
GE023_RS06325 (GE023_006320)	-	1268634..1269050 (-)	417	WP_159305870.1	F0F1 ATP synthase subunit epsilon	-
GE023_RS06330 (GE023_006325)	atpD	1269063..1270469 (-)	1407	WP_093998505.1	F0F1 ATP synthase subunit beta	-
GE023_RS06335 (GE023_006330)	-	1270630..1271505 (-)	876	WP_159305098.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

Download Length: 288 a.a. Molecular weight: 31675.74 Da Isoelectric Point: 10.0123

                                >NTDB_id=447161 GE023_RS06305 WP_003047901.1 1265665..1266531(-) (endA) [Streptococcus canis strain HL_98_2]

MLTKKKRTRALNSLLLILLVLGSSYLAKSDLIASNHPIKQFYQTLVGEKKESSLTNNNLQADVPTEALAASVLTHSIKEQ

LGADIQWNGAGAFIINQNKTDLNAAVASLPYANNETKWVQGQKVPTRANALLDKSTRQYRDRSQLDKGYRSFKPAGWHQL

YPLKGSYDHAVDRGHLLGYALIGGLKGFDASTSNPNNIATQLSWANQADKSYATGQNYYEGLVRRALDKGHRVRYRVTLL

YDGDNLLASGSHLEAKSADGSLTFNVFVPNVQPGLTVDYRTGQIAINP

Nucleotide

Download Length: 867 bp

                                >NTDB_id=447161 GE023_RS06305 WP_003047901.1 1265665..1266531(-) (endA) [Streptococcus canis strain HL_98_2]

ATGTTAACAAAGAAAAAACGAACAAGAGCCCTTAATTCCTTGCTATTGATTTTATTAGTTTTGGGATCGAGTTACCTTGC

TAAAAGCGATTTAATTGCCAGTAATCACCCTATCAAGCAATTTTATCAAACCCTTGTTGGGGAGAAGAAGGAGTCATCAC

TCACAAATAATAACTTGCAGGCTGATGTTCCCACAGAAGCTCTAGCAGCATCTGTATTAACTCATTCAATCAAAGAGCAG

CTAGGTGCTGATATTCAGTGGAATGGGGCTGGAGCCTTTATTATTAACCAGAATAAAACAGATTTGAATGCAGCGGTGGC

CAGTCTGCCTTATGCCAACAATGAAACCAAATGGGTGCAAGGGCAAAAGGTTCCCACCAGAGCCAATGCCTTACTTGATA

AGTCAACACGGCAATATCGAGACCGCTCGCAACTTGATAAAGGTTACCGTTCATTTAAGCCAGCAGGTTGGCACCAATTG

TATCCTTTAAAAGGAAGTTATGACCATGCGGTGGATAGAGGGCATTTGCTAGGTTATGCTTTAATTGGCGGGCTAAAAGG

TTTTGATGCATCCACTAGCAATCCCAACAATATTGCTACTCAACTAAGCTGGGCCAATCAGGCGGATAAATCTTATGCAA

CAGGGCAAAATTACTATGAAGGCTTAGTACGTCGTGCTTTAGATAAGGGACATCGCGTCCGCTACCGTGTCACCCTGCTT

TATGATGGTGATAATTTACTAGCAAGCGGTAGCCATTTGGAGGCCAAATCAGCTGATGGCAGCTTGACTTTTAACGTGTT

TGTTCCAAATGTCCAACCAGGATTGACCGTTGACTATCGGACGGGACAGATAGCCATTAATCCCTGA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(95-246)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
endA	Streptococcus pneumoniae Rx1	56.818	91.667	0.521
endA	Streptococcus pneumoniae D39	56.818	91.667	0.521
endA	Streptococcus pneumoniae R6	56.818	91.667	0.521
endA	Streptococcus pneumoniae TIGR4	56.818	91.667	0.521

Detailed information NTG0447161