Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   D39N_RS07065 Genome accession   NZ_CP061208
Coordinates   1430682..1431470 (-) Length   262 a.a.
NCBI ID   WP_000940734.1    Uniprot ID   Q8DP01
Organism   Streptococcus pneumoniae strain D39_P0     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1425682..1436470
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D39N_RS07035 (D39N_01418) - 1426668..1427180 (-) 513 WP_001049323.1 adenine phosphoribosyltransferase -
  D39N_RS07040 (D39N_01419) - 1427268..1428026 (-) 759 WP_001287230.1 class I SAM-dependent methyltransferase -
  D39N_RS07045 - 1428234..1428380 (+) 147 WP_000403102.1 hypothetical protein -
  D39N_RS07050 (D39N_01420) ugpC 1428527..1429657 (-) 1131 WP_000229959.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
  D39N_RS07060 (D39N_01422) - 1430107..1430682 (-) 576 WP_000158722.1 isochorismatase family cysteine hydrolase -
  D39N_RS07065 (D39N_01423) codY 1430682..1431470 (-) 789 WP_000940734.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  D39N_RS07070 (D39N_01424) - 1431734..1433308 (-) 1575 WP_000671113.1 DEAD/DEAH box helicase -
  D39N_RS07075 (D39N_01425) - 1433507..1434733 (-) 1227 WP_000841575.1 OFA family MFS transporter -
  D39N_RS07080 (D39N_01426) - 1434923..1436239 (+) 1317 WP_000958943.1 FAD-containing oxidoreductase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29756.11 Da        Isoelectric Point: 5.4646

>NTDB_id=420968 D39N_RS07065 WP_000940734.1 1430682..1431470(-) (codY) [Streptococcus pneumoniae strain D39_P0]
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=420968 D39N_RS07065 WP_000940734.1 1430682..1431470(-) (codY) [Streptococcus pneumoniae strain D39_P0]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTCCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTGCCTGTTGAGCATGATATGAGTATTTTCCCTGTTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGCAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DP01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

48.374

93.893

0.454