Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   GPY21_RS19395 Genome accession   NZ_CP046754
Coordinates   2151833..2154091 (-) Length   752 a.a.
NCBI ID   WP_005495920.1    Uniprot ID   A0A249W7Z7
Organism   Vibrio parahaemolyticus strain 2015AW-0174     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2146833..2159091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPY21_RS19375 kdsB 2148125..2148880 (-) 756 WP_005495914.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  GPY21_RS19380 - 2148880..2149059 (-) 180 WP_005378451.1 Trm112 family protein -
  GPY21_RS19385 lpxK 2149040..2150047 (-) 1008 WP_005495917.1 tetraacyldisaccharide 4'-kinase -
  GPY21_RS19390 msbA 2150053..2151801 (-) 1749 WP_005495919.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  GPY21_RS19395 comEC 2151833..2154091 (-) 2259 WP_005495920.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GPY21_RS19400 - 2154100..2154609 (+) 510 WP_005456245.1 DUF2062 domain-containing protein -
  GPY21_RS19405 lolE 2154814..2156058 (-) 1245 WP_005495922.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  GPY21_RS19410 lolD 2156061..2156768 (-) 708 WP_005495923.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  GPY21_RS19415 lolC 2156761..2157969 (-) 1209 WP_029815716.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  GPY21_RS19420 - 2158234..2158803 (+) 570 WP_005495925.1 PilZ domain-containing protein -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 84677.16 Da        Isoelectric Point: 9.5001

>NTDB_id=407196 GPY21_RS19395 WP_005495920.1 2151833..2154091(-) (comEC) [Vibrio parahaemolyticus strain 2015AW-0174]
MTLLEKSWTLALFVASVISSAWWPTMPDWRWLLLGIITTGSIIKLRRGLISIGVIVGFMVVIVHGNIMEYQRQALFQAGE
NSTIIGRVDSSFTQISHGYEGVVAIKQVNSHTLLPFLKPKVRLITPFPLAVNSEFTTNVLIKPIIGLRNEAGFDAEKQSM
GSGVVARAVVTKDSYWVIRTSSSWREAIIQTVERDISRLEHFALIKALAFADRTGLTKEDWQSLRDSGLLHLVSISGLHI
GMALTFGLALGGLIRLAMPRYWFLPSVSGLAFAIVYAWLADFSLPTTRAVSVCIIYLALKYWLVHWSPWRVLLLAVALQL
FFQPFASFSLSFWLSYLSVGAVLFAVNTVQDSKEGRLGKLRILLLTQLILSLLIVPISGYFFSGFSWSSLVYNLVFIPWF
GFVVVPIMFAALIASLLFPMLATVLWYLLDIFLVPLSWSVRYAIGTWQPISAEWTFVIAVVSAVLVLRHVMPRYVWMFVC
VIVVMTGLFPKQDNQTWRIDVLDVGHGLAVLVEKEGRVLLYDTGKAWQNGSIAEQVITPVLHRRGYSSVDTMILSHADND
HAGGRKVIEQYFSPKHKLSSQSFLHYQPCIAAEKWKWQGLNMEVLWPPKPVVRAYNPHSCVISLEDPSSGFKMLFTGDIE
AISEWILLREPEKLRSDVMLVPHHGSKTSSNPKFINVVEPSLAIASTAKLNQWGMPAPEVVQAYTDSGVSWLDTGSDGQI
TILLDGNNWRFESKRRETIEPWYRQMLRNRVE

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=407196 GPY21_RS19395 WP_005495920.1 2151833..2154091(-) (comEC) [Vibrio parahaemolyticus strain 2015AW-0174]
ATGACTCTCTTAGAAAAAAGTTGGACCTTGGCGTTATTTGTCGCGAGCGTAATTTCGTCTGCATGGTGGCCGACGATGCC
AGATTGGCGTTGGTTGCTGCTGGGAATAATTACCACTGGCTCAATAATTAAATTACGTCGAGGCTTAATTAGCATAGGCG
TAATTGTGGGCTTTATGGTTGTCATCGTCCACGGCAATATTATGGAGTATCAGAGACAAGCCCTTTTTCAAGCAGGTGAG
AATAGTACCATAATTGGTAGAGTTGACAGCTCTTTTACGCAAATAAGTCACGGATATGAAGGTGTCGTAGCGATAAAACA
AGTGAATTCTCACACTCTGTTACCTTTTCTTAAACCTAAAGTCCGCCTTATAACGCCATTCCCACTAGCTGTTAACAGTG
AGTTTACGACTAACGTTTTGATTAAGCCCATTATCGGCCTCAGAAATGAAGCGGGTTTCGACGCAGAAAAGCAGTCAATG
GGAAGTGGTGTTGTTGCAAGGGCGGTCGTAACTAAAGATTCATACTGGGTCATTCGTACTTCTTCGTCTTGGCGCGAAGC
TATTATTCAAACTGTTGAGCGTGATATTTCTCGCCTTGAGCATTTTGCTCTAATCAAAGCACTGGCTTTTGCTGATCGCA
CTGGGCTTACCAAAGAGGATTGGCAGTCTCTGCGTGACAGCGGACTACTGCATCTTGTATCGATTTCTGGTTTACACATT
GGGATGGCACTGACGTTTGGGCTCGCCCTTGGTGGGCTTATTCGGCTTGCTATGCCGCGATATTGGTTTCTGCCATCAGT
GAGTGGGTTGGCGTTTGCCATTGTTTACGCTTGGCTTGCTGATTTTTCTTTGCCGACGACCCGAGCCGTTTCTGTTTGTA
TCATCTATCTTGCTTTGAAGTATTGGCTTGTTCATTGGAGTCCATGGCGCGTACTGTTATTGGCTGTGGCGTTGCAACTT
TTCTTCCAACCTTTTGCTTCTTTTAGTTTGAGTTTTTGGCTGTCTTATTTATCCGTTGGTGCCGTTTTGTTTGCGGTTAA
CACAGTGCAAGACTCGAAGGAAGGTCGTTTGGGAAAGTTGCGGATACTTCTGTTGACTCAACTGATACTGAGCTTATTGA
TTGTCCCGATCAGTGGCTATTTTTTCTCTGGATTTAGCTGGTCTTCTTTAGTCTACAATTTGGTTTTCATTCCTTGGTTT
GGCTTTGTTGTCGTTCCAATCATGTTTGCTGCTTTAATTGCGTCATTGCTCTTTCCTATGTTGGCGACGGTTCTATGGTA
TTTGCTTGACATATTCCTAGTGCCACTAAGTTGGTCGGTTCGATATGCCATAGGAACTTGGCAACCCATTAGTGCCGAGT
GGACATTTGTTATTGCTGTAGTGAGTGCCGTGCTCGTTTTAAGACATGTTATGCCTCGTTACGTTTGGATGTTTGTCTGT
GTAATTGTTGTGATGACAGGGTTGTTTCCTAAGCAAGATAACCAAACTTGGCGTATTGATGTGCTTGATGTCGGGCATGG
GTTGGCGGTGCTGGTCGAAAAAGAGGGGAGAGTTTTACTCTATGATACGGGCAAGGCTTGGCAAAACGGCAGTATAGCTG
AGCAAGTGATTACGCCAGTACTGCACCGCAGAGGTTACTCAAGTGTCGATACGATGATTTTAAGTCATGCCGATAATGAC
CATGCTGGCGGCCGAAAAGTGATAGAGCAGTACTTTTCACCTAAACACAAACTAAGCAGCCAGAGCTTTTTACATTATCA
GCCTTGTATTGCTGCTGAGAAATGGAAGTGGCAAGGGTTGAACATGGAGGTACTTTGGCCTCCTAAACCTGTTGTACGTG
CATACAACCCCCACTCTTGTGTCATCAGTCTGGAAGACCCTAGTTCAGGTTTTAAAATGTTGTTCACTGGTGATATCGAA
GCCATCAGCGAATGGATCCTGCTTCGAGAGCCAGAAAAGCTGCGCAGTGATGTAATGCTAGTGCCGCATCATGGAAGCAA
AACCTCTTCTAATCCTAAGTTTATCAATGTTGTTGAGCCTAGCTTGGCTATTGCGTCAACGGCAAAACTAAACCAGTGGG
GAATGCCTGCACCTGAAGTCGTTCAGGCCTATACCGATAGTGGTGTTAGTTGGTTAGACACTGGAAGTGATGGCCAAATA
ACAATCTTACTTGATGGCAATAACTGGCGTTTTGAAAGTAAACGTCGTGAGACAATTGAGCCTTGGTATAGGCAGATGCT
GCGTAACCGAGTAGAATAA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(504-678)

Competence protein (Competence)

(208-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A249W7Z7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio parahaemolyticus RIMD 2210633

99.335

100

0.993
  comEC Vibrio campbellii strain DS40M4

67.021

100

0.67
  comEC Vibrio cholerae strain A1552

41.612

100

0.419

Multiple sequence alignment