Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   H7786_RS07630 Genome accession   NZ_CP060649
Coordinates   1530213..1532552 (-) Length   779 a.a.
NCBI ID   WP_030126291.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY270     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1525213..1537552
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7786_RS07590 (H7786_07645) rpsR 1525509..1525748 (-) 240 WP_002983142.1 30S ribosomal protein S18 -
  H7786_RS07595 (H7786_07650) ssbA 1525913..1526404 (-) 492 WP_002993238.1 single-stranded DNA-binding protein Machinery gene
  H7786_RS07600 (H7786_07655) rpsF 1526426..1526716 (-) 291 WP_002983117.1 30S ribosomal protein S6 -
  H7786_RS07605 (H7786_07660) - 1526889..1527182 (-) 294 WP_002983113.1 hypothetical protein -
  H7786_RS07610 (H7786_07665) mutY 1527350..1528504 (+) 1155 WP_168388902.1 A/G-specific adenine glycosylase -
  H7786_RS07615 (H7786_07670) - 1528681..1529262 (+) 582 WP_030126292.1 helix-turn-helix domain-containing protein -
  H7786_RS07620 (H7786_07675) trxA 1529314..1529646 (-) 333 WP_001932060.1 thioredoxin -
  H7786_RS07625 (H7786_07680) - 1529709..1530209 (-) 501 WP_015055998.1 phosphatase PAP2 family protein -
  H7786_RS07630 (H7786_07685) mutS/mutS2 1530213..1532552 (-) 2340 WP_030126291.1 endonuclease MutS2 Machinery gene
  H7786_RS07635 (H7786_07690) - 1532701..1533246 (-) 546 WP_002983087.1 CvpA family protein -
  H7786_RS07640 (H7786_07695) - 1533249..1533557 (-) 309 WP_002993251.1 hypothetical protein -
  H7786_RS07645 (H7786_07700) rnhC 1533714..1534616 (+) 903 WP_030126290.1 ribonuclease HIII -
  H7786_RS07650 (H7786_07705) lepB 1534627..1535220 (+) 594 WP_002983074.1 signal peptidase I -

Sequence

Protein


Download         Length: 779 a.a.        Molecular weight: 87855.08 Da        Isoelectric Point: 6.5168

>NTDB_id=416580 H7786_RS07630 WP_030126291.1 1530213..1532552(-) (mutS/mutS2) [Streptococcus pyogenes strain TSPY270]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNHISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHD
LTVIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
RNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide


Download         Length: 2340 bp        

>NTDB_id=416580 H7786_RS07630 WP_030126291.1 1530213..1532552(-) (mutS/mutS2) [Streptococcus pyogenes strain TSPY270]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
ACAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAGAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCATATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACGCATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATTTCTAATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTGTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGTAATTGTCATCACTGGCCCTAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CGCAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCTATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGTCCTACGTATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAAGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAATCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGCCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCACCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTAGCCTCGTTAGAGTCCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCAATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGGATTGGTACAGGCGTTATTCGTGAGGG
AGTGACAAAATATCTTCGTCGTCATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGTGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(704-778)

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-669)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.633

100

0.412