Detailed information
Bioinformatically predicted
Overview
| Name | codY | Type | Regulator |
| Locus tag | FOC12_RS23275 | Genome accession | NZ_CP047111 |
| Coordinates | 4456455..4457234 (+) | Length | 259 a.a. |
| NCBI ID | WP_000421288.1 | Uniprot ID | Q81WK7 |
| Organism | Bacillus anthracis strain FDAARGOS_704 | ||
| Function | repression of comK (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 4417633..4491556 | 4456455..4457234 | within | 0 |
Gene organization within MGE regions
Location: 4417633..4491556
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FOC12_RS23085 (FOC12_23095) | rsmB | 4417791..4419125 (+) | 1335 | WP_001249680.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| FOC12_RS23090 (FOC12_23100) | rlmN | 4419130..4420218 (+) | 1089 | WP_000450543.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| FOC12_RS23095 (FOC12_23105) | - | 4420223..4420975 (+) | 753 | WP_000648699.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| FOC12_RS23100 (FOC12_23110) | prkC | 4420984..4422957 (+) | 1974 | WP_000904759.1 | serine/threonine protein kinase PrkC | - |
| FOC12_RS23105 (FOC12_23115) | rsgA | 4423226..4424107 (+) | 882 | WP_001113935.1 | ribosome small subunit-dependent GTPase A | - |
| FOC12_RS23110 (FOC12_23120) | rpe | 4424110..4424754 (+) | 645 | WP_000589966.1 | ribulose-phosphate 3-epimerase | - |
| FOC12_RS23115 (FOC12_23125) | - | 4424854..4425534 (+) | 681 | WP_025388434.1 | thiamine diphosphokinase | - |
| FOC12_RS23120 (FOC12_23130) | spoVM | 4425601..4425681 (+) | 81 | WP_001213599.1 | stage V sporulation protein SpoVM | - |
| FOC12_RS23125 (FOC12_23135) | rpmB | 4425754..4425942 (-) | 189 | WP_000124778.1 | 50S ribosomal protein L28 | - |
| FOC12_RS23130 (FOC12_23140) | - | 4426321..4426683 (+) | 363 | WP_000021109.1 | Asp23/Gls24 family envelope stress response protein | - |
| FOC12_RS23135 (FOC12_23145) | - | 4426706..4428382 (+) | 1677 | WP_000027136.1 | DAK2 domain-containing protein | - |
| FOC12_RS23140 (FOC12_23150) | recG | 4428672..4430720 (+) | 2049 | WP_001006884.1 | ATP-dependent DNA helicase RecG | - |
| FOC12_RS23145 (FOC12_23155) | fapR | 4430809..4431402 (+) | 594 | WP_000747352.1 | transcription factor FapR | - |
| FOC12_RS23150 (FOC12_23160) | plsX | 4431399..4432391 (+) | 993 | WP_000684111.1 | phosphate acyltransferase PlsX | - |
| FOC12_RS23155 (FOC12_23165) | fabD | 4432406..4433350 (+) | 945 | WP_000516958.1 | ACP S-malonyltransferase | - |
| FOC12_RS23160 (FOC12_23170) | fabG | 4433350..4434090 (+) | 741 | WP_000911782.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| FOC12_RS23165 (FOC12_23175) | acpP | 4434160..4434393 (+) | 234 | WP_000786062.1 | acyl carrier protein | - |
| FOC12_RS23170 (FOC12_23180) | rncS | 4434452..4435189 (+) | 738 | WP_001146873.1 | ribonuclease III | - |
| FOC12_RS23175 (FOC12_23185) | smc | 4435336..4438905 (+) | 3570 | WP_000478985.1 | chromosome segregation protein SMC | - |
| FOC12_RS23180 (FOC12_23190) | ftsY | 4438921..4439910 (+) | 990 | WP_000007650.1 | signal recognition particle-docking protein FtsY | - |
| FOC12_RS23185 (FOC12_23195) | - | 4440043..4440375 (+) | 333 | WP_000891062.1 | putative DNA-binding protein | - |
| FOC12_RS23190 (FOC12_23200) | ffh | 4440388..4441737 (+) | 1350 | WP_000863456.1 | signal recognition particle protein | - |
| FOC12_RS23195 (FOC12_23205) | rpsP | 4441838..4442110 (+) | 273 | WP_000268750.1 | 30S ribosomal protein S16 | - |
| FOC12_RS23200 (FOC12_23210) | - | 4442125..4442352 (+) | 228 | WP_000737398.1 | KH domain-containing protein | - |
| FOC12_RS23205 (FOC12_23215) | rimM | 4442473..4442988 (+) | 516 | WP_000170269.1 | ribosome maturation factor RimM | - |
| FOC12_RS23210 (FOC12_23220) | trmD | 4442988..4443722 (+) | 735 | WP_000686892.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| FOC12_RS23215 (FOC12_23225) | rplS | 4443869..4444213 (+) | 345 | WP_001186516.1 | 50S ribosomal protein L19 | - |
| FOC12_RS23220 (FOC12_23230) | lepB | 4444315..4444866 (+) | 552 | WP_000711857.1 | signal peptidase I | - |
| FOC12_RS23225 (FOC12_23235) | ylqF | 4444887..4445777 (+) | 891 | WP_000236707.1 | ribosome biogenesis GTPase YlqF | - |
| FOC12_RS23230 (FOC12_23240) | rnhB | 4445829..4446602 (+) | 774 | WP_001174712.1 | ribonuclease HII | - |
| FOC12_RS23235 (FOC12_23245) | sucC | 4446796..4447956 (+) | 1161 | WP_001020786.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| FOC12_RS23240 (FOC12_23250) | sucD | 4447977..4448879 (+) | 903 | WP_000115178.1 | succinate--CoA ligase subunit alpha | - |
| FOC12_RS23245 (FOC12_23255) | dprA | 4449201..4449835 (+) | 635 | Protein_4589 | DNA-processing protein DprA | - |
| FOC12_RS23250 (FOC12_23260) | topA | 4449980..4452058 (+) | 2079 | WP_001286969.1 | type I DNA topoisomerase | - |
| FOC12_RS23255 (FOC12_23265) | trmFO | 4452109..4453413 (+) | 1305 | WP_003161605.1 | FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO | - |
| FOC12_RS23260 (FOC12_23270) | xerC | 4453479..4454378 (+) | 900 | WP_001101226.1 | tyrosine recombinase XerC | - |
| FOC12_RS23265 (FOC12_23275) | hslV | 4454421..4454963 (+) | 543 | WP_000526272.1 | ATP-dependent protease proteolytic subunit HslV | - |
| FOC12_RS23270 (FOC12_23280) | hslU | 4454986..4456377 (+) | 1392 | WP_000550088.1 | ATP-dependent protease ATPase subunit HslU | - |
| FOC12_RS23275 (FOC12_23285) | codY | 4456455..4457234 (+) | 780 | WP_000421288.1 | GTP-sensing pleiotropic transcriptional regulator CodY | Regulator |
| FOC12_RS23280 (FOC12_23290) | rpsB | 4457584..4458285 (+) | 702 | WP_000111483.1 | 30S ribosomal protein S2 | - |
| FOC12_RS23285 (FOC12_23295) | tsf | 4458389..4459276 (+) | 888 | WP_001018581.1 | translation elongation factor Ts | - |
| FOC12_RS23290 (FOC12_23300) | pyrH | 4459343..4460065 (+) | 723 | WP_000042663.1 | UMP kinase | - |
| FOC12_RS23295 (FOC12_23305) | frr | 4460068..4460625 (+) | 558 | WP_000531498.1 | ribosome recycling factor | - |
| FOC12_RS23300 (FOC12_23310) | uppS | 4460711..4461487 (+) | 777 | WP_000971303.1 | isoprenyl transferase | - |
| FOC12_RS23305 (FOC12_23315) | cdsA | 4461505..4462296 (+) | 792 | WP_000813581.1 | phosphatidate cytidylyltransferase | - |
| FOC12_RS23310 (FOC12_23320) | dxr | 4462320..4463462 (+) | 1143 | WP_000790359.1 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase | - |
| FOC12_RS23315 (FOC12_23325) | rseP | 4463479..4464735 (+) | 1257 | WP_001090228.1 | RIP metalloprotease RseP | - |
| FOC12_RS23320 (FOC12_23330) | - | 4464845..4466545 (+) | 1701 | WP_000814312.1 | proline--tRNA ligase | - |
| FOC12_RS23325 (FOC12_23335) | - | 4466670..4470971 (+) | 4302 | WP_000059985.1 | PolC-type DNA polymerase III | - |
| FOC12_RS23330 (FOC12_23340) | rimP | 4471304..4471774 (+) | 471 | WP_000359097.1 | ribosome maturation factor RimP | - |
| FOC12_RS23335 (FOC12_23345) | nusA | 4471792..4472898 (+) | 1107 | WP_000102609.1 | transcription termination factor NusA | - |
| FOC12_RS23340 (FOC12_23350) | rnpM | 4472910..4473182 (+) | 273 | WP_000071128.1 | RNase P modulator RnpM | - |
| FOC12_RS23345 (FOC12_23355) | - | 4473183..4473494 (+) | 312 | WP_001286523.1 | YlxQ family RNA-binding protein | - |
| FOC12_RS23350 (FOC12_23360) | infB | 4473499..4475559 (+) | 2061 | WP_000036339.1 | translation initiation factor IF-2 | - |
| FOC12_RS23355 (FOC12_23365) | - | 4475556..4475837 (+) | 282 | WP_000582364.1 | DUF503 domain-containing protein | - |
| FOC12_RS23360 (FOC12_23370) | rbfA | 4475853..4476209 (+) | 357 | WP_000776446.1 | 30S ribosome-binding factor RbfA | - |
| FOC12_RS23365 (FOC12_23375) | truB | 4476296..4477219 (+) | 924 | WP_000399357.1 | tRNA pseudouridine(55) synthase TruB | - |
| FOC12_RS23370 (FOC12_23380) | ribF | 4477263..4478234 (+) | 972 | WP_000766711.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| FOC12_RS23375 (FOC12_23385) | rpsO | 4478335..4478604 (+) | 270 | WP_001229392.1 | 30S ribosomal protein S15 | - |
| FOC12_RS23380 (FOC12_23390) | pnp | 4478765..4480903 (+) | 2139 | WP_000076733.1 | polyribonucleotide nucleotidyltransferase | - |
| FOC12_RS23385 (FOC12_23395) | - | 4481055..4481954 (+) | 900 | WP_000647529.1 | polysaccharide deacetylase family protein | - |
| FOC12_RS23390 (FOC12_23400) | - | 4482041..4483282 (+) | 1242 | WP_000592993.1 | pitrilysin family protein | - |
| FOC12_RS23395 (FOC12_23405) | - | 4483409..4483660 (+) | 252 | WP_001239752.1 | YlmC/YmxH family sporulation protein | - |
| FOC12_RS23400 (FOC12_23410) | dpaA | 4483935..4484837 (+) | 903 | WP_000954726.1 | dipicolinic acid synthetase subunit A | - |
| FOC12_RS23405 (FOC12_23415) | dpaB | 4484834..4485433 (+) | 600 | WP_001049484.1 | dipicolinate synthase subunit B | - |
| FOC12_RS23410 (FOC12_23420) | asd | 4485584..4486630 (+) | 1047 | WP_000414849.1 | aspartate-semialdehyde dehydrogenase | - |
| FOC12_RS23415 (FOC12_23425) | dapG | 4486654..4487886 (+) | 1233 | WP_000692470.1 | aspartate kinase | - |
| FOC12_RS23420 (FOC12_23430) | dapA | 4487898..4488776 (+) | 879 | WP_000564761.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| FOC12_RS23425 (FOC12_23435) | - | 4489542..4491212 (+) | 1671 | WP_000823085.1 | ribonuclease J | - |
Sequence
Protein
Download Length: 259 a.a. Molecular weight: 28774.05 Da Isoelectric Point: 4.7947
>NTDB_id=410582 FOC12_RS23275 WP_000421288.1 4456455..4457234(+) (codY) [Bacillus anthracis strain FDAARGOS_704]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN
Nucleotide
Download Length: 780 bp
>NTDB_id=410582 FOC12_RS23275 WP_000421288.1 4456455..4457234(+) (codY) [Bacillus anthracis strain FDAARGOS_704]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| codY | Bacillus subtilis subsp. subtilis str. 168 |
81.081 |
100 |
0.811 |
| codY | Lactococcus lactis subsp. lactis strain DGCC12653 |
46.667 |
98.456 |
0.459 |