Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   SMUGS5_RS08455 Genome accession   NC_018089
Coordinates   1747524..1749854 (-) Length   776 a.a.
NCBI ID   WP_002274341.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1742524..1754854
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS08435 (SMUGS5_08380) - 1742861..1743106 (-) 246 WP_002263367.1 hypothetical protein -
  SMUGS5_RS10495 (SMUGS5_08385) - 1743410..1743580 (+) 171 WP_014835034.1 hypothetical protein -
  SMUGS5_RS08440 (SMUGS5_08390) mutY 1744651..1745796 (+) 1146 WP_014835035.1 A/G-specific adenine glycosylase -
  SMUGS5_RS08445 (SMUGS5_08395) - 1745988..1747037 (-) 1050 WP_014835036.1 zinc-dependent alcohol dehydrogenase family protein -
  SMUGS5_RS08450 (SMUGS5_08400) trxA 1747135..1747449 (-) 315 WP_002263363.1 thioredoxin -
  SMUGS5_RS08455 (SMUGS5_08405) mutS/mutS2 1747524..1749854 (-) 2331 WP_002274341.1 endonuclease MutS2 Machinery gene
  SMUGS5_RS08460 (SMUGS5_08410) - 1749922..1750467 (-) 546 WP_002263361.1 CvpA family protein -
  SMUGS5_RS08465 (SMUGS5_08415) - 1750464..1750769 (-) 306 WP_002263360.1 hypothetical protein -
  SMUGS5_RS08470 (SMUGS5_08420) rnhC 1750964..1751875 (+) 912 WP_002271343.1 ribonuclease HIII -
  SMUGS5_RS08475 (SMUGS5_08425) lepB 1751895..1752482 (+) 588 WP_002263358.1 signal peptidase I -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87749.18 Da        Isoelectric Point: 6.6680

>NTDB_id=43558 SMUGS5_RS08455 WP_002274341.1 1747524..1749854(-) (mutS/mutS2) [Streptococcus mutans GS-5]
MNTKILKALEFDKVKKQFAHFLQSEQGQMELNDLLPMTNQEKIERSFAEIADVAQIFQEYASFGFGHSQDISESLRRLEL
GADLNTQELLAVKRILQMSAELKDFYDNLENVDLQILDCLFEKVEMFPNLQGSLQAINDGGFIEDFASPELTKIRHHIHQ
NEQQIRQILQEMLKKQGDLLAENLIASRSGRSVLPVKNTYRHRIAGVIHDISASGNTVYIEPRAVVNLNEEMTQARADER
HEMTRILHDLSDRLRSQTDIIGNNAWLLGHIDFVRGKYLYMRENQASLPSLTTDQTIRLLSVRHPLLSNPIANDLHFEHD
TTAILITGPNTGGKTIMLKTLGITQLMAQSGLPILADEGSKVAVFKDIFADIGDEQSIEQSLSTFSSHMTHIVEILQKAN
KDSLVLFDELGAGTDPQEGAALAMSILEHLRLSDIKTMITTHYPELKAYGIETEFIENASMEFDMVTLSPTYHFMQGVPG
RSNAFEIARRLGLSEIIVAEAENLTNTDSDVNKIIERLENQTIESRRRLDNIREVEQENLKFNRAVKKLYNEFSHAQDKE
LRKAKLKAQEIVDKALAESDFILKNLQDKAQLKPHEIIEAKGKLKKLVPEIELSKNKVLKKAKKKRAAKVGDDIIVSSYG
QRGTLTKRFKDGRWEAQVGLIKMTLQESEFDLVKSDKAQASQKRQAHLVKRTSQKAPSARLDLRGKRYEEAMQELDEFID
QALLNNMAQVDIIHGIGTGVIRDGVTKYLRRNKQVKEFGYAPQNAGGSGATIVTFK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=43558 SMUGS5_RS08455 WP_002274341.1 1747524..1749854(-) (mutS/mutS2) [Streptococcus mutans GS-5]
ATGAATACAAAGATTTTAAAAGCCTTAGAATTTGATAAGGTTAAAAAGCAATTTGCTCATTTTTTGCAGAGTGAGCAAGG
GCAAATGGAATTAAACGATTTATTACCTATGACCAATCAGGAAAAAATTGAACGTTCTTTTGCCGAAATTGCAGATGTAG
CACAGATTTTTCAGGAGTATGCTTCCTTTGGCTTTGGGCACAGTCAGGATATTTCAGAAAGTTTACGTCGTTTAGAATTA
GGAGCGGATCTCAATACTCAAGAGCTTTTGGCTGTCAAACGTATTTTGCAGATGTCAGCAGAGCTCAAGGACTTTTATGA
TAATTTAGAAAATGTTGATTTGCAAATTTTGGATTGCTTATTTGAAAAGGTTGAAATGTTTCCTAATTTGCAAGGGAGTC
TACAAGCCATCAATGATGGTGGCTTTATTGAAGATTTTGCTAGTCCTGAATTAACTAAAATTCGTCATCATATTCACCAA
AATGAACAACAAATTCGTCAAATTCTTCAAGAAATGTTGAAGAAACAAGGTGATTTATTGGCTGAAAACCTTATTGCCAG
TCGCAGTGGTCGCAGTGTTCTTCCAGTGAAAAATACTTATCGTCATCGTATTGCAGGTGTTATTCATGATATTTCAGCTT
CAGGAAATACGGTTTACATTGAACCTCGAGCTGTTGTTAATTTAAATGAAGAGATGACTCAGGCGCGTGCAGACGAACGC
CATGAAATGACTCGCATTTTACATGATTTATCCGATAGGCTAAGATCACAAACAGATATTATTGGTAATAATGCTTGGTT
GCTTGGACATATTGATTTTGTTCGTGGGAAATACCTTTATATGAGAGAAAATCAAGCCAGTCTTCCTAGTTTAACAACGG
ATCAAACTATCCGTCTTTTGAGTGTACGTCATCCTCTGCTAAGTAATCCAATTGCCAATGATTTACATTTTGAACATGAT
ACAACAGCCATTTTAATTACAGGTCCTAATACGGGCGGTAAAACCATCATGTTAAAAACATTGGGAATAACACAACTGAT
GGCTCAGTCAGGTCTTCCTATTTTGGCTGATGAGGGAAGTAAGGTTGCTGTTTTTAAAGACATCTTTGCAGACATTGGTG
ATGAACAGTCCATTGAGCAAAGTTTATCCACTTTTTCAAGTCATATGACACATATTGTCGAAATTCTGCAAAAGGCCAAT
AAAGACAGCTTAGTCCTTTTTGATGAACTTGGTGCTGGTACGGATCCACAAGAAGGGGCAGCCTTGGCCATGAGTATTCT
GGAACATTTACGCTTATCAGATATTAAAACAATGATTACCACCCATTATCCAGAGCTCAAGGCCTATGGTATCGAAACAG
AATTTATTGAAAATGCGAGTATGGAATTTGATATGGTGACGCTCAGCCCCACCTATCATTTTATGCAAGGAGTACCGGGA
CGATCCAATGCTTTTGAGATTGCACGTCGTTTAGGTTTGTCTGAAATTATTGTTGCAGAAGCGGAAAATTTGACGAATAC
GGATTCAGATGTTAATAAAATTATCGAACGTTTGGAAAATCAAACCATTGAAAGTCGCAGACGTTTGGATAATATTCGTG
AAGTGGAGCAGGAAAATCTCAAATTTAATCGAGCCGTCAAAAAACTTTATAATGAATTCTCACATGCACAAGACAAAGAG
TTGCGTAAGGCCAAACTAAAGGCTCAAGAGATTGTTGACAAGGCTCTTGCAGAGAGTGATTTTATTCTCAAAAATCTTCA
AGACAAAGCACAACTTAAGCCCCATGAAATTATTGAAGCTAAAGGCAAGCTCAAGAAGTTGGTTCCCGAGATAGAGCTTT
CGAAAAATAAGGTTCTTAAAAAAGCTAAGAAGAAACGTGCTGCGAAAGTTGGAGATGATATTATTGTCAGCAGTTATGGG
CAAAGAGGAACGCTTACTAAGCGCTTCAAAGATGGTCGTTGGGAAGCACAAGTAGGGCTGATCAAAATGACTTTACAAGA
GTCAGAGTTTGATTTAGTGAAATCAGACAAAGCCCAAGCATCGCAGAAAAGACAAGCTCACCTTGTCAAAAGGACTTCTC
AAAAGGCTCCTAGTGCTAGACTTGATTTACGTGGCAAGCGTTATGAAGAAGCGATGCAAGAATTAGATGAATTCATTGAT
CAGGCACTCTTGAACAATATGGCTCAGGTTGACATCATCCATGGTATCGGAACTGGTGTTATCCGTGATGGCGTAACTAA
ATATCTTCGCCGTAATAAGCAAGTTAAGGAGTTTGGCTATGCTCCTCAAAATGCAGGTGGTTCGGGCGCTACAATCGTGA
CTTTCAAATAG

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(630-669)

Smr domain (Smr)

(701-776)

MutS domain V (MutS_V)

(324-505)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.594

100

0.402

Multiple sequence alignment