Detailed information NTG0410187

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1A19_RS04090
• Genome accession: NZ_CP059383
• Coordinates: 739084..739869 (+)
• Length: 261 a.a.
• NCBI ID: WP_000825431.1
• Uniprot ID: Q8E0P2
• Organism: Streptococcus agalactiae strain BJ01
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 734084..744869

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1A19_RS04060 (H1A19_04060)	-	735201..735644 (+)	444	WP_001048166.1	hypothetical protein	-
H1A19_RS04065 (H1A19_04065)	-	735729..735995 (+)	267	WP_001865676.1	hypothetical protein	-
H1A19_RS04070 (H1A19_04070)	-	736096..736224 (+)	129	WP_000962057.1	hypothetical protein	-
H1A19_RS04075 (H1A19_04075)	-	736233..736553 (+)	321	WP_001865677.1	hypothetical protein	-
H1A19_RS04080 (H1A19_04080)	-	736650..737321 (+)	672	WP_000891268.1	ATP-binding cassette domain-containing protein	-
H1A19_RS04085 (H1A19_04085)	-	737378..738823 (-)	1446	WP_000750933.1	FAD/NAD(P)-binding protein	-
H1A19_RS04090 (H1A19_04090)	endA	739084..739869 (+)	786	WP_000825431.1	DNA/RNA non-specific endonuclease	Machinery gene
H1A19_RS04095 (H1A19_04095)	-	739947..740585 (-)	639	WP_000478529.1	VTT domain-containing protein	-
H1A19_RS04100 (H1A19_04100)	-	740802..741458 (+)	657	WP_000121094.1	ATP-binding cassette domain-containing protein	-
H1A19_RS04105 (H1A19_04105)	fetB	741455..742228 (+)	774	WP_000012390.1	iron export ABC transporter permease subunit FetB	-
H1A19_RS04110 (H1A19_04110)	-	742392..743210 (+)	819	WP_000601007.1	hypothetical protein	-
H1A19_RS04115 (H1A19_04115)	-	743247..744131 (-)	885	WP_000354840.1	LysR family transcriptional regulator	-
H1A19_RS04120 (H1A19_04120)	-	744324..744830 (+)	507	Protein_738	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29424.86 Da
• Isoelectric Point: 8.9989

>NTDB_id=410187 H1A19_RS04090 WP_000825431.1 739084..739869(+) (endA) [Streptococcus agalactiae strain BJ01]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide

• Length: 786 bp

>NTDB_id=410187 H1A19_RS04090 WP_000825431.1 739084..739869(+) (endA) [Streptococcus agalactiae strain BJ01]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (77-235)

3D structure

• AlphaFold DB: Q8E0P2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	51.515	75.862	0.391
endA	Streptococcus pneumoniae D39	51.515	75.862	0.391
endA	Streptococcus pneumoniae R6	51.515	75.862	0.391
endA	Streptococcus pneumoniae TIGR4	51.515	75.862	0.391