Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   HHM66_RS05205 Genome accession   NZ_CP053074
Coordinates   1041484..1042794 (-) Length   436 a.a.
NCBI ID   WP_065957651.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1036484..1047794
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM66_RS05175 (HHM66_05180) - 1036918..1037307 (-) 390 WP_003058840.1 cytidine deaminase -
  HHM66_RS05180 (HHM66_05185) deoC 1037294..1037956 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  HHM66_RS05185 (HHM66_05190) - 1037972..1039249 (-) 1278 WP_015057596.1 pyrimidine-nucleoside phosphorylase -
  HHM66_RS05190 (HHM66_05195) - 1039236..1039835 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  HHM66_RS05195 (HHM66_05200) coaA 1040104..1041024 (+) 921 WP_012766986.1 type I pantothenate kinase -
  HHM66_RS05200 (HHM66_05205) rpsT 1041078..1041326 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  HHM66_RS05205 (HHM66_05210) ciaH 1041484..1042794 (-) 1311 WP_065957651.1 HAMP domain-containing sensor histidine kinase Regulator
  HHM66_RS05210 (HHM66_05215) ciaR 1042787..1043461 (-) 675 WP_003060678.1 response regulator transcription factor Regulator
  HHM66_RS05215 (HHM66_05220) - 1043665..1046202 (-) 2538 WP_014612305.1 M1 family metallopeptidase -
  HHM66_RS05220 (HHM66_05225) phoU 1046403..1047056 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49903.43 Da        Isoelectric Point: 8.2375

>NTDB_id=442782 HHM66_RS05205 WP_065957651.1 1041484..1042794(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
MNKLKKEVFSDQYNHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIVIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=442782 HHM66_RS05205 WP_065957651.1 1041484..1042794(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACAACCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTGTTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.142

100

0.514
  ciaH Streptococcus pneumoniae D39

51.142

100

0.514
  ciaH Streptococcus pneumoniae R6

51.142

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.142

100

0.514