Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   HMPREF1038_RS07910 Genome accession   NC_018630
Coordinates   1482615..1483292 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae gamPNI0373     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1477615..1488292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS07885 (HMPREF1038_01613) - 1477776..1478405 (-) 630 WP_001844547.1 NAD(P)-dependent oxidoreductase -
  HMPREF1038_RS07890 - 1478644..1478844 (+) 201 WP_001845636.1 hypothetical protein -
  HMPREF1038_RS07895 (HMPREF1038_01614) - 1479275..1479598 (+) 324 WP_025172496.1 hypothetical protein -
  HMPREF1038_RS07900 (HMPREF1038_01615) thrS 1479656..1481599 (+) 1944 WP_025172495.1 threonine--tRNA ligase -
  HMPREF1038_RS07905 (HMPREF1038_01616) - 1481648..1482622 (-) 975 WP_000887964.1 HAMP domain-containing histidine kinase -
  HMPREF1038_RS07910 (HMPREF1038_01617) braR 1482615..1483292 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  HMPREF1038_RS07915 (HMPREF1038_01618) - 1483448..1484521 (+) 1074 WP_001273823.1 DUF2974 domain-containing protein -
  HMPREF1038_RS07920 (HMPREF1038_01619) - 1484612..1484914 (-) 303 WP_000281608.1 hypothetical protein -
  HMPREF1038_RS07925 (HMPREF1038_01620) - 1484982..1485419 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  HMPREF1038_RS07930 (HMPREF1038_01621) - 1485495..1486337 (-) 843 WP_000160934.1 metallophosphoesterase -
  HMPREF1038_RS07935 (HMPREF1038_01622) - 1486449..1487099 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  HMPREF1038_RS07945 (HMPREF1038_01624) - 1487276..1487923 (+) 648 WP_001844541.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=44224 HMPREF1038_RS07910 WP_000548959.1 1482615..1483292(-) (braR) [Streptococcus pneumoniae gamPNI0373]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=44224 HMPREF1038_RS07910 WP_000548959.1 1482615..1483292(-) (braR) [Streptococcus pneumoniae gamPNI0373]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment