Detailed information NTG0041371

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: HMPREF0833_RS01140
• Genome accession: NC_015678
• Coordinates: 228007..228846 (+)
• Length: 279 a.a.
• NCBI ID: WP_013903325.1
• Uniprot ID: F8DFP0
• Organism: Streptococcus parasanguinis ATCC 15912
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 223007..233846

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0833_RS01110 (HMPREF0833_10213)	-	223261..224142 (+)	882	WP_013903320.1	F0F1 ATP synthase subunit gamma	-
HMPREF0833_RS01115 (HMPREF0833_10214)	atpD	224228..225634 (+)	1407	WP_013903321.1	F0F1 ATP synthase subunit beta	-
HMPREF0833_RS01120 (HMPREF0833_10215)	-	225648..226067 (+)	420	WP_003002471.1	F0F1 ATP synthase subunit epsilon	-
HMPREF0833_RS01125 (HMPREF0833_10216)	-	226166..226396 (+)	231	WP_013903322.1	DUF1146 family protein	-
HMPREF0833_RS01130 (HMPREF0833_10217)	murA	226463..227746 (+)	1284	WP_013903323.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
HMPREF0833_RS01135 (HMPREF0833_10218)	-	227736..227924 (+)	189	WP_013903324.1	DNA-directed RNA polymerase subunit beta	-
HMPREF0833_RS01140 (HMPREF0833_10219)	endA	228007..228846 (+)	840	WP_013903325.1	DNA/RNA non-specific endonuclease	Machinery gene
HMPREF0833_RS01145 (HMPREF0833_10220)	-	228928..229647 (+)	720	WP_013903326.1	M57 family metalloprotease	-
HMPREF0833_RS01150 (HMPREF0833_10221)	-	229754..231661 (+)	1908	WP_013903327.1	ABC-F family ATP-binding cassette domain-containing protein	-
HMPREF0833_RS01155 (HMPREF0833_10222)	-	231870..232226 (+)	357	WP_013903328.1	hypothetical protein	-
HMPREF0833_RS01160 (HMPREF0833_10223)	-	232231..233103 (+)	873	WP_013903329.1	XRE/MutR family transcriptional regulator	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 30505.98 Da
• Isoelectric Point: 9.2839

>NTDB_id=41371 HMPREF0833_RS01140 WP_013903325.1 228007..228846(+) (endA) [Streptococcus parasanguinis ATCC 15912]
MTKQIVSKRTKQTLAGFVVATALAIGGYYFNQSSVKEATDQVVSVVTSSQEETPSKELASSVLTKSAFSQLGNDLEWNGV
GAFVVKGNRTDLDASVASQPYADNKTKEVNGKTVPTVANAIMTKATRQYRDRDATGSGRTDWKPAGWHQVHNLSGEYDHA
VDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWSNQANDPHSTGQNYYETLVRKALDKNKRIRYRVTLIYNQPEDLIPL
GSQIEAKSSDGTLEFNVFVPNVQSGMSLDYQTGKVTIHQ

Nucleotide

• Length: 840 bp

>NTDB_id=41371 HMPREF0833_RS01140 WP_013903325.1 228007..228846(+) (endA) [Streptococcus parasanguinis ATCC 15912]
ATGACAAAACAAATAGTAAGCAAACGAACCAAACAAACGCTAGCAGGCTTCGTGGTTGCAACAGCCTTAGCAATTGGTGG
TTATTATTTTAATCAATCGTCGGTAAAAGAAGCGACGGATCAGGTTGTTTCCGTGGTGACTAGTAGCCAAGAGGAAACAC
CCAGTAAAGAGTTAGCTAGCTCTGTACTAACGAAATCTGCTTTTTCACAATTGGGGAATGACTTGGAATGGAACGGAGTT
GGAGCCTTCGTTGTCAAGGGCAATCGAACAGATTTGGATGCCAGTGTGGCTAGTCAACCCTATGCAGATAACAAGACAAA
AGAGGTGAATGGAAAGACCGTACCGACAGTTGCCAATGCCATCATGACTAAGGCGACTCGTCAGTACAGAGATCGCGATG
CAACAGGAAGTGGCCGAACCGATTGGAAACCTGCAGGTTGGCATCAGGTTCATAATCTGTCAGGCGAGTACGACCATGCT
GTGGATAGAGGTCATCTATTGGGCTACGCCTTGATCGGCAATCTCAAAGGCTTTGATGCTTCGACTAGTAATCCCAAAAA
TATCGCCGTCCAAACGGCTTGGTCTAATCAAGCCAATGATCCTCATTCCACCGGTCAAAACTACTATGAGACTCTGGTTC
GAAAAGCGCTGGATAAGAACAAGCGGATCCGCTATCGGGTCACCTTGATCTACAATCAGCCGGAAGATCTGATTCCTTTA
GGTTCTCAGATCGAAGCCAAATCGAGTGATGGGACCCTTGAGTTCAATGTCTTTGTTCCCAATGTTCAAAGTGGAATGAG
CCTGGATTACCAGACAGGAAAAGTAACCATCCATCAATAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (81-251)

3D structure

• AlphaFold DB: F8DFP0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	63.139	98.208	0.62
endA	Streptococcus pneumoniae D39	63.139	98.208	0.62
endA	Streptococcus pneumoniae R6	63.139	98.208	0.62
endA	Streptococcus pneumoniae TIGR4	63.139	98.208	0.62