Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   HHM66_RS03735 Genome accession   NZ_CP053074
Coordinates   727021..727887 (+) Length   288 a.a.
NCBI ID   WP_015057471.1    Uniprot ID   A0AB33R5M0
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 722021..732887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM66_RS03710 (HHM66_03715) atpD 723057..724463 (+) 1407 WP_003057452.1 F0F1 ATP synthase subunit beta -
  HHM66_RS03715 (HHM66_03720) - 724476..724892 (+) 417 WP_003050138.1 F0F1 ATP synthase subunit epsilon -
  HHM66_RS03720 (HHM66_03725) - 725221..725457 (+) 237 WP_274047614.1 DUF1146 family protein -
  HHM66_RS03725 (HHM66_03730) murA 725522..726793 (+) 1272 WP_015057470.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  HHM66_RS03730 (HHM66_03735) - 726797..726985 (+) 189 WP_003057490.1 DNA-directed RNA polymerase subunit beta -
  HHM66_RS03735 (HHM66_03740) endA 727021..727887 (+) 867 WP_015057471.1 DNA/RNA non-specific endonuclease Machinery gene
  HHM66_RS03740 (HHM66_03745) pheS 728170..729213 (+) 1044 WP_003061661.1 phenylalanine--tRNA ligase subunit alpha -
  HHM66_RS03745 (HHM66_03750) pheT 729423..731828 (+) 2406 WP_015057472.1 phenylalanine--tRNA ligase subunit beta -
  HHM66_RS03750 (HHM66_03755) - 731938..732315 (+) 378 WP_015057473.1 OsmC family protein -
  HHM66_RS03755 (HHM66_03760) - 732308..732694 (+) 387 WP_015057474.1 DUF1722 domain-containing protein -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 31887.91 Da        Isoelectric Point: 10.0750

>NTDB_id=442778 HHM66_RS03735 WP_015057471.1 727021..727887(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
MLARKKRKRVLNSFLLILLVLGSSYLAKSDFIASNHPIKQIYRTVLGDKGESSSESKEVYSEVPTEALSASVLTKSIKEQ
LGSDIEWNGAGAYIINRNKTDLNASVASLPYANNETKWVQGQKVPTRANALLTKSTRQYRNRYQTDNAYRTFKPAGWHQL
HHLKGNYDHAVDRGHLLGYALVGGLKGFDASTSNPDNIATQLSWANQADKPYSTGQNYYEGLVRRALDKGKRVRYRVTLL
YDGDNLLASGSQLEAKSADGSLAFNVFVPNVQAGLTVDYRTGQIAINP

Nucleotide


Download         Length: 867 bp        

>NTDB_id=442778 HHM66_RS03735 WP_015057471.1 727021..727887(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
ATGTTAGCAAGGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAGTTACCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATTAAGCAAATTTATCGTACCGTTTTGGGAGATAAGGGTGAATCATCAT
CAGAATCAAAAGAAGTCTATAGTGAGGTTCCCACAGAAGCCCTATCCGCTTCTGTCTTGACCAAATCCATTAAGGAACAA
TTAGGTTCCGATATTGAATGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAACGCAAGCGTAGC
CAGTCTGCCCTATGCCAATAATGAAACCAAATGGGTCCAAGGACAAAAGGTTCCTACTAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTACCTTCAAGCCTGCTGGTTGGCACCAATTA
CATCACTTAAAAGGAAATTATGACCACGCAGTTGATAGAGGACATTTGCTAGGTTATGCTTTAGTCGGTGGACTGAAAGG
TTTTGATGCATCTACCAGTAATCCTGATAACATTGCTACTCAACTAAGTTGGGCCAATCAAGCAGATAAACCCTATTCGA
CAGGTCAAAATTACTATGAAGGCTTAGTACGTCGTGCATTGGATAAGGGCAAAAGGGTACGTTATCGTGTTACCTTGCTT
TATGATGGTGATAACCTGTTAGCCAGTGGTAGCCAGTTAGAGGCCAAATCTGCCGATGGGAGTTTAGCATTTAACGTGTT
TGTTCCAAATGTTCAAGCAGGGCTGACGGTTGATTATCGAACAGGACAGATTGCCATCAATCCCTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(121-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

62.338

80.208

0.5
  endA Streptococcus pneumoniae D39

62.338

80.208

0.5
  endA Streptococcus pneumoniae R6

62.338

80.208

0.5
  endA Streptococcus pneumoniae TIGR4

62.338

80.208

0.5