Detailed information NTG0406370

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: S9968_RS07425
• Genome accession: NZ_CP058666
• Coordinates: 1394398..1395183 (+)
• Length: 261 a.a.
• NCBI ID: WP_000825431.1
• Uniprot ID: Q8E0P2
• Organism: Streptococcus agalactiae strain S9968
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1389398..1400183

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
S9968_RS07395 (S9968_101476)	-	1390515..1390958 (+)	444	WP_001048166.1	hypothetical protein	-
S9968_RS07400 (S9968_101477)	-	1391043..1391309 (+)	267	WP_001865676.1	hypothetical protein	-
S9968_RS07405	-	1391410..1391538 (+)	129	WP_000962057.1	hypothetical protein	-
S9968_RS07410 (S9968_101478)	-	1391547..1391867 (+)	321	WP_001865677.1	hypothetical protein	-
S9968_RS07415 (S9968_101479)	-	1391964..1392635 (+)	672	WP_000891268.1	ATP-binding cassette domain-containing protein	-
S9968_RS07420 (S9968_101480)	-	1392692..1394137 (-)	1446	WP_000750933.1	FAD/NAD(P)-binding protein	-
S9968_RS07425 (S9968_101481)	endA	1394398..1395183 (+)	786	WP_000825431.1	DNA/RNA non-specific endonuclease	Machinery gene
S9968_RS07430 (S9968_101482)	-	1395261..1395899 (-)	639	WP_000478529.1	VTT domain-containing protein	-
S9968_RS07435 (S9968_101483)	-	1396116..1396772 (+)	657	WP_000121094.1	ATP-binding cassette domain-containing protein	-
S9968_RS07440 (S9968_101484)	fetB	1396769..1397542 (+)	774	WP_000012390.1	iron export ABC transporter permease subunit FetB	-
S9968_RS07445 (S9968_101485)	-	1397706..1398524 (+)	819	WP_000601007.1	hypothetical protein	-
S9968_RS07450 (S9968_101486)	-	1398561..1399445 (-)	885	WP_000354840.1	LysR family transcriptional regulator	-
S9968_RS07455 (S9968_101487)	-	1399638..1400144 (+)	507	Protein_1401	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29424.86 Da
• Isoelectric Point: 8.9989

>NTDB_id=406370 S9968_RS07425 WP_000825431.1 1394398..1395183(+) (endA) [Streptococcus agalactiae strain S9968]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide

• Length: 786 bp

>NTDB_id=406370 S9968_RS07425 WP_000825431.1 1394398..1395183(+) (endA) [Streptococcus agalactiae strain S9968]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (77-235)

3D structure

• AlphaFold DB: Q8E0P2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	51.515	75.862	0.391
endA	Streptococcus pneumoniae D39	51.515	75.862	0.391
endA	Streptococcus pneumoniae R6	51.515	75.862	0.391
endA	Streptococcus pneumoniae TIGR4	51.515	75.862	0.391