Detailed information NTG0443139

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: IUJ41_RS12470
• Genome accession: NZ_CP064365
• Coordinates: 2501510..2504128 (-)
• Length: 872 a.a.
• NCBI ID: WP_000073353.1
• Uniprot ID: P0C1S1
• Organism: Staphylococcus aureus strain PartF-Saureus-RM8376
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2496510..2509128

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ41_RS12455 (IUJ41_12425)	-	2497657..2498475 (-)	819	WP_001103743.1	MIP/aquaporin family protein	-
IUJ41_RS12460 (IUJ41_12430)	-	2498940..2499482 (-)	543	WP_001077635.1	glycerol-3-phosphate responsive antiterminator	-
IUJ41_RS12465 (IUJ41_12435)	hexB	2499488..2501497 (-)	2010	WP_000516261.1	DNA mismatch repair endonuclease MutL	Machinery gene
IUJ41_RS12470 (IUJ41_12440)	hexA	2501510..2504128 (-)	2619	WP_000073353.1	DNA mismatch repair protein MutS	Machinery gene
IUJ41_RS12475 (IUJ41_12445)	thiW	2504431..2504922 (-)	492	WP_000842277.1	energy coupling factor transporter S component ThiW	-
IUJ41_RS12480 (IUJ41_12450)	-	2504949..2505314 (-)	366	WP_000282388.1	RicAFT regulatory complex protein RicA family protein	-
IUJ41_RS12485 (IUJ41_12455)	miaB	2505315..2506859 (-)	1545	WP_001001523.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
IUJ41_RS12490 (IUJ41_12460)	-	2506993..2507286 (-)	294	WP_000655666.1	MTH1187 family thiamine-binding protein	-
IUJ41_RS12495 (IUJ41_12465)	-	2507380..2508246 (-)	867	WP_000190144.1	2-oxoacid:ferredoxin oxidoreductase subunit beta	-

Sequence

Protein

• Length: 872 a.a.
• Molecular weight: 99902.68 Da
• Isoelectric Point: 4.6660

>NTDB_id=443139 IUJ41_RS12470 WP_000073353.1 2501510..2504128(-) (hexA) [Staphylococcus aureus strain PartF-Saureus-RM8376]
MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNN
GYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATL
LNEITTINPNEVVINDNISDNLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVV
QYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIER
DTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQNTLVQVNQLEPLDDLLDILEQSLVEEPP
ISVKDGGLFKVGFNTQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQ
TLSNAERFITDELKEKEDIILGAEDKAIELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFS
ENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQ
IFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHEL
TTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLKMV
ENEPEINQENLNLSVEETTDTLSQKDFEQASFDLFENDQKSEIELQIKNLNLSNMTPIEALVKLSELQNQLK

Nucleotide

• Length: 2619 bp

>NTDB_id=443139 IUJ41_RS12470 WP_000073353.1 2501510..2504128(-) (hexA) [Staphylococcus aureus strain PartF-Saureus-RM8376]
ATGTCTAATGTTACACCAATGATGCAGCAATATTTAAAAATAAAATCAGAATACCAAGATTGCTTATTATTTTTTAGACT
AGGTGATTTCTATGAAATGTTTTATGAAGATGCCAAGGAGGCATCACGTGTACTTGAAATTACTTTAACTAAAAGAGATG
CTAAAAAAGAAAATCCAATTCCGATGTGTGGTGTTCCGTATCATTCTGCAGATAGTTATATAGATACACTTGTTAATAAT
GGATATAAAGTAGCTATTTGTGAACAGATGGAAGATCCGAAACAAACGAAAGGTATGGTTAGACGTGAGGTAGTAAGAAT
TGTGACTCCAGGAACTGTGATGGAGCAAGGTGGTGTAGATGATAAACAAAATAACTATATTTTAAGTTTTGTTATGAATC
AACCTGAAATTGCGCTTAGTTACTGTGATGTTTCTACTGGCGAATTAAAGGTTACACATTTTAATGATGAAGCGACTTTA
TTAAATGAAATTACGACGATAAACCCTAACGAAGTTGTTATCAATGACAATATTTCCGATAATTTAAAAAGACAAATTAA
TATGGTGACAGAAACAATAACAGTCAGGGAAACGTTATCATCAGAAATCTATAGTGTGAATCAAACTGAACATAAATTAA
TGTATCAAGCGACACAATTATTGCTAGATTATATTCATCATACACAAAAACGTGATTTATCGCATATCGAGGATGTTGTT
CAATATGCAGCTATAGATTATATGAAAATGGATTTTTATGCTAAGAGAAACCTTGAGTTAACGGAAAGCATTCGATTAAA
ATCAAAAAAAGGAACGCTACTTTGGCTAATGGACGAAACGAAAACACCAATGGGAGCACGCCGCTTAAAACAATGGATAG
ATAGACCACTAATAAGTAAAGAACAAATTGAAGCACGATTAGATATCGTTGATGAATTTAGTGCTCATTTCATAGAAAGA
GACACCTTAAGAACATATCTTAATCAAGTGTATGATATTGAACGTCTTGTTGGGCGTGTTAGTTACGGAAATGTTAATGC
GAGAGATTTAATTCAACTTAAACATTCCATTTCTGAAATACCGAATATTAAAGCATTACTAAATTCTATGAATCAGAATA
CTCTTGTACAAGTTAATCAACTAGAACCCCTTGATGATTTACTTGATATATTAGAACAGAGTTTAGTAGAAGAACCACCA
ATTTCAGTTAAAGATGGCGGACTATTCAAAGTTGGTTTTAATACGCAATTAGATGAATATCTTGAAGCTTCAAAAAACGG
AAAAACATGGTTAGCAGAATTACAAGCCAAAGAAAGACAACGTACAGGAATAAAATCATTGAAAATAAGCTTTAATAAAG
TGTTTGGTTATTTTATAGAAATAACACGTGCCAACTTGCAAAATTTTGAACCAAGTGAATTTGGTTATATGAGGAAGCAA
ACGTTATCGAATGCTGAACGTTTTATAACTGATGAACTTAAAGAAAAAGAAGATATCATTTTAGGTGCGGAAGACAAAGC
CATCGAATTAGAATATCAATTATTTGTTCAGCTACGTGAAGAAGTTAAAAAATATACTGAACGTTTACAACAACAAGCTA
AAATTATTTCAGAGCTAGATTGTTTACAGAGCTTTGCAGAAATTGCTCAAAAATATAATTACACTAGGCCTTCATTTAGT
GAAAATAAAACATTAGAATTAGTGGAATCTAGGCACCCAGTAGTGGAAAGAGTAATGGATTATAATGACTATGTGCCTAA
TAATTGTCGATTAGATAATGAAACATTTATATATTTAATTACAGGTCCGAATATGTCTGGTAAATCGACATATATGAGAC
AAGTTGCCATAATTAGTATAATGGCCCAAATGGGAGCTTATGTCCCTTGTAAAGAGGCAGTGTTACCTATATTTGATCAA
ATATTCACTAGAATAGGTGCGGCAGATGATTTGGTTTCAGGTAAGAGTACGTTTATGGTAGAAATGCTAGAAGCACAAAA
GGCATTAACTTATGCAACAGAGGATAGTTTGATTATTTTCGATGAAATTGGACGTGGTACTTCAACGTATGACGGTTTAG
CTTTAGCGCAGGCAATGATAGAGTATGTAGCTGAAACATCACATGCTAAAACGTTATTTTCAACACATTATCATGAATTG
ACAACATTAGATCAAGCATTACCAAGTCTAAAAAATGTTCACGTCGCTGCTAATGAATATAAAGGTGAACTTATATTCTT
GCATAAAGTCAAAGATGGTGCAGTTGACGATAGTTATGGTATTCAAGTTGCGAAATTAGCTGATTTACCTGAAAAAGTTA
TTAGCAGAGCACAAGTGATTCTAAGCGAGTTTGAAGCGTCTGCTGGTAAAAAATCATCGATATCAAATTTAAAAATGGTC
GAAAATGAACCTGAAATTAATCAAGAAAATTTAAACTTAAGTGTTGAAGAAACAACTGATACTTTATCTCAAAAAGACTT
TGAACAAGCATCATTTGATTTGTTTGAAAATGATCAAAAAAGCGAGATTGAACTACAAATTAAAAATTTGAATTTATCTA
ATATGACACCAATTGAGGCATTGGTGAAGTTAAGTGAATTACAAAATCAATTAAAATAG

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (412-505)

• MutS domain I (MutS_I) (5-115)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (125-237)

3D structure

• AlphaFold DB: P0C1S1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	45.341	100	0.458