Detailed information NTG0039419

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: STND_RS07760
• Genome accession: NC_017563
• Coordinates: 1479610..1480395 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus ND03
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1474610..1485395

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STND_RS07730 (STND_1563)	gatC	1474672..1474974 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
STND_RS07735 (STND_1564)	-	1475114..1475368 (-)	255	WP_024010053.1	glycosyl transferase	-
STND_RS10460 (STND_1565)	-	1475381..1475590 (-)	210	WP_080998437.1	glycosyltransferase	-
STND_RS07740 (STND_1566)	-	1475906..1477350 (-)	1445	Protein_1467	6-phospho-beta-glucosidase	-
STND_RS07745 (STND_1567)	msrA	1477503..1478012 (-)	510	WP_041827375.1	peptide-methionine (S)-S-oxide reductase MsrA	-
STND_RS07750 (STND_1568)	-	1478024..1478872 (-)	849	WP_014608646.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
STND_RS07755 (STND_1569)	-	1478996..1479547 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
STND_RS07760 (STND_1570)	codY	1479610..1480395 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
STND_RS07765 (STND_1571)	-	1480655..1481869 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
STND_RS07770 (STND_1572)	-	1482224..1482676 (+)	453	WP_002946987.1	universal stress protein	-
STND_RS11765	-	1482856..1483427 (+)	572	Protein_1474	IS30 family transposase	-
STND_RS11305 (STND_1574)	-	1483499..1483672 (-)	174	WP_011681546.1	hypothetical protein	-
STND_RS07780 (STND_1575)	-	1483733..1484107 (-)	375	WP_011681547.1	membrane protein	-
STND_RS07785 (STND_1576)	pflA	1484319..1485119 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=39419 STND_RS07760 WP_002951720.1 1479610..1480395(-) (codY) [Streptococcus thermophilus ND03]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=39419 STND_RS07760 WP_002951720.1 1479610..1480395(-) (codY) [Streptococcus thermophilus ND03]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502