Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   HGK49_RS00085 Genome accession   NZ_CP051434
Coordinates   11260..11541 (+) Length   93 a.a.
NCBI ID   WP_001272686.1    Uniprot ID   G2MDJ3
Organism   Helicobacter pylori strain ASHA-004     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 6260..16541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HGK49_RS00065 (HGK49_00065) groES 6836..7192 (-) 357 WP_202132903.1 co-chaperone GroES -
  HGK49_RS00070 (HGK49_00070) dnaG 7467..9146 (+) 1680 WP_202132904.1 DNA primase -
  HGK49_RS00075 (HGK49_00075) - 9143..10195 (+) 1053 WP_000802572.1 MnmA/TRMU family protein -
  HGK49_RS00080 (HGK49_00080) - 10287..11114 (+) 828 WP_202132905.1 DUF5718 family protein -
  HGK49_RS00085 (HGK49_00085) comB2 11260..11541 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HGK49_RS00090 (HGK49_00090) comB3 11541..11804 (+) 264 WP_000584955.1 hypothetical protein Machinery gene
  HGK49_RS00095 (HGK49_00095) comB4 11806..14169 (+) 2364 WP_202132906.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HGK49_RS00105 (HGK49_00105) - 14399..15829 (+) 1431 WP_202132907.1 COG3014 family protein -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10539.81 Da        Isoelectric Point: 9.1450

>NTDB_id=438259 HGK49_RS00085 WP_001272686.1 11260..11541(+) (comB2) [Helicobacter pylori strain ASHA-004]
MSAHFLKIIFLVGMCVSSLFAEGLEGFFNALEAQLKSPIAKGILMVIFIGIAIYVWRNLDRWKEILFTILGVVFGIFLFF
KAPSLANWFMGIF

Nucleotide


Download         Length: 282 bp        

>NTDB_id=438259 HGK49_RS00085 WP_001272686.1 11260..11541(+) (comB2) [Helicobacter pylori strain ASHA-004]
ATGTCCGCTCATTTTTTAAAAATCATTTTTTTAGTAGGCATGTGCGTTTCAAGCTTGTTCGCTGAAGGTTTAGAGGGGTT
TTTTAACGCCCTAGAAGCCCAGCTCAAAAGCCCCATCGCTAAGGGGATTTTAATGGTGATTTTCATAGGGATCGCTATTT
ATGTGTGGAGGAATTTGGACCGGTGGAAAGAGATTTTATTCACGATCCTTGGCGTGGTGTTTGGGATTTTTTTATTCTTT
AAAGCCCCGAGTTTAGCGAATTGGTTCATGGGAATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(6-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G2MDJ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

98.925

100

0.989