Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SCIM_RS07160 Genome accession   NC_018073
Coordinates   1464273..1465061 (-) Length   262 a.a.
NCBI ID   WP_003035535.1    Uniprot ID   I0SFK2
Organism   Streptococcus intermedius JTH08     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1459273..1470061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS07135 (SCIM_1279) gatA 1459745..1461211 (-) 1467 WP_003075815.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  SCIM_RS07140 (SCIM_1280) gatC 1461211..1461513 (-) 303 WP_003074461.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  SCIM_RS07145 (SCIM_1281) aspS 1461578..1463319 (-) 1742 Protein_1396 aspartate--tRNA ligase -
  SCIM_RS07155 (SCIM_1283) - 1463698..1464273 (-) 576 WP_003074458.1 cysteine hydrolase family protein -
  SCIM_RS07160 (SCIM_1284) codY 1464273..1465061 (-) 789 WP_003035535.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SCIM_RS07165 (SCIM_1285) - 1465223..1466437 (-) 1215 WP_003075849.1 pyridoxal phosphate-dependent aminotransferase -
  SCIM_RS07170 (SCIM_1286) - 1466590..1467042 (+) 453 WP_003028799.1 universal stress protein -
  SCIM_RS07175 (SCIM_1288) - 1467088..1468476 (-) 1389 WP_003074451.1 Cof-type HAD-IIB family hydrolase -
  SCIM_RS07180 (SCIM_1289) - 1468541..1469503 (+) 963 WP_003075884.1 asparaginase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29724.06 Da        Isoelectric Point: 5.0797

>NTDB_id=43336 SCIM_RS07160 WP_003035535.1 1464273..1465061(-) (codY) [Streptococcus intermedius JTH08]
MANLLAKTRKITSILRRSDERLQDELPYNAITQQLAEIMDCNACIVNSKGRLLGYFMRYKTNNDRVEAFYQTKIFPEEYV
RTANLMYDTEANLPVNHDLSIFPIETKDEFPDGLTTISPIHVSGIRLGTLIVWRNDKEFDDDDLILVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELSGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLIPDIFEEIKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=43336 SCIM_RS07160 WP_003035535.1 1464273..1465061(-) (codY) [Streptococcus intermedius JTH08]
ATGGCAAACTTATTAGCAAAAACAAGAAAAATAACATCTATTTTGCGTCGTTCAGATGAGCGATTGCAGGATGAACTACC
TTATAATGCAATTACCCAACAATTAGCTGAAATTATGGATTGCAATGCTTGTATTGTAAATAGCAAGGGTCGTCTTTTGG
GGTATTTCATGCGCTACAAGACAAACAATGATCGTGTGGAAGCATTTTATCAAACGAAAATCTTCCCAGAAGAGTATGTT
CGCACCGCAAATTTGATGTATGATACTGAGGCCAATCTTCCAGTCAATCATGATTTATCTATTTTTCCTATTGAGACAAA
AGATGAATTTCCAGATGGCTTGACGACAATTTCACCGATTCATGTTTCTGGGATTCGTTTAGGGACATTGATTGTTTGGC
GCAATGATAAAGAATTTGACGATGATGATTTGATCTTGGTTGAAATTGCAAGTACAGTGGTTGGTATTCAGCTACTCAAC
TTCCAACGAGAAGAAGATGAAAAAAATATTCGACGTCGAACAGCTGTAACTATGGCTGTAAATACTTTGTCTTATTCAGA
ATTACGAGCTGTTTCTGCTATTTTAGGTGAATTAAGCGGCAATGAAGGGCAGCTAACAGCTTCAGTGATTGCAGATCGTA
TTGGCATTACGCGCTCAGTGATTGTCAATGCTCTACGTAAACTAGAAAGTGCAGGCATTATCGAAAGTCGTTCTCTAGGA
ATGAAAGGAACCTATCTTAAAGTTCTTATCCCTGATATCTTTGAAGAGATTAAAAAGCGAGATTACTGA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SFK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

61.832

100

0.618
  codY Bacillus subtilis subsp. subtilis str. 168

50

93.893

0.469

Multiple sequence alignment