Detailed information NTG0419296

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: IBB93_RS07795
• Genome accession: NZ_CP061022
• Coordinates: 1508688..1509473 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain 24738
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1503688..1514473

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBB93_RS07760 (IBB93_07810)	gatC	1503749..1504051 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
IBB93_RS07765 (IBB93_07815)	-	1504226..1504444 (-)	219	WP_242683841.1	glycosyltransferase	-
IBB93_RS10315	-	1504383..1504547 (-)	165	WP_242681665.1	glycosyltransferase	-
IBB93_RS07775 (IBB93_07825)	-	1504984..1506428 (-)	1445	Protein_1491	6-phospho-beta-glucosidase	-
IBB93_RS07780 (IBB93_07830)	msrA	1506581..1507090 (-)	510	WP_041827375.1	peptide-methionine (S)-S-oxide reductase MsrA	-
IBB93_RS07785 (IBB93_07835)	-	1507102..1507950 (-)	849	Protein_1493	MetQ/NlpA family ABC transporter substrate-binding protein	-
IBB93_RS07790 (IBB93_07840)	-	1508074..1508625 (-)	552	WP_002946999.1	isochorismatase family cysteine hydrolase	-
IBB93_RS07795 (IBB93_07845)	codY	1508688..1509473 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
IBB93_RS07800 (IBB93_07850)	-	1509733..1510947 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
IBB93_RS07805 (IBB93_07855)	-	1511302..1511754 (+)	453	WP_002946987.1	universal stress protein	-
IBB93_RS07810 (IBB93_07860)	-	1511934..1512505 (+)	572	Protein_1498	IS30 family transposase	-
IBB93_RS07815 (IBB93_07865)	-	1512577..1512750 (-)	174	WP_011681546.1	hypothetical protein	-
IBB93_RS07820 (IBB93_07870)	-	1512811..1513185 (-)	375	WP_011681547.1	membrane protein	-
IBB93_RS07825 (IBB93_07875)	pflA	1513397..1514197 (-)	801	WP_071417327.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=419296 IBB93_RS07795 WP_002951720.1 1508688..1509473(-) (codY) [Streptococcus thermophilus strain 24738]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=419296 IBB93_RS07795 WP_002951720.1 1508688..1509473(-) (codY) [Streptococcus thermophilus strain 24738]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502