Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HG573_RS00100 Genome accession   NZ_CP051494
Coordinates   14295..16658 (+) Length   787 a.a.
NCBI ID   WP_202147345.1    Uniprot ID   -
Organism   Helicobacter pylori strain PUNO-010     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9295..21658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG573_RS00070 (HG573_00070) groES 9311..9667 (-) 357 WP_000671930.1 co-chaperone GroES -
  HG573_RS00075 (HG573_00075) dnaG 9956..11635 (+) 1680 WP_202147343.1 DNA primase -
  HG573_RS00080 (HG573_00080) - 11632..12684 (+) 1053 WP_121045909.1 MnmA/TRMU family protein -
  HG573_RS00085 (HG573_00085) - 12776..13603 (+) 828 WP_202147344.1 DUF5718 family protein -
  HG573_RS00090 (HG573_00090) comB2 13749..14030 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HG573_RS00095 (HG573_00095) comB3 14030..14293 (+) 264 WP_000584956.1 hypothetical protein Machinery gene
  HG573_RS00100 (HG573_00100) comB4 14295..16658 (+) 2364 WP_202147345.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HG573_RS00110 (HG573_00110) - 16963..18303 (+) 1341 WP_202147808.1 COG3014 family protein -
  HG573_RS00115 (HG573_00115) cheV1 18409..19374 (+) 966 WP_024948933.1 chemotaxis protein CheV1 -
  HG573_RS00120 (HG573_00120) nspC 19371..20588 (+) 1218 WP_202147346.1 carboxynorspermidine decarboxylase -
  HG573_RS00125 (HG573_00125) lpxE 20598..21131 (-) 534 WP_237392935.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90040.43 Da        Isoelectric Point: 8.2616

>NTDB_id=439042 HG573_RS00100 WP_202147345.1 14295..16658(+) (comB4) [Helicobacter pylori strain PUNO-010]
MLEKLLGAIKQKVSNYFLGALPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDRQQNIQSDSKYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQEGFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNVLIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISYLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISGAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSSAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=439042 HG573_RS00100 WP_202147345.1 14295..16658(+) (comB4) [Helicobacter pylori strain PUNO-010]
ATGTTAGAAAAGCTTTTAGGCGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGCTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTCTTGCTCACTAAAAACGAAAACTTAGTGGGAATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAGATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATCGCCAACAAAACATTCAATCTGATTCTAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCGCGC
ACTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCCTTAATGCATGCCAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCGGAATACATTAATGGGTTTGATCTCCCTTTAAAGCCTCTAGTAGGAGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTACTTCATTCAAGAGGGTTTTAACCAAAAAACCTATAAC
CGCTTGATTGGCATTAAGGCTTATGAGAGCGAACGTATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
TTTGGATATTATCTTTTCCATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGGGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAGGAATTAGTCAAAACCAAACGCTTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTGGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAATCGCTAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTATTTAATGATGAGCGCTTTAAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCAAGGGCTT
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATCTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTTGATCTCGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTGGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGATTTTAGTTTGCTGGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAATTCCAGTGCTTTTTTAAACGTGATAAACCTAGACGCGATCACCCAAAACCCTAAAGATTTGG
GGCTTTTAGCCTATTACTTGTTTTATAAGATCTTAGAAGAGTCCAGGAAAAACGACAGTGGCTTTTTGGTTTTTTTAGAC
GAATTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCCTTGCAAGATATTTACCAACTTAGCGGGGTTAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTCATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACAATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCA
TTTTTAGAAAACACCCCTCTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGCTCTAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAGATCTTTAATTCAGATTCTAGCCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.078

100

0.971