Detailed information NTG0435370

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: HEQ84_RS05495
• Genome accession: NZ_CP050870
• Coordinates: 1048605..1049486 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CS6
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1043605..1054486

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HEQ84_RS05470 (HEQ84_05470)	vicR	1044309..1045016 (-)	708	WP_011681206.1	response regulator YycF	Regulator
HEQ84_RS05475 (HEQ84_05475)	-	1045543..1046310 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
HEQ84_RS05480 (HEQ84_05480)	-	1046322..1047155 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
HEQ84_RS05485 (HEQ84_05485)	-	1047173..1047871 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
HEQ84_RS05490 (HEQ84_05490)	-	1047883..1048533 (+)	651	WP_024704148.1	amino acid ABC transporter permease	-
HEQ84_RS05495 (HEQ84_05495)	endA	1048605..1049486 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
HEQ84_RS05500 (HEQ84_05500)	-	1049548..1049736 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
HEQ84_RS05505 (HEQ84_05505)	murA	1049738..1051009 (-)	1272	WP_024704149.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
HEQ84_RS05510 (HEQ84_05510)	-	1051079..1051315 (-)	237	WP_002946959.1	DUF1146 family protein	-
HEQ84_RS05515 (HEQ84_05515)	galE	1051504..1052517 (-)	1014	WP_014621668.1	UDP-glucose 4-epimerase GalE	-
HEQ84_RS05520 (HEQ84_05520)	-	1052532..1052966 (-)	435	WP_231107205.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=435370 HEQ84_RS05495 WP_011681210.1 1048605..1049486(-) (endA) [Streptococcus thermophilus strain CS6]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=435370 HEQ84_RS05495 WP_011681210.1 1048605..1049486(-) (endA) [Streptococcus thermophilus strain CS6]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594