Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   HZR12_RS08275 Genome accession   NZ_CP058615
Coordinates   1646295..1647068 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain 110900     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1641295..1652068
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HZR12_RS08240 (HZR12_08240) - 1641548..1642318 (-) 771 WP_000473705.1 isoprenyl transferase -
  HZR12_RS08245 (HZR12_08245) frr 1642691..1643245 (-) 555 WP_001280006.1 ribosome recycling factor -
  HZR12_RS08250 (HZR12_08250) pyrH 1643264..1643986 (-) 723 WP_000057330.1 UMP kinase -
  HZR12_RS08255 (HZR12_08255) tsf 1644123..1645004 (-) 882 WP_000201387.1 translation elongation factor Ts -
  HZR12_RS08260 (HZR12_08260) - 1645039..1645152 (-) 114 WP_001789890.1 hypothetical protein -
  HZR12_RS08265 (HZR12_08265) rpsB 1645186..1645953 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  HZR12_RS08270 (HZR12_08270) - 1646152..1646244 (-) 93 WP_001790530.1 hypothetical protein -
  HZR12_RS08275 (HZR12_08275) codY 1646295..1647068 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  HZR12_RS08280 (HZR12_08280) hslU 1647093..1648496 (-) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  HZR12_RS08285 (HZR12_08285) hslV 1648562..1649107 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  HZR12_RS08290 (HZR12_08290) xerC 1649104..1650000 (-) 897 WP_001015597.1 tyrosine recombinase XerC -
  HZR12_RS08295 (HZR12_08295) trmFO 1650417..1651724 (-) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=405950 HZR12_RS08275 WP_000055337.1 1646295..1647068(-) (codY) [Staphylococcus aureus strain 110900]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=405950 HZR12_RS08275 WP_000055337.1 1646295..1647068(-) (codY) [Staphylococcus aureus strain 110900]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment