Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SGGB_RS11070 Genome accession   NC_017576
Coordinates   2234673..2236505 (-) Length   610 a.a.
NCBI ID   WP_014620284.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 2229673..2241505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS11945 (SGGB_2170) - 2229912..2232347 (-) 2436 WP_014620280.1 putative cross-wall-targeting lipoprotein signal domain-containing proteiin -
  SGGB_RS11055 (SGGB_2171) - 2232375..2233130 (-) 756 WP_014620281.1 LPXTG cell wall anchor domain-containing protein -
  SGGB_RS11060 (SGGB_2172) - 2233145..2234212 (-) 1068 WP_014620282.1 hypothetical protein -
  SGGB_RS11065 (SGGB_2173) - 2234227..2234580 (-) 354 WP_014620283.1 TrbC/VirB2 family protein -
  SGGB_RS11070 (SGGB_2174) clpE 2234673..2236505 (-) 1833 WP_014620284.1 AAA family ATPase Regulator
  SGGB_RS11075 (SGGB_2175) - 2236507..2238255 (-) 1749 WP_014620285.1 type IA DNA topoisomerase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68356.36 Da        Isoelectric Point: 5.6553

>NTDB_id=39592 SGGB_RS11070 WP_014620284.1 2234673..2236505(-) (clpE) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MTNSSQTPFLEKYTDNLSAKIAQKETDYQVYGRDKEVAAVITSLRRRTKNNPVLVGEAGVGKTAIVEGLTLAILKGGVPE
DLQGLTVRSLELSSLMTGEDGGFIAKFKKIIEEMVATRGKNLLFIDEFHTIVGAGSQEGQALDAGNIIKPVLARGDIQLI
GATTLDEFHDYVETDRALERRMQPIMVDEPSQPQAIRMIDQAKRIYEDYHHIAISHEAVKQAVSLSVRYITDRFLPDKAF
DLIDEAATIASAEKKVIVTEYEIAQVLKNRTGIPITTILKADKDRLEDLTEKLKRRVKGQDEAISAIVDAITIAQAGLQD
ENKPISSFLFLGPTGVGKTELSKAVAEALFDDETAMIRFDMSEYKQKEDVVKFIGDRATRTKGQLTESVKQKPYSVLLLD
EVEKAHSEVMDIFLQVLDDGRLTDSTGRVISFKNTIVIMTTNIGAQKIINKAELKGNFKTLSERERLQFEKSMDSELQTE
FRPEFLNRIENKLIFNLLERDVIEEIAVKNLEEISERMAKQNLSLTYEPSLITYLSDVGTDVKNGARPLERLIKRKVLAP
IAIKSLELSKTDVTYHIHLWVKGKAPDQNHRQDQRQICLSVKDSLASLFS

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=39592 SGGB_RS11070 WP_014620284.1 2234673..2236505(-) (clpE) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGACCAACAGCTCCCAAACACCGTTCTTGGAAAAATACACCGATAACTTATCTGCTAAGATTGCACAAAAAGAGACTGA
TTATCAGGTTTACGGTCGTGACAAAGAGGTGGCGGCAGTTATCACCTCTCTTCGCAGACGTACTAAAAATAATCCTGTTT
TAGTCGGAGAAGCAGGTGTTGGGAAGACAGCTATTGTTGAAGGGTTGACTTTAGCGATTTTAAAAGGAGGAGTTCCAGAA
GACCTGCAAGGCTTAACCGTTCGTTCCTTAGAATTATCCAGTTTAATGACTGGCGAAGACGGTGGCTTTATTGCCAAATT
CAAAAAGATTATTGAAGAGATGGTGGCAACCCGTGGTAAAAATCTTCTCTTTATTGACGAATTTCATACCATTGTTGGAG
CAGGTAGCCAAGAGGGGCAGGCTCTTGATGCAGGAAATATCATTAAACCAGTGCTTGCCCGTGGCGATATTCAACTTATT
GGTGCCACTACCTTAGATGAATTTCATGACTATGTTGAAACCGACCGAGCTTTGGAGCGACGAATGCAGCCCATTATGGT
AGATGAACCCAGTCAGCCACAAGCCATCCGTATGATTGACCAAGCTAAAAGAATTTATGAAGACTATCATCATATTGCGA
TTAGTCACGAAGCGGTCAAGCAAGCGGTTAGTCTATCCGTACGTTATATCACTGATCGCTTTCTTCCTGATAAAGCATTC
GATTTAATCGATGAAGCAGCCACGATTGCGTCAGCTGAGAAAAAGGTAATCGTCACGGAGTATGAGATTGCTCAAGTCCT
TAAAAATCGCACAGGAATCCCTATCACAACGATTTTAAAAGCCGATAAGGACCGCTTAGAAGATTTAACGGAGAAACTTA
AACGGCGGGTGAAAGGACAAGATGAGGCGATTTCAGCCATTGTGGATGCCATTACTATTGCTCAAGCAGGGTTGCAGGAT
GAAAATAAGCCGATTTCGTCTTTCCTCTTTCTGGGGCCAACAGGTGTTGGGAAAACGGAACTGTCAAAAGCGGTTGCGGA
AGCGCTCTTTGATGATGAAACGGCCATGATTCGCTTTGATATGTCTGAATACAAGCAAAAAGAAGATGTGGTGAAATTTA
TCGGTGACAGGGCTACTCGCACCAAAGGTCAGCTAACAGAAAGTGTGAAACAAAAACCTTACAGTGTCTTATTACTTGAT
GAGGTTGAAAAAGCTCACAGTGAAGTGATGGATATTTTTCTTCAGGTGCTTGATGACGGCCGTCTAACCGATAGTACAGG
TCGAGTGATTAGTTTTAAAAATACCATTGTCATTATGACGACGAATATTGGGGCACAAAAGATTATTAATAAAGCAGAGT
TAAAAGGCAACTTTAAAACTCTTTCTGAGCGTGAACGCCTGCAATTTGAAAAATCGATGGATAGCGAACTACAAACTGAA
TTTCGTCCTGAGTTTCTCAACCGTATTGAAAACAAACTCATTTTTAACCTTTTGGAACGAGATGTCATTGAAGAAATTGC
GGTTAAAAATTTAGAGGAAATTTCAGAGCGGATGGCAAAACAAAATCTGAGTCTTACCTATGAACCAAGTTTAATCACTT
ACCTGTCTGATGTAGGAACTGATGTTAAAAATGGTGCTCGACCTTTGGAACGATTGATTAAGCGAAAAGTCTTAGCTCCT
ATTGCAATAAAGAGCTTAGAACTATCTAAAACCGATGTAACCTATCATATTCATCTCTGGGTTAAAGGGAAAGCACCAGA
CCAAAATCATAGGCAAGATCAACGGCAGATTTGTTTAAGTGTTAAGGACAGTTTAGCAAGTTTGTTTAGTTAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(323-490)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(498-566)

AAA lid domain (AAA_lid_9)

(192-266)

ATPase family associated with various cellular activities (AAA) (AAA)

(53-165)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

43.089

100

0.434
  clpE Streptococcus pneumoniae TIGR4

42.788

100

0.433
  clpE Streptococcus pneumoniae Rx1

42.788

100

0.433
  clpE Streptococcus pneumoniae D39

42.788

100

0.433
  clpE Streptococcus pneumoniae R6

42.788

100

0.433
  clpC Lactococcus lactis subsp. cremoris KW2

41.762

100

0.42
  clpC Streptococcus thermophilus LMD-9

41.946

97.705

0.41
  clpC Streptococcus thermophilus LMG 18311

41.611

97.705

0.407
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

39.903

100

0.405
  clpC Streptococcus mutans UA159

40.667

98.361

0.4
  clpC Streptococcus pneumoniae Rx1

40.464

98.852

0.4
  clpC Streptococcus pneumoniae D39

40.464

98.852

0.4
  clpC Streptococcus pneumoniae TIGR4

40.299

98.852

0.398