Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HG567_RS00100 Genome accession   NZ_CP051500
Coordinates   13996..16359 (+) Length   787 a.a.
NCBI ID   WP_202139729.1    Uniprot ID   -
Organism   Helicobacter pylori strain PUNO-003     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 8996..21359
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG567_RS00070 (HG567_00070) groES 9016..9372 (-) 357 WP_000671934.1 co-chaperone GroES -
  HG567_RS00075 (HG567_00075) dnaG 9659..11338 (+) 1680 WP_202139725.1 DNA primase -
  HG567_RS00080 (HG567_00080) - 11335..12387 (+) 1053 WP_202139726.1 MnmA/TRMU family protein -
  HG567_RS00085 (HG567_00085) - 12477..13304 (+) 828 WP_202139727.1 DUF5718 family protein -
  HG567_RS00090 (HG567_00090) comB2 13450..13731 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HG567_RS00095 (HG567_00095) comB3 13731..13994 (+) 264 WP_202139728.1 competence protein ComB Machinery gene
  HG567_RS00100 (HG567_00100) comB4 13996..16359 (+) 2364 WP_202139729.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HG567_RS00110 (HG567_00110) - 16668..18008 (+) 1341 WP_202139730.1 COG3014 family protein -
  HG567_RS00115 (HG567_00115) cheV1 18118..19083 (+) 966 WP_120916061.1 chemotaxis protein CheV1 -
  HG567_RS00120 (HG567_00120) nspC 19080..20297 (+) 1218 WP_202139731.1 carboxynorspermidine decarboxylase -
  HG567_RS00125 (HG567_00125) lpxE 20319..20828 (-) 510 WP_237393065.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90193.59 Da        Isoelectric Point: 7.9321

>NTDB_id=439172 HG567_RS00100 WP_202139729.1 13996..16359(+) (comB4) [Helicobacter pylori strain PUNO-003]
MLEKLLSAVKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQSDSKYLQAILNQFENKEVYENQYFLVLESTHSLHGVLEHKKKSFMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSAHKTLSFLKERAKFSMSSLVKNELLEYQELVKTKRLSMQKFA
LNVLIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISCAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=439172 HG567_RS00100 WP_202139729.1 13996..16359(+) (comB4) [Helicobacter pylori strain PUNO-003]
ATGTTAGAAAAGCTTTTGAGCGCTGTCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTCTTGCTCACTAAAAACGAAAACTTAGTGGGAATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAATCTGATTCTAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAACAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTTTGCATGGTGTTTTGGAGCATAAGAAAAAATCTTTCATGCATGCTAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAATGGGTTTGATCTCCCCCTAAAACCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCCATCACTTTTGAAAAAGATTACTTCATTCAAGAGAGCTTTAACCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
TTTGGATATTATCTTTTCCATAGAGCCTATGAGCGCGCATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCTAGTCTTGTTAAAAACGAGCTATTAGAATACCAAGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAATAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTCGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTTGTGCGATTAAGAGCCTTTATGAGACCCTATACCCCAAAGATTTTAGTTTGCTAGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAACGTGATAAACCTAGATGCGATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAGATCTTAGAAGAGTCCAGGAAAAACGACAGCGGGTTTTTGGTTTTTTTAGAC
GAATTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCCTTGCAAGACATTTACCAATTAAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACAATTTTAATGTGCCTTTGAGCGAGACTGAAATTTCA
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGTTCTAACATGATTGACGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCGGATTCTAGTCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.713

100

0.977