Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   SCIM_RS01150 Genome accession   NC_018073
Coordinates   229837..232170 (+) Length   777 a.a.
NCBI ID   WP_003077475.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 224837..237170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS01130 (SCIM_0192) lepB 227333..227947 (-) 615 WP_003077544.1 signal peptidase I -
  SCIM_RS01135 (SCIM_0193) rnhC 227951..228841 (-) 891 WP_003077692.1 ribonuclease HIII -
  SCIM_RS01140 (SCIM_0194) - 228927..229232 (+) 306 WP_003074635.1 hypothetical protein -
  SCIM_RS01145 (SCIM_0195) - 229229..229777 (+) 549 WP_003070931.1 CvpA family protein -
  SCIM_RS01150 (SCIM_0196) mutS/mutS2 229837..232170 (+) 2334 WP_003077475.1 endonuclease MutS2 Machinery gene
  SCIM_RS01155 (SCIM_0197) - 232232..233653 (+) 1422 WP_003077740.1 C69 family dipeptidase -
  SCIM_RS01160 (SCIM_0198) trxA 233758..234072 (+) 315 WP_003074629.1 thioredoxin -
  SCIM_RS01165 (SCIM_0199) - 234233..234751 (-) 519 WP_003074627.1 DUF4865 family protein -
  SCIM_RS01170 (SCIM_0200) - 234860..235606 (+) 747 WP_003077559.1 LysR family transcriptional regulator -
  SCIM_RS01175 (SCIM_0201) - 235707..236114 (+) 408 WP_003077720.1 polyketide cyclase -

Sequence

Protein


Download         Length: 777 a.a.        Molecular weight: 87641.35 Da        Isoelectric Point: 6.3128

>NTDB_id=43277 SCIM_RS01150 WP_003077475.1 229837..232170(+) (mutS/mutS2) [Streptococcus intermedius JTH08]
MNRKILETLEFGKIKALFEPYLLTEQGRLELGQLFPSNKQERLETAFLEMTDMQQIFVQRPHFSLAATQDITGLTKRLEL
EGDLNIEEFLALKRILTVTQELTDFYDKLENVDLQRLNRLFEKLLAFPNLQGLLQAINEGGFVESFASDNLARIRRKIQE
NEVQVRDILQDILKTKGDMLVDQVVASRNGRNVLPVKNTFRNRISGVVHDISASGNTVYIEPRAVVNLNEEITNAQADER
HEILRILQELSDRIRPHIAEIANNAWIIGHLDLVRAKVCFMQERGAVVPMLSDSKDIRLLHVTHPLIENAVANDLYFASD
LTEIVITGPNTGGKTIMLKTLGLAQLMAQSGLPILADNGSRVGIFDQIFADIGDEQSIEQSLSTFSSHMTNIVAILEQVD
ENALVLLDELGAGTDPQEGAALAMAILEDLRLRQVKTMATTHYPELKAYGIEMAGVQNASMEFDTASLRPTYRFMQGVPG
RSNALEIARRLGLSELVVRHAQEQTNTDSDVNRIIERLEEQTLESRKRLDNIREVEQENLKFNRALKKLYNEFNREKETE
LNKARLEAQEIVDLALSESESILKNLHDKSSLKPHEIIEAKAQLKKLAPETVDLSKNKVLKQAKKNRAPKVGDDILVTSY
GQRGTLVKQLKDGRWEAQVGLIKMTLEEQEFNLLKAEKEQQPKRKQVNVVKRTTTSGPRARLDLRGKRYEEAMQELDAFI
DQALLNNMAQVDIIHGIGTGVIREGVTKYLRRNKHVKSFGYAPQNAGGSGATIVVFK

Nucleotide


Download         Length: 2334 bp        

>NTDB_id=43277 SCIM_RS01150 WP_003077475.1 229837..232170(+) (mutS/mutS2) [Streptococcus intermedius JTH08]
ATGAATAGAAAAATTTTAGAAACATTAGAATTTGGGAAAATCAAGGCACTCTTTGAACCCTATCTGTTAACAGAACAAGG
CCGTTTAGAGCTAGGACAGCTTTTTCCATCTAATAAACAGGAACGGTTGGAGACAGCATTTTTAGAAATGACGGACATGC
AGCAGATTTTTGTGCAGCGTCCGCATTTCAGCTTGGCTGCGACTCAAGATATTACTGGACTGACCAAGCGTTTGGAGCTG
GAAGGCGACTTAAATATTGAAGAATTTCTTGCTCTGAAGCGTATTTTAACTGTCACGCAAGAATTAACTGATTTCTATGA
TAAGTTGGAAAATGTTGATTTGCAACGCTTGAACCGTCTTTTTGAAAAATTATTGGCTTTTCCTAACCTGCAAGGATTAC
TGCAAGCCATCAATGAGGGTGGATTTGTCGAAAGCTTTGCGAGTGACAATTTAGCTCGCATTCGTCGGAAAATTCAAGAA
AATGAAGTTCAAGTAAGAGATATTCTGCAAGATATTCTCAAAACGAAGGGCGATATGTTGGTAGATCAAGTAGTAGCTAG
TCGAAATGGTCGCAATGTTTTGCCAGTTAAAAATACATTTCGTAATCGGATTTCAGGCGTGGTACATGATATTTCTGCTA
GTGGAAATACAGTATATATCGAGCCGAGGGCAGTAGTCAACCTCAACGAAGAAATCACCAATGCACAGGCAGACGAGCGT
CATGAGATTCTACGTATCTTGCAAGAGTTGTCCGACCGAATACGTCCTCATATTGCTGAAATTGCTAATAACGCTTGGAT
TATTGGGCATTTGGATCTAGTTCGGGCGAAAGTGTGTTTTATGCAGGAGAGAGGCGCGGTGGTGCCGATGCTGTCTGATA
GTAAGGATATTCGCCTGCTCCATGTTACTCATCCTTTGATAGAAAATGCAGTGGCTAATGATTTGTACTTTGCGTCGGAT
TTAACGGAAATCGTCATTACTGGTCCTAACACAGGTGGGAAGACAATTATGCTGAAGACCTTGGGCTTGGCTCAACTCAT
GGCGCAGTCTGGTCTGCCTATTTTGGCGGATAATGGTAGTCGAGTGGGGATTTTTGACCAAATTTTTGCCGACATCGGAG
ATGAGCAGTCTATTGAGCAGAGCTTATCGACTTTCTCTAGCCACATGACTAATATTGTTGCCATTTTAGAGCAAGTAGAC
GAAAATGCTCTGGTACTTCTGGATGAGCTTGGAGCTGGAACCGATCCGCAGGAGGGTGCAGCTCTTGCGATGGCAATCCT
TGAAGACCTGCGACTGCGGCAGGTCAAGACAATGGCAACGACTCATTACCCAGAGCTTAAGGCTTATGGGATTGAAATGG
CTGGCGTACAAAATGCTAGCATGGAGTTTGATACGGCAAGTCTAAGACCAACTTATCGCTTTATGCAGGGGGTGCCAGGG
CGTTCTAATGCCCTTGAAATTGCTCGCCGTTTGGGCTTGTCGGAACTTGTCGTTCGCCATGCCCAAGAGCAGACCAACAC
GGACAGCGATGTCAATCGGATCATTGAGAGACTGGAGGAGCAAACGCTGGAAAGCCGCAAGCGCTTAGACAATATCCGTG
AGGTTGAGCAGGAAAATCTCAAATTTAACCGAGCACTCAAAAAACTTTACAATGAGTTTAACCGAGAGAAAGAAACCGAA
CTCAATAAGGCACGGTTGGAAGCTCAGGAAATTGTTGATCTGGCTTTGTCAGAGAGTGAGAGCATTCTCAAAAATCTCCA
TGATAAGTCTAGTCTCAAACCGCATGAGATTATCGAAGCTAAGGCCCAGCTTAAAAAGTTGGCGCCAGAAACCGTTGATT
TATCAAAGAACAAGGTGCTCAAGCAGGCCAAGAAAAATCGTGCGCCCAAGGTGGGAGATGATATTCTGGTAACCAGCTAT
GGTCAGCGAGGAACCTTGGTCAAGCAGCTCAAGGACGGCCGTTGGGAGGCTCAGGTCGGTCTTATCAAGATGACTCTAGA
AGAGCAGGAATTTAATCTTCTAAAGGCTGAAAAGGAGCAGCAGCCTAAGCGCAAGCAGGTCAATGTGGTGAAACGAACAA
CCACAAGCGGACCAAGAGCTAGACTGGATTTGCGAGGCAAGCGTTATGAAGAAGCTATGCAAGAGCTGGACGCCTTTATT
GATCAGGCTCTCCTCAACAACATGGCTCAGGTTGATATTATTCACGGTATCGGGACCGGTGTGATCCGTGAAGGTGTGAC
TAAGTACCTCCGCCGCAACAAGCACGTCAAGTCCTTTGGTTATGCTCCGCAAAATGCCGGTGGCAGCGGCGCGACGATTG
TGGTGTTTAAGTGA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(702-777)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-668)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.29

100

0.399

Multiple sequence alignment