Detailed information NTG0419499

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: IBB94_RS07705
• Genome accession: NZ_CP061024
• Coordinates: 1500939..1501724 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain 13498
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1495939..1506724

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBB94_RS07670 (IBB94_07680)	gatC	1496002..1496304 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
IBB94_RS07675 (IBB94_07685)	-	1496444..1496698 (-)	255	WP_095559434.1	glycosyltransferase	-
IBB94_RS07680 (IBB94_07690)	-	1496711..1496920 (-)	210	WP_080998437.1	glycosyltransferase	-
IBB94_RS07685 (IBB94_07695)	-	1497236..1498680 (-)	1445	Protein_1478	6-phospho-beta-glucosidase	-
IBB94_RS07690 (IBB94_07700)	msrA	1498833..1499342 (-)	510	WP_041827375.1	peptide-methionine (S)-S-oxide reductase MsrA	-
IBB94_RS07695 (IBB94_07705)	-	1499354..1500202 (-)	849	WP_041828318.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
IBB94_RS07700 (IBB94_07710)	-	1500325..1500876 (-)	552	WP_084829819.1	isochorismatase family cysteine hydrolase	-
IBB94_RS07705 (IBB94_07715)	codY	1500939..1501724 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
IBB94_RS07710 (IBB94_07720)	-	1501984..1503198 (-)	1215	WP_011226456.1	pyridoxal phosphate-dependent aminotransferase	-
IBB94_RS07715 (IBB94_07725)	-	1503553..1504005 (+)	453	WP_002946987.1	universal stress protein	-
IBB94_RS10105	-	1504182..1504756 (+)	575	Protein_1485	IS30 family transposase	-
IBB94_RS07720 (IBB94_07730)	-	1504828..1505001 (-)	174	WP_011681546.1	hypothetical protein	-
IBB94_RS07725 (IBB94_07735)	-	1505062..1505436 (-)	375	WP_011681547.1	membrane protein	-
IBB94_RS07730 (IBB94_07740)	pflA	1505648..1506448 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=419499 IBB94_RS07705 WP_002951720.1 1500939..1501724(-) (codY) [Streptococcus thermophilus strain 13498]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=419499 IBB94_RS07705 WP_002951720.1 1500939..1501724(-) (codY) [Streptococcus thermophilus strain 13498]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGTCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502