Detailed information NTG0420322

Bioinformatically predicted

Overview

• Name: mutS/mutS2
• Type: Machinery gene
• Locus tag: IB937_RS01705
• Genome accession: NZ_CP061132
• Coordinates: 322185..324524 (+)
• Length: 779 a.a.
• NCBI ID: WP_021299031.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain BSAC_bs1388 isolate Invasive disease
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 317185..329524

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IB937_RS01685 (IB937_01685)	lepB	319517..320110 (-)	594	WP_136278208.1	signal peptidase I	-
IB937_RS01690 (IB937_01690)	rnhC	320121..321023 (-)	903	WP_011528946.1	ribonuclease HIII	-
IB937_RS01695 (IB937_01695)	-	321180..321488 (+)	309	WP_002993251.1	hypothetical protein	-
IB937_RS01700 (IB937_01700)	-	321491..322036 (+)	546	WP_002983087.1	CvpA family protein	-
IB937_RS01705 (IB937_01705)	mutS/mutS2	322185..324524 (+)	2340	WP_021299031.1	endonuclease MutS2	Machinery gene
IB937_RS01710 (IB937_01710)	-	324528..325028 (+)	501	WP_021299043.1	phosphatase PAP2 family protein	-
IB937_RS01715 (IB937_01715)	trxA	325091..325423 (+)	333	WP_257577416.1	thioredoxin	-
IB937_RS01720 (IB937_01720)	-	325475..326062 (-)	588	WP_011528942.1	helix-turn-helix domain-containing protein	-
IB937_RS01725 (IB937_01725)	mutY	326239..327393 (-)	1155	WP_002988276.1	A/G-specific adenine glycosylase	-
IB937_RS01730 (IB937_01730)	-	327561..327854 (+)	294	WP_002983113.1	hypothetical protein	-
IB937_RS01735 (IB937_01735)	rpsF	328027..328317 (+)	291	WP_002983117.1	30S ribosomal protein S6	-
IB937_RS01740 (IB937_01740)	ssb	328339..328830 (+)	492	WP_002983122.1	single-stranded DNA-binding protein	Machinery gene
IB937_RS01745 (IB937_01745)	rpsR	328994..329233 (+)	240	WP_002983142.1	30S ribosomal protein S18	-

Sequence

Protein

• Length: 779 a.a.
• Molecular weight: 87795.07 Da
• Isoelectric Point: 6.6550

>NTDB_id=420322 IB937_RS01705 WP_021299031.1 322185..324524(+) (mutS/mutS2) [Streptococcus pyogenes strain BSAC_bs1388 isolate Invasive disease]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPKLERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHTFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
RNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEAAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide

• Length: 2340 bp

>NTDB_id=420322 IB937_RS01705 WP_021299031.1 322185..324524(+) (mutS/mutS2) [Streptococcus pyogenes strain BSAC_bs1388 isolate Invasive disease]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
ACAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAAAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAGAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACACATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCAACGATACCTAAGATCTCTGATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTTTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CGCAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCTATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAAACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGTCCTACGTATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAATCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGCCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCACCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTAGCCTCGTTAGAGTTCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGCAGCAATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGTATTGGTACAGGCGTTATTCGTGAGGG
AGTGACAAAATATCTTCGTCGTAATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGTGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

• Smr domain (Smr) (704-778)

• MutS domain V (MutS_V) (324-505)

• MutS2 and Smr-associated SH3 domain (MSSS) (633-669)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mutS/mutS2	Bacillus subtilis subsp. subtilis str. 168	40.633	100	0.412