Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SMUGS5_RS08265 Genome accession   NC_018089
Coordinates   1707943..1708728 (-) Length   261 a.a.
NCBI ID   WP_002263472.1    Uniprot ID   P59388
Organism   Streptococcus mutans GS-5     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1702943..1713728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS08245 (SMUGS5_08180) gatA 1703486..1704952 (-) 1467 WP_002274738.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  SMUGS5_RS08250 (SMUGS5_08185) gatC 1704952..1705254 (-) 303 WP_002302577.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  SMUGS5_RS08255 (SMUGS5_08190) aspS 1705381..1707132 (-) 1752 WP_014835032.1 aspartate--tRNA ligase -
  SMUGS5_RS08260 (SMUGS5_08195) - 1707390..1707941 (-) 552 WP_002263473.1 cysteine hydrolase family protein -
  SMUGS5_RS08265 (SMUGS5_08200) codY 1707943..1708728 (-) 786 WP_002263472.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SMUGS5_RS08270 (SMUGS5_08205) - 1708837..1710051 (-) 1215 WP_002263471.1 pyridoxal phosphate-dependent aminotransferase -
  SMUGS5_RS08275 (SMUGS5_08210) - 1710228..1710764 (+) 537 WP_002263470.1 biotin transporter BioY -
  SMUGS5_RS08280 (SMUGS5_08215) - 1710862..1711311 (+) 450 WP_002263469.1 universal stress protein -
  SMUGS5_RS08285 (SMUGS5_08220) - 1711589..1712974 (-) 1386 WP_002268948.1 Cof-type HAD-IIB family hydrolase -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28970.13 Da        Isoelectric Point: 4.5032

>NTDB_id=43552 SMUGS5_RS08265 WP_002263472.1 1707943..1708728(-) (codY) [Streptococcus mutans GS-5]
MANLLSKTRRITSILQRSVESLQSDLPYNTIADQLAEIIDCNACIIDGSGIILGYAMKYKTNTDRVEEFFQAKKLPDDYV
KSASRIYDTEANLSVENDLTIFPIESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDKEFNDDDLILIEISSTVVGIQLLN
LQTENLEETIRKQTAINMAINTLSYSEMKAVAAILNELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKDYS

Nucleotide


Download         Length: 786 bp        

>NTDB_id=43552 SMUGS5_RS08265 WP_002263472.1 1707943..1708728(-) (codY) [Streptococcus mutans GS-5]
ATGGCTAATTTATTATCGAAAACGCGACGTATTACATCCATTTTACAACGCTCGGTTGAGAGCCTTCAAAGTGATTTGCC
TTATAATACGATTGCAGATCAATTGGCTGAAATTATTGATTGTAATGCTTGTATTATTGATGGTAGTGGTATTATTCTCG
GCTATGCTATGAAGTATAAAACCAATACAGATCGTGTTGAAGAATTTTTCCAAGCTAAAAAATTACCTGATGATTATGTA
AAATCGGCCAGCCGTATTTATGATACAGAAGCCAATCTGTCGGTTGAAAATGATTTGACCATTTTTCCAATTGAATCAAA
AGATATCTATCCTGATGGCTTGACGACTATTGCTCCCATCTATGGCGGCGGTATGCGTCTTGGTTCTCTTATTATCTGGC
GTAATGATAAAGAATTCAATGATGACGATTTGATTCTAATTGAGATTTCTTCTACTGTTGTTGGAATTCAATTATTGAAC
TTGCAGACAGAAAATCTTGAAGAAACAATTCGTAAGCAGACTGCTATTAATATGGCGATTAATACCTTGTCTTATTCAGA
AATGAAAGCTGTCGCAGCTATTCTCAATGAATTAGATGGCAATGAAGGTCGCTTGACCGCATCGGTTATTGCTGATCGTA
TCGGTATTACACGTAGCGTGATTGTTAATGCTCTTAGAAAGTTAGAAAGTGCCGGTATTATTGAAAGTCGTTCCTTAGGT
ATGAAAGGTACTTATCTCAAAGTTATTAATGAAGGTATTTTTGATAAATTAAAGGACTATAGTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59388

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.37

98.467

0.644
  codY Bacillus subtilis subsp. subtilis str. 168

48.047

98.084

0.471

Multiple sequence alignment