Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/comEC   Type   Machinery gene
Locus tag   MARKY_RS11300 Genome accession   NC_015387
Coordinates   2263140..2265203 (+) Length   687 a.a.
NCBI ID   WP_013705010.1    Uniprot ID   F2NRB7
Organism   Marinithermus hydrothermalis DSM 14884     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2258140..2270203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MARKY_RS11270 (Marky_2241) - 2259024..2259749 (-) 726 WP_013705005.1 FadR/GntR family transcriptional regulator -
  MARKY_RS11275 (Marky_2242) - 2259905..2260930 (+) 1026 WP_013705006.1 GntG family PLP-dependent aldolase -
  MARKY_RS11515 - 2260934..2261728 (-) 795 WP_052297184.1 hypothetical protein -
  MARKY_RS11285 (Marky_2244) - 2261730..2261924 (-) 195 WP_041658101.1 hypothetical protein -
  MARKY_RS11290 (Marky_2245) - 2262011..2262673 (+) 663 WP_013705008.1 hypothetical protein -
  MARKY_RS12255 - 2262784..2262900 (+) 117 Protein_2216 SLBB domain-containing protein -
  MARKY_RS12260 - 2262967..2263140 (+) 174 Protein_2217 helix-hairpin-helix domain-containing protein -
  MARKY_RS11300 (Marky_2247) comA/comEC 2263140..2265203 (+) 2064 WP_013705010.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  MARKY_RS11305 (Marky_2248) - 2265207..2266025 (-) 819 WP_013705011.1 ParB/RepB/Spo0J family partition protein -
  MARKY_RS11310 (Marky_2249) - 2266009..2266761 (-) 753 WP_013705012.1 ParA family protein -
  MARKY_RS11315 (Marky_2250) - 2266758..2267306 (-) 549 WP_013705013.1 RsmG family class I SAM-dependent methyltransferase -
  MARKY_RS11320 (Marky_2251) mnmG 2267303..2269129 (-) 1827 WP_013705014.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG -

Sequence

Protein


Download         Length: 687 a.a.        Molecular weight: 72817.73 Da        Isoelectric Point: 10.3005

>NTDB_id=40331 MARKY_RS11300 WP_013705010.1 2263140..2265203(+) (comA/comEC) [Marinithermus hydrothermalis DSM 14884]
MPFALAAGSLLAALLQLSPAFVLGAVLAFGIRPLPARWAFLAGFVLVGLRVLTLPDPWAPLVGRTVTLEGTVRDGFLYTE
RGRIRLDVYPPLADGTATLTGTVRRPQSPRNPGGFDEAGWLRGLGVRAVLEVARVEVHQPSPPGVKDRVRAALEAGLSPE
AAALIRALTLGERRALGKDREAFQRAGLAHVLALSGLHVGILTGFLVLALAPLGPGRYLAALLVLWAYLGLVGPTPSLVR
AVLMASAVLLALMLGKGRAPLTGALAFAFAVHVFLEPYAIFSLSFRLSYLAVLGLALTLPRLPPLRGVWGWVGGGVAVTL
AAQALILPLVLHYFHQLPLLSPLTNLVAAPLVTLLVPLGFLKGILGAEVPLLGEVLALPVNLLAGGLLQFVRLAAQAPQL
AWGEISPAGFALYYLALLPPFAVLYGYLRPARAAVLSATAVLAGLLPTLLPRAEVWQLDVGQGDSTLVRLPGGVEVLVDA
GREWAGDDVVRALAALGVDELELAIGTHPDADHVGGLRYVLARVPVGALVLGPPKPGDPLDAALRTEAAAREIPVLTAAR
GATLRVGEATLRFLAPSPAPTGDDNTRSLVFVLEWRGRRVLFTGDAPTETERFWKPERVHVLKVSHHGARTGTGELVLSR
FRPQLALIGVGPNPYGHPHPEVLARLERFGLEVHRTDREGAIRVLLW

Nucleotide


Download         Length: 2064 bp        

>NTDB_id=40331 MARKY_RS11300 WP_013705010.1 2263140..2265203(+) (comA/comEC) [Marinithermus hydrothermalis DSM 14884]
ATGCCTTTCGCACTCGCTGCGGGAAGCCTGCTGGCCGCACTGCTTCAGCTCTCCCCTGCGTTTGTACTCGGCGCGGTTCT
GGCATTTGGGATCCGCCCGCTCCCCGCGCGCTGGGCCTTCCTCGCAGGATTCGTTCTGGTGGGGCTCCGCGTGCTGACGT
TGCCCGATCCCTGGGCTCCCCTAGTAGGGCGGACGGTGACCCTCGAGGGCACGGTTCGGGACGGGTTCTTGTATACGGAA
CGCGGCCGGATCCGGCTCGACGTATACCCGCCGCTTGCGGACGGAACGGCTACCCTGACCGGGACCGTGCGCCGCCCGCA
ATCGCCGCGCAACCCTGGGGGATTTGACGAAGCGGGGTGGCTGCGAGGACTCGGCGTGCGGGCGGTCCTCGAGGTCGCGC
GGGTCGAGGTGCACCAGCCCTCCCCGCCCGGCGTGAAGGACCGGGTGCGCGCGGCGCTAGAGGCCGGCCTGTCCCCGGAA
GCGGCGGCGTTGATCCGAGCCTTGACGCTGGGGGAGCGGCGGGCACTAGGGAAGGACCGGGAGGCGTTCCAGCGCGCCGG
GCTCGCGCACGTTCTGGCGCTTTCCGGTCTGCACGTCGGGATCCTCACGGGCTTCCTGGTGCTGGCCCTGGCGCCGCTGG
GCCCGGGCCGGTACCTCGCAGCCTTGCTCGTGTTGTGGGCGTACCTGGGGCTCGTGGGCCCCACGCCTTCGCTGGTACGC
GCGGTCCTGATGGCCAGCGCCGTGCTGCTCGCCCTCATGCTGGGCAAGGGGCGAGCCCCGCTCACGGGAGCACTCGCCTT
CGCCTTCGCGGTGCACGTCTTCCTCGAGCCTTACGCGATCTTCAGCCTTTCCTTCCGCTTATCGTACCTGGCGGTGCTGG
GCCTTGCCCTGACGCTCCCCCGCCTGCCCCCCCTGCGGGGGGTCTGGGGGTGGGTCGGGGGTGGGGTGGCCGTGACGCTC
GCAGCGCAAGCCTTGATCCTTCCCCTGGTGCTGCACTACTTTCACCAACTGCCCCTCCTCTCCCCTCTGACCAACCTGGT
CGCCGCACCCCTCGTGACGCTGCTGGTGCCCCTGGGGTTTTTGAAGGGAATACTGGGTGCGGAAGTGCCCCTCCTGGGGG
AGGTGCTCGCGCTGCCGGTCAACCTGCTCGCGGGGGGGTTGCTCCAGTTCGTGCGCCTCGCCGCTCAGGCCCCGCAGCTC
GCCTGGGGGGAGATTTCGCCGGCGGGGTTCGCCCTCTACTACCTGGCTCTCCTCCCGCCGTTCGCGGTCCTGTACGGGTA
CCTGCGGCCCGCCCGCGCGGCGGTGCTCTCGGCGACCGCGGTCCTGGCGGGCCTCCTCCCTACCCTCCTGCCCCGCGCCG
AGGTCTGGCAGCTTGACGTCGGCCAGGGGGACTCCACGCTGGTACGGCTGCCGGGGGGCGTGGAAGTCCTGGTGGACGCT
GGGCGGGAGTGGGCTGGGGACGACGTGGTGCGGGCCCTCGCAGCGTTAGGGGTGGACGAGCTGGAGCTGGCGATCGGCAC
CCATCCCGACGCGGACCACGTGGGAGGGCTGCGGTACGTGCTGGCCCGGGTCCCGGTGGGTGCGCTCGTGCTCGGCCCGC
CAAAGCCGGGGGACCCCCTCGACGCCGCCCTTCGTACCGAGGCCGCGGCACGAGAGATTCCGGTACTTACCGCGGCACGT
GGCGCCACGCTGCGCGTGGGGGAGGCGACGCTGCGCTTCCTCGCCCCTTCCCCAGCCCCAACGGGTGACGACAACACGCG
CAGCTTGGTTTTCGTGCTCGAGTGGCGCGGGCGGCGGGTGCTCTTCACCGGGGACGCTCCCACGGAAACGGAGCGGTTCT
GGAAACCGGAGCGGGTGCACGTGCTCAAGGTCAGCCACCACGGGGCCCGCACGGGCACCGGCGAGCTGGTCCTCTCCCGG
TTCCGCCCCCAGCTCGCCCTGATCGGGGTGGGCCCCAACCCGTACGGGCACCCGCACCCCGAGGTGCTGGCGCGCCTCGA
GCGCTTCGGCCTCGAGGTGCACCGCACTGACCGGGAGGGCGCGATTCGGGTCCTGTTGTGGTGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(168-419)

Metallo-beta-lactamase superfamily (Lactamase_B)

(459-644)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2NRB7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/comEC Thermus thermophilus HB27

51.459

94.76

0.488
  comEC Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

39.848

96.07

0.383

Multiple sequence alignment