Detailed information NTG0431042

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: HB753_RS02500
• Genome accession: NZ_CP050270
• Coordinates: 480899..481780 (+)
• Length: 293 a.a.
• NCBI ID: WP_002264825.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain S4
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 475899..486780

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HB753_RS02470 (HB753_02470)	-	476082..476960 (+)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-
HB753_RS02475 (HB753_02475)	atpD	476986..478392 (+)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
HB753_RS02480 (HB753_02480)	-	478406..478822 (+)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
HB753_RS02485 (HB753_02485)	-	479096..479329 (+)	234	WP_002285829.1	DUF1146 family protein	-
HB753_RS02490 (HB753_02490)	murA	479395..480666 (+)	1272	WP_002262937.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
HB753_RS02495 (HB753_02495)	-	480669..480857 (+)	189	WP_002264826.1	DNA-directed RNA polymerase subunit beta	-
HB753_RS02500 (HB753_02500)	endA	480899..481780 (+)	882	WP_002264825.1	DNA/RNA non-specific endonuclease	Machinery gene
HB753_RS02505 (HB753_02505)	-	481848..482498 (-)	651	WP_002262934.1	amino acid ABC transporter permease	-
HB753_RS02510 (HB753_02510)	-	482513..483217 (-)	705	WP_002266143.1	amino acid ABC transporter permease	-
HB753_RS02515 (HB753_02515)	-	483235..484047 (-)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
HB753_RS02520 (HB753_02520)	-	484044..484826 (-)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
HB753_RS02525 (HB753_02525)	vicR	485179..485886 (+)	708	WP_002262930.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32157.75 Da
• Isoelectric Point: 9.5337

>NTDB_id=431042 HB753_RS02500 WP_002264825.1 480899..481780(+) (endA) [Streptococcus mutans strain S4]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYANNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=431042 HB753_RS02500 WP_002264825.1 480899..481780(+) (endA) [Streptococcus mutans strain S4]
ATGACTAGAAAAACGAACAAGTCTCAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAATAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCGGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (103-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	64.103	79.863	0.512
endA	Streptococcus pneumoniae D39	64.103	79.863	0.512
endA	Streptococcus pneumoniae R6	64.103	79.863	0.512
endA	Streptococcus pneumoniae TIGR4	64.103	79.863	0.512