Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   H7796_RS00660 Genome accession   NZ_CP060640
Coordinates   104644..104928 (+) Length   94 a.a.
NCBI ID   WP_307777288.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY764     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 99644..109928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7796_RS00635 (H7796_00645) - 101590..101955 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7796_RS00640 (H7796_00650) comGA 102048..102986 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  H7796_RS00645 (H7796_00655) comGB 102922..103956 (+) 1035 WP_228631569.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7796_RS00650 (H7796_00660) comGC 103958..104284 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  H7796_RS00655 (H7796_00665) comGD 104259..104687 (+) 429 WP_076639399.1 competence type IV pilus minor pilin ComGD Machinery gene
  H7796_RS00660 (H7796_00670) comGE 104644..104928 (+) 285 WP_307777288.1 competence type IV pilus minor pilin ComGE Machinery gene
  H7796_RS00665 (H7796_00675) comGF 104921..105355 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7796_RS00670 (H7796_00680) comGG 105339..105665 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  H7796_RS00675 (H7796_00685) comGH 105763..106716 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  H7796_RS00680 (H7796_00690) - 106775..107971 (+) 1197 WP_020904834.1 acetate kinase -
  H7796_RS00685 (H7796_00695) - 108158..108466 (+) 309 Protein_89 hypothetical protein -
  H7796_RS00690 (H7796_00700) proC 108549..109319 (-) 771 WP_076639397.1 pyrroline-5-carboxylate reductase -

Sequence


Protein


Download         Length: 94 a.a.        Molecular weight: 10700.68 Da        Isoelectric Point: 8.9043

>NTDB_id=415660 H7796_RS00660 WP_307777288.1 104644..104928(+) (comGE) [Streptococcus pyogenes strain TSPY764]
MGIIKKQVKAYIVLESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=415660 H7796_RS00660 WP_307777288.1 104644..104928(+) (comGE) [Streptococcus pyogenes strain TSPY764]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGTCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAT
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383


Multiple sequence alignment