Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   H6X75_RS02065 Genome accession   NZ_CP060156
Coordinates   390203..392539 (+) Length   778 a.a.
NCBI ID   WP_001035038.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700608     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 385203..397539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H6X75_RS02045 (H6X75_02020) lepB 387666..388280 (-) 615 WP_001820908.1 signal peptidase I -
  H6X75_RS02050 (H6X75_02025) rnhC 388284..389165 (-) 882 WP_000146853.1 ribonuclease HIII -
  H6X75_RS02055 (H6X75_02030) zapA 389252..389554 (+) 303 WP_000002019.1 cell division protein ZapA -
  H6X75_RS02060 (H6X75_02035) - 389551..390099 (+) 549 WP_000622953.1 CvpA family protein -
  H6X75_RS02065 (H6X75_02040) mutS/mutS2 390203..392539 (+) 2337 WP_001035038.1 endonuclease MutS2 Machinery gene
  H6X75_RS02070 (H6X75_02045) - 392589..393518 (-) 930 WP_001150388.1 helix-turn-helix transcriptional regulator -
  H6X75_RS02075 (H6X75_02050) - 393727..394254 (+) 528 WP_000598974.1 hypothetical protein -
  H6X75_RS02080 (H6X75_02055) - 394264..395802 (+) 1539 WP_000030105.1 Hsp70 family protein -
  H6X75_RS02085 (H6X75_02060) - 395815..397182 (+) 1368 WP_000111448.1 hypothetical protein -

Sequence

Protein


Download         Length: 778 a.a.        Molecular weight: 87504.50 Da        Isoelectric Point: 7.0147

>NTDB_id=413487 H6X75_RS02065 WP_001035038.1 390203..392539(+) (mutS/mutS2) [Streptococcus pneumoniae strain PZ900700608]
MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLGPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEM
GAALNIEEFLLLKRVLLASRELQSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
SESRVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADER
YEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQD
LTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVN
QHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPG
RSNAFEIAKRLGLSEVIVGDASQQVDQDNDVNRIIEQLEEQTLESHKRLDNIREVEQENLKMNRALKKLYNELNREKETE
LNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKILQKAKKKRAPKVGDDIVVLSY
GQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQVQQEKPVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDAFI
DQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG

Nucleotide


Download         Length: 2337 bp        

>NTDB_id=413487 H6X75_RS02065 WP_001035038.1 390203..392539(+) (mutS/mutS2) [Streptococcus pneumoniae strain PZ900700608]
ATGAATAAGAAAATATTAGAAACATTAGAGTTCGATAAGGTCAAGGCCTTGTTTGAGCCTCATTTGTTGACCGAGCAGGG
CTTGGAGCAATTGAGACAGCTGGGTCCGACTGCCAAAGCAGATAAAATCAAACAGGCTTTTGCTGAGATGAAGGAAATGC
AGGCTCTTTTCGTCGAGCAACCGCATTTTACTATTCTCTCAACTAAGGAAATTGCAGGAGTCTGCAAGAGGTTGGAGATG
GGAGCGGCTCTCAATATCGAGGAGTTCCTACTCTTGAAACGCGTGCTTCTTGCCAGCCGAGAACTTCAAAGTTTTTACGC
CAATCTGGAAAATGTCAGCTTGGAAGAATTAGCCCTTTGGTTTGAGAAATTACATGATTTTCCGCAATTACAAGGAAATC
TTCAGGCCTTTAATGATGCGGGTTTCATTGAAAATTTTGCCAGTGAAGAATTGGCGCGAATCCGTCGAAAAATACATGAT
AGCGAGAGTCGGGTACGCGATGTTTTACAAGACTTGCTCAAGCAAAAAGCGCAGATGTTGACAGAAGGAATTGTTGCTAG
CAGAAATGGCCGTCAGGTTTTACCAGTCAAAAACACCTACCGCAATAAGATTGCAGGTGTCGTTCATGATATTTCTGCTA
GTGGAAACACCGTCTATATCGAACCACGTGAGGTAGTCAAACTGAGCGAAGAAATTGCTAGTCTGCGAGCAGATGAGCGC
TATGAAATGCTTCGCATTCTCCAAGAAATTTCTGAGCGTGTCCGCCCTCATGCGGCTGAGATTGCCAATGACGCCTGGAT
TATCGGTCATCTAGACTTGATTCGTGCCAAGGTCCGCTTTATCCAAGAAAGGCAAGCAGTCGTACCTCAGCTGTCAGAAA
ATCAAGAGATTCAACTGCTCCATGTCTGCCATCCTTTGGTCAAAAATGCTGTCGCAAATGATGTCCATTTTGGTCAAGAT
TTAACAGCTATTGTCATTACAGGTCCCAATACAGGTGGTAAGACCATCATGCTTAAAACTCTCGGCTTGACACAGGTCAT
GGCTCAGTCCGGTTTGCCGATTTTAGCAGATAAGGGAAGTCGTGTTGGTATCTTTGAAGAAATCTTTGCCGATATTGGAG
ATGAGCAGTCTATTGAGCAGAGCTTGTCTACCTTCTCTAGCCACATGACCAATATCGTGGATATTCTTGGCAAGGTCAAT
CAACATTCACTCTTACTCTTGGATGAGTTGGGGGCTGGTACAGACCCTCAAGAAGGAGCTGCTCTTGCCATGGCTATTCT
GGAGGACCTTCGCCTGCGTCAAATCAAGACTATGGCGACTACCCACTATCCGGAACTAAAGGCTTACGGTATTGAGACAG
CCTTTGTGCAAAATGCTAGTATGGAGTTTGATACTGCAACTCTTCGCCCGACTTATCGCTTTATGCAGGGTGTTCCTGGC
CGAAGTAATGCCTTTGAAATTGCCAAACGTCTAGGCCTATCTGAAGTTATCGTAGGGGATGCCAGCCAGCAGGTCGATCA
GGACAATGATGTCAATCGGATTATTGAACAATTGGAAGAGCAGACGCTTGAAAGTCATAAACGCTTGGACAATATCCGTG
AGGTGGAGCAAGAAAATCTCAAGATGAACCGTGCTCTCAAAAAACTTTACAACGAACTCAATCGTGAAAAGGAAACCGAG
CTTAATAAGGCGCGTGAACAGGCTGCTGAGATTGTGGACATGGCCCTCAGTGAGAGTGACCAGATTCTCAAAAATCTCCA
CAGTAAATCTCAACTCAAGCCCCACGAAATCATTGAAGCCAAGGCCAAGCTGAAAAAATTGGCTCCTGAAAAAGTAGATT
TGTCTAAAAACAAGATCCTTCAAAAGGCCAAGAAAAAACGAGCTCCAAAGGTGGGAGATGATATCGTGGTTCTCAGTTAT
GGCCAGCGTGGTACCCTGACCAGTCAACTCAAGGACGGCCGCTGGGAAGCCCAAGTTGGCTTGATTAAGATGACCCTGGA
AGAGAAAGAGTTTGACCTTGTTCAAGTTCAGCAAGAAAAGCCAGTTAAGAAGAAACAAGTCAATGTTGTTAAACGGACAT
CTGGCCGAGGTCCACAAGCCAGACTGGACCTTCGAGGCAAACGCTATGAAGAGGCCATGAATGAGCTAGATGCCTTTATC
GACCAAGCCCTGCTTAACAATATGGCTCAAGTTGATATCATTCATGGTATCGGAACAGGTGTCATCCGTGAAGGAGTCAC
CAAATACCTACAAAGAAACAAACATGTCAAGAGTTTTGGCTATGCCCCACAAAATGCTGGAGGCAGTGGCGCGACTATTG
TCACTTTTAAAGGATAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-506)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)

Smr domain (Smr)

(702-777)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.834

100

0.415