Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IPT86_RS09475 Genome accession   NZ_CP064847
Coordinates   1955857..1956513 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 20     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1950857..1961513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IPT86_RS09445 (IPT86_09445) dcyD 1951737..1952723 (+) 987 WP_001128235.1 D-cysteine desulfhydrase -
  IPT86_RS09450 (IPT86_09450) tcyL 1952738..1953406 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IPT86_RS09455 (IPT86_09455) tcyN 1953403..1954155 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IPT86_RS09460 (IPT86_09460) sdiA 1954385..1955107 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  IPT86_RS09465 (IPT86_09465) yecF 1955174..1955398 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IPT86_RS09470 (IPT86_09470) yecU 1955385..1955561 (-) 177 WP_032160694.1 protein YecU -
  IPT86_RS09475 (IPT86_09475) letA 1955857..1956513 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IPT86_RS09480 (IPT86_09480) uvrC 1956510..1958342 (+) 1833 WP_075862275.1 excinuclease ABC subunit UvrC Machinery gene
  IPT86_RS09485 (IPT86_09485) pgsA 1958399..1958947 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IPT86_RS09505 (IPT86_09505) yecA 1959596..1960261 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=445281 IPT86_RS09475 WP_000611328.1 1955857..1956513(+) (letA) [Escherichia coli strain 20]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=445281 IPT86_RS09475 WP_000611328.1 1955857..1956513(+) (letA) [Escherichia coli strain 20]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482