Detailed information NTG0445914

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: I3K80_RS05080
• Genome accession: NZ_CP065194
• Coordinates: 1012523..1015141 (+)
• Length: 872 a.a.
• NCBI ID: WP_196848172.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain GDC6P096P
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1007523..1020141

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I3K80_RS05055 (I3K80_05055)	-	1008379..1009326 (+)	948	WP_000121214.1	IS30-like element ISSau1 family transposase	-
I3K80_RS05060 (I3K80_05060)	-	1009365..1009658 (+)	294	WP_000655666.1	thiamine-binding protein	-
I3K80_RS05065 (I3K80_05065)	miaB	1009792..1011336 (+)	1545	WP_001001522.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
I3K80_RS05070 (I3K80_05070)	-	1011337..1011702 (+)	366	WP_000282384.1	RicAFT regulatory complex protein RicA family protein	-
I3K80_RS05075 (I3K80_05075)	thiW	1011729..1012220 (+)	492	WP_000842283.1	energy coupling factor transporter S component ThiW	-
I3K80_RS05080 (I3K80_05080)	hexA	1012523..1015141 (+)	2619	WP_196848172.1	DNA mismatch repair protein MutS	Machinery gene
I3K80_RS05085 (I3K80_05085)	hexB	1015154..1017163 (+)	2010	WP_000516257.1	DNA mismatch repair endonuclease MutL	Machinery gene
I3K80_RS05090 (I3K80_05090)	-	1017169..1017711 (+)	543	WP_001072706.1	glycerol-3-phosphate responsive antiterminator	-
I3K80_RS05095 (I3K80_05095)	-	1018186..1019004 (+)	819	WP_001103747.1	MIP/aquaporin family protein	-

Sequence

Protein

• Length: 872 a.a.
• Molecular weight: 99917.62 Da
• Isoelectric Point: 4.6322

>NTDB_id=445914 I3K80_RS05080 WP_196848172.1 1012523..1015141(+) (hexA) [Staphylococcus aureus strain GDC6P096P]
MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNN
GYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATL
LNEITTINPNEVVINDNISDHLKRQINMVTETITVRETLSTEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVV
QYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIER
DTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQDTLVQVNQLEPLDDLLDILEQSLVEEPP
ISVKDGGLFKVGFNMQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQ
TLSNAERFITDELKEKEDIILGAEDKAIELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFS
ENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQ
IFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHEL
TTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLKMV
ENEPEINQENSNLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMTPIEALAKLSELQNQLK

Nucleotide

• Length: 2619 bp

>NTDB_id=445914 I3K80_RS05080 WP_196848172.1 1012523..1015141(+) (hexA) [Staphylococcus aureus strain GDC6P096P]
ATGTCTAATGTTACACCAATGATGCAGCAATATTTAAAAATAAAATCAGAATACCAAGATTGCTTATTATTTTTTAGACT
AGGTGATTTCTATGAAATGTTTTATGAAGATGCCAAGGAGGCATCACGTGTACTTGAAATTACTTTAACTAAAAGAGATG
CTAAAAAAGAAAATCCAATTCCGATGTGTGGTGTTCCGTATCATTCTGCAGATAGTTATATAGATACACTTGTTAATAAT
GGATATAAAGTAGCTATTTGTGAACAGATGGAAGATCCGAAACAAACGAAAGGTATGGTTAGACGTGAGGTAGTAAGAAT
TGTGACTCCAGGAACTGTGATGGAGCAAGGTGGTGTAGATGATAAACAAAATAACTATATTTTAAGTTTTGTTATGAATC
AACCTGAAATTGCGCTTAGTTACTGTGATGTTTCTACTGGTGAATTAAAGGTTACACATTTTAATGATGAAGCGACTTTA
TTAAATGAAATTACGACGATAAACCCTAACGAAGTTGTTATCAATGACAATATTTCCGATCATTTAAAAAGACAAATTAA
TATGGTGACAGAAACAATAACAGTCAGGGAAACGTTATCAACAGAAATCTATAGTGTGAATCAAACTGAACATAAATTAA
TGTATCAAGCGACACAATTATTGCTAGATTATATTCATCATACACAAAAACGTGATTTATCGCATATCGAGGATGTTGTT
CAATATGCAGCTATAGATTATATGAAAATGGATTTTTATGCTAAGAGAAACCTTGAGTTAACGGAAAGCATTCGATTAAA
ATCAAAAAAAGGAACGCTACTTTGGCTAATGGACGAAACGAAAACACCAATGGGAGCACGCCGCTTAAAACAATGGATAG
ATAGACCACTAATAAGTAAAGAACAAATTGAAGCACGATTAGATATCGTTGATGAATTTAGTGCTCATTTCATAGAAAGA
GACACCTTAAGAACATATCTTAATCAAGTGTATGATATTGAACGTCTTGTTGGGCGTGTTAGTTACGGAAATGTTAATGC
GAGAGATTTAATTCAACTTAAACATTCCATTTCTGAGATACCAAATATTAAAGCATTACTAAATTCTATGAATCAGGATA
CTCTTGTACAAGTTAATCAACTGGAGCCACTTGATGATTTACTTGATATATTAGAACAGAGTTTAGTAGAAGAACCACCA
ATTTCAGTTAAAGATGGTGGACTATTCAAAGTTGGTTTTAATATGCAATTAGATGAATATCTTGAAGCTTCAAAAAACGG
AAAAACATGGTTAGCAGAATTACAAGCCAAAGAAAGACAACGTACTGGAATAAAATCATTGAAAATAAGCTTTAATAAAG
TGTTTGGTTATTTTATAGAAATAACACGTGCCAACTTGCAAAATTTTGAACCAAGTGAATTTGGTTATATGAGGAAGCAA
ACGTTATCGAATGCGGAACGATTTATAACTGATGAACTTAAAGAAAAAGAAGATATCATTTTAGGTGCGGAAGACAAAGC
CATTGAATTAGAATATCAATTATTTGTTCAGCTACGTGAAGAAGTTAAAAAATATACTGAACGTTTACAACAACAAGCTA
AAATTATTTCAGAGTTAGATTGTTTACAGAGCTTTGCAGAAATTGCTCAAAAATATAATTATACTAGGCCTTCATTTAGT
GAAAATAAAACATTAGAATTAGTGGAATCTAGGCACCCTGTAGTGGAAAGAGTAATGGATTATAATGACTATGTGCCTAA
TAATTGTCGATTAGATAACGAAACATTTATATATTTAATTACAGGTCCGAATATGTCTGGTAAATCGACGTATATGAGAC
AAGTTGCCATAATTAGTATAATGGCCCAAATGGGAGCTTATGTCCCTTGTAAAGAGGCTGTGTTACCTATATTTGATCAA
ATATTCACTAGAATAGGTGCGGCAGATGATTTGGTTTCAGGTAAGAGTACGTTTATGGTAGAAATGCTAGAAGCACAAAA
GGCATTAACTTATGCAACAGAGGATAGTTTGATTATTTTCGATGAAATTGGACGTGGTACTTCAACGTATGACGGTTTAG
CTTTAGCGCAGGCAATGATAGAGTATGTAGCTGAAACATCACATGCTAAAACGTTATTTTCAACACATTATCATGAATTG
ACAACATTAGATCAAGCATTACCAAGTCTAAAAAATGTTCACGTCGCTGCTAATGAATATAAAGGTGAACTTATATTCTT
GCATAAAGTCAAAGATGGTGCAGTTGACGATAGTTATGGTATTCAAGTTGCGAAATTAGCTGATTTACCTGAAAAAGTTA
TTAGCAGAGCACAAGTGATCCTAAGCGAGTTTGAAGCGTCTGCTGGTAAAAAATCATCGATATCAAATTTAAAAATGGTC
GAAAATGAACCTGAAATTAATCAAGAAAATTCAAACTTAAGTGTTGAAGAAACAACTGATACTTTATCTCAAAAAGACTT
TGAACAAGCATCATTTGATTTGTTTGAAAATGATCAAGAAAGCGAGATTGAACTACAAATTAAAAATTTGAATTTATCTA
ATATGACACCAATTGAGGCATTGGCGAAGTTAAGTGAATTACAAAATCAATTAAAATAG

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (5-115)

• MutS family domain IV (MutS_IV) (412-505)

• MutS domain II (MutS_II) (125-237)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	45.455	100	0.459