Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   HQ617_RS01120 Genome accession   NZ_CP054055
Coordinates   189593..189892 (+) Length   99 a.a.
NCBI ID   WP_000234804.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS47     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 184593..194892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HQ617_RS01095 (HQ617_01095) - 186461..186826 (+) 366 WP_000285373.1 DUF1033 family protein -
  HQ617_RS01100 (HQ617_01100) comGA 186999..187970 (+) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  HQ617_RS01105 (HQ617_01105) comGB 187864..188907 (+) 1044 WP_223295889.1 competence type IV pilus assembly protein ComGB Machinery gene
  HQ617_RS01110 (HQ617_01110) comGC/cglC 188904..189233 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  HQ617_RS01115 (HQ617_01115) comGD 189208..189621 (+) 414 WP_000244261.1 competence type IV pilus minor pilin ComGD Machinery gene
  HQ617_RS01120 (HQ617_01120) comGE 189593..189892 (+) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE Machinery gene
  HQ617_RS01125 (HQ617_01125) comGF 189846..190307 (+) 462 WP_001878820.1 competence type IV pilus minor pilin ComGF Machinery gene
  HQ617_RS01130 (HQ617_01130) comGG 190285..190656 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG Machinery gene
  HQ617_RS01135 (HQ617_01135) comGH 190771..191745 (+) 975 WP_001008574.1 class I SAM-dependent methyltransferase Machinery gene
  HQ617_RS01140 (HQ617_01140) - 191777..192970 (+) 1194 WP_000047534.1 acetate kinase -
  HQ617_RS01145 (HQ617_01145) - 193122..193328 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  HQ617_RS01150 - 193387..193524 (+) 138 WP_001865900.1 hypothetical protein -
  HQ617_RS01155 (HQ617_01150) - 193565..194020 (+) 456 WP_000905673.1 hypothetical protein -
  HQ617_RS01160 (HQ617_01155) - 194089..194754 (+) 666 WP_000008113.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 99 a.a.        Molecular weight: 11377.53 Da        Isoelectric Point: 10.6093

>NTDB_id=397381 HQ617_RS01120 WP_000234804.1 189593..189892(+) (comGE) [Streptococcus agalactiae strain GBS47]
MVIIVRKKIRAYILLESLVGLAILVTITRLVISEINRQQSHIARRQHEQEVLILARMAVQTDQKILEANGVNIRIEESKN
KIVLFEDNKEILHVSKVKG

Nucleotide


Download         Length: 300 bp        

>NTDB_id=397381 HQ617_RS01120 WP_000234804.1 189593..189892(+) (comGE) [Streptococcus agalactiae strain GBS47]
GTGGTAATTATCGTAAGAAAGAAAATTAGAGCCTATATTTTACTGGAAAGCCTAGTGGGATTAGCTATTTTAGTTACTAT
TACAAGATTAGTAATAAGTGAAATAAATCGTCAACAATCCCATATTGCAAGAAGGCAACATGAGCAAGAAGTATTGATAT
TAGCTAGAATGGCTGTGCAAACTGATCAAAAAATATTAGAAGCAAATGGTGTTAATATTCGTATTGAAGAAAGTAAAAAT
AAAATTGTGCTCTTTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

39.583

96.97

0.384
  comGE Streptococcus mutans UA159

39.583

96.97

0.384

Multiple sequence alignment