Detailed information NTG0409208

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: SAURSH1000_RS05745
• Genome accession: NZ_CP059180
• Coordinates: 1188277..1189050 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain SH1000
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1183277..1194050

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAURSH1000_RS05725 (SAURSH1000_001143)	trmFO	1183621..1184928 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
SAURSH1000_RS05730 (SAURSH1000_001144)	xerC	1185345..1186241 (+)	897	WP_001015597.1	tyrosine recombinase XerC	-
SAURSH1000_RS05735 (SAURSH1000_001145)	hslV	1186238..1186783 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
SAURSH1000_RS05740 (SAURSH1000_001146)	hslU	1186849..1188252 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
SAURSH1000_RS05745 (SAURSH1000_001147)	codY	1188277..1189050 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
SAURSH1000_RS05750 (SAURSH1000_001148)	-	1189101..1189193 (+)	93	WP_001790530.1	hypothetical protein	-
SAURSH1000_RS05755 (SAURSH1000_001149)	rpsB	1189392..1190159 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
SAURSH1000_RS05760 (SAURSH1000_001150)	-	1190193..1190306 (+)	114	WP_001789890.1	hypothetical protein	-
SAURSH1000_RS05765 (SAURSH1000_001151)	tsf	1190341..1191222 (+)	882	WP_000201387.1	translation elongation factor Ts	-
SAURSH1000_RS05770 (SAURSH1000_001152)	pyrH	1191359..1192081 (+)	723	WP_000057330.1	UMP kinase	-
SAURSH1000_RS05775 (SAURSH1000_001153)	frr	1192100..1192654 (+)	555	WP_001280006.1	ribosome recycling factor	-
SAURSH1000_RS05780 (SAURSH1000_001154)	-	1193027..1193797 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=409208 SAURSH1000_RS05745 WP_000055337.1 1188277..1189050(+) (codY) [Staphylococcus aureus strain SH1000]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=409208 SAURSH1000_RS05745 WP_000055337.1 1188277..1189050(+) (codY) [Staphylococcus aureus strain SH1000]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428