Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   ILP78_RS09435 Genome accession   NZ_CP062465
Coordinates   1889095..1891443 (-) Length   782 a.a.
NCBI ID   WP_001249283.1    Uniprot ID   -
Organism   Staphylococcus aureus strain MRSA - AMRF 6     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1884095..1896443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ILP78_RS09415 (ILP78_09415) - 1885564..1886178 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  ILP78_RS09420 (ILP78_09420) uvrC 1886502..1888283 (-) 1782 WP_000390533.1 excinuclease ABC subunit UvrC Machinery gene
  ILP78_RS09425 (ILP78_09425) - 1888473..1888545 (+) 73 Protein_1831 hypothetical protein -
  ILP78_RS09430 (ILP78_09430) trxA 1888608..1888922 (-) 315 WP_001018928.1 thioredoxin -
  ILP78_RS09435 (ILP78_09435) mutS/mutS2 1889095..1891443 (-) 2349 WP_001249283.1 endonuclease MutS2 Machinery gene
  ILP78_RS09440 (ILP78_09440) polX 1891453..1893165 (-) 1713 WP_000161946.1 DNA polymerase/3'-5' exonuclease PolX -
  ILP78_RS09445 (ILP78_09445) - 1893238..1893759 (-) 522 WP_000234075.1 CvpA family protein -
  ILP78_RS09450 (ILP78_09450) zapA 1893767..1894026 (-) 260 Protein_1836 cell division protein ZapA -
  ILP78_RS09455 (ILP78_09455) rnhC 1894396..1895334 (+) 939 WP_001284281.1 ribonuclease HIII -

Sequence

Protein


Download         Length: 782 a.a.        Molecular weight: 88723.31 Da        Isoelectric Point: 6.1373

>NTDB_id=431067 ILP78_RS09435 WP_001249283.1 1889095..1891443(-) (mutS/mutS2) [Staphylococcus aureus strain MRSA - AMRF 6]
MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADI
GGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRS
KISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISR
LRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEDRTVYLPKAYHPLLNRETVVA
NTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNI
VEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTY
KLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRIETQRLELDRLVKEAEQVHDDLSKQYQ
QFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIV
AGDEVKVLSYGQKGEVLEIFNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIE
LDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK

Nucleotide


Download         Length: 2349 bp        

>NTDB_id=431067 ILP78_RS09435 WP_001249283.1 1889095..1891443(-) (mutS/mutS2) [Staphylococcus aureus strain MRSA - AMRF 6]
ATGAGACAAAAAACATTAGACGTCTTAGAATTCGAAAAAATAAAATCACTCGTTGCCAATGAAACTATTAGTGACTTAGG
CTTGGAAAAGGTCAATCAAATGATGCCAGCTACTAATTTTGAAACGGTTGTTTTTCAAATGGAAGAAACGGATGAGATTG
CTCAAATCTATAATAAGCATCGTTTACCAAGCTTGAGTGGCTTATCTAAAGTATCAGCATTCATTCATCGCGCTGATATT
GGCGGCGTTTTAAATGTATCAGAGCTTAACTTGATAAAAAGATTAATTCAAGTACAAAATCAATTCAAGACATTTTATAA
TCAATTGGTTGAAGAAGATGAAGGTGTTAAATACCCAATATTAGATGACAAGATGAATCAATTACCTGTGTTAACTGATC
TTTTTCAACAAATAAATGAAACATGCGATACGTATGATTTATATGATAATGCGAGTTATGAATTGCAAGGGATTAGAAGT
AAAATTTCTAGCACGAATCAACGTATTAGACAAAATTTGGACCGTATTGTTAAAAGCCAAGCAAATCAGAAAAAATTATC
AGATGCTATTGTAACAGTTAGGAATGAAAGAAACGTTATACCTGTCAAAGCTGAATATCGACAAGATTTTAATGGGATTG
TACATGATCAATCTGCTTCAGGACAAACATTGTATATTGAGCCATCATCAGTTGTTGAAATGAATAATCAAATTAGTCGA
TTACGTCATGACGAAGCAATTGAAAAAGAACGCATTTTAACGCAACTAACTGGTTATGTGGCTGCGGACAAAGATGCACT
ACTTGTGGCAGAACAAGTCATGGGTCAGTTAGATTTTTTAATCGCAAAAGCGAGATATAGTAGAAGTATTAAAGGAACAA
AGCCGATATTTAAAGAGGACCGTACTGTATATTTACCTAAAGCATACCATCCATTATTAAATCGTGAGACTGTTGTAGCT
AATACCATCGAATTTATGGAAGATATTGAAACGGTAATTATTACAGGACCGAATACAGGTGGTAAAACTGTAACATTAAA
AACATTAGGTTTAATTATTGTTATGGCTCAATCAGGATTGTTGATTCCCACACTTGATGGTAGTCAGTTAAGTGTATTTA
AAAATGTATATTGCGATATCGGAGATGAACAATCAATAGAACAATCATTATCAACTTTTTCATCTCATATGACGAATATA
GTTGAAATTTTAAAGCATGCAGACAAACATAGTTTAGTTTTATTTGATGAATTAGGTGCAGGTACAGATCCAAGTGAAGG
TGCTGCATTAGCAATGAGCATTTTAGATCATGTTAGAAAAATTGGTTCTCTAGTAATGGCAACGACGCACTATCCTGAAC
TTAAAGCATATAGTTATAATCGAGAAGGCGTTATGAATGCGAGTGTAGAATTTGATGTAGATACTTTGAGTCCAACGTAT
AAGTTATTAATGGGTGTGCCGGGTCGTTCAAATGCTTTTGACATTTCTAAAAAGTTAGGTCTTAGTTTGAATATTATTAA
TAAGGCTAAGACGATGATTGGTACTGATGAAAAAGAAATAAATGAAATGATTGAATCATTAGAGCGTAATTACAAACGTA
TAGAGACACAGAGGTTAGAACTGGACCGTCTTGTAAAAGAAGCGGAGCAAGTGCATGATGATTTATCTAAGCAGTATCAA
CAATTCCAAAATTATGAAAAGTCTCTAATAGAGGAAGCGAAAGAAAAAGCAAATCAGAAGATTAAAGCTGCAACAAAAGA
AGCTGACGATATTATTAAAGACTTAAGACAATTGCGTGAACAAAAAGGTGCAGATGTTAAAGAACATGAATTGATTGATA
AGAAGAAACGATTAGATGATCATTATGAAGCGAAATCTATAAAGCAAAATGTACAAAAGCAAAAATACGATAAAATTGTT
GCTGGTGATGAAGTAAAAGTATTATCTTACGGTCAAAAGGGTGAAGTTTTAGAAATTTTCAATGATGAAGAAGCAATTGT
TCAAATGGGAATTATTAAAATGAAGTTACCTATTGAAGATTTAGAGAAAAAACAAAAAGAAAAAGTTAAGCCAACGAAAA
TGGTTACACGTCAAAATCGTCAAACAATTAAAACTGAACTTGACTTACGAGGCTATCGTTATGAGGATGCTTTAATTGAA
CTAGATCAATATTTAGATCAAGCTGTTTTAAGTAATTACGAACAAGTTTATATCATTCATGGTAAAGGTACAGGTGCACT
TCAAAAAGGTGTACAACAACATTTGAAAAAGCATAAAAGTGTTAGTGACTTTAGAGGTGGTATGCCAAGCGAAGGTGGAT
TTGGCGTTACCGTTGCAACACTAAAATAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(332-512)

MutS2 and Smr-associated SH3 domain (MSSS)

(641-681)

Smr domain (Smr)

(707-782)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

49.937

100

0.504