Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   HPC60_RS10045 Genome accession   NZ_CP053671
Coordinates   2019660..2020439 (-) Length   259 a.a.
NCBI ID   WP_023189059.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain G121     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2014660..2025439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPC60_RS10025 (HPC60_04770) pflA 2015386..2016180 (-) 795 WP_003130318.1 pyruvate formate-lyase-activating protein -
  HPC60_RS10030 (HPC60_04775) - 2016398..2017735 (-) 1338 WP_021722264.1 hemolysin family protein -
  HPC60_RS10035 (HPC60_04780) - 2017857..2018972 (-) 1116 WP_023189057.1 AI-2E family transporter -
  HPC60_RS10040 (HPC60_04785) - 2019121..2019569 (+) 449 Protein_1988 GNAT family N-acetyltransferase -
  HPC60_RS10045 (HPC60_04790) endA 2019660..2020439 (-) 780 WP_023189059.1 DNA/RNA non-specific endonuclease Machinery gene
  HPC60_RS10050 (HPC60_04795) - 2020633..2021529 (-) 897 Protein_1990 peptidoglycan amidohydrolase family protein -
  HPC60_RS10060 (HPC60_04805) - 2021641..2021895 (-) 255 WP_023189062.1 phage holin -
  HPC60_RS10065 (HPC60_04810) - 2021885..2022175 (-) 291 WP_124175219.1 hypothetical protein -
  HPC60_RS10070 (HPC60_04815) - 2022392..2022685 (+) 294 WP_025017162.1 hypothetical protein -
  HPC60_RS10075 (HPC60_04820) - 2022715..2024955 (-) 2241 WP_179107689.1 glycoside hydrolase domain-containing protein -
  HPC60_RS10080 (HPC60_04825) - 2025055..2025402 (-) 348 WP_023189066.1 DUF722 domain-containing protein -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 29113.10 Da        Isoelectric Point: 9.3107

>NTDB_id=393371 HPC60_RS10045 WP_023189059.1 2019660..2020439(-) (endA) [Lactococcus lactis subsp. lactis strain G121]
MKNKKIIPLLIVSIFILGGCANSQSDMDKSNHKWSQKDKTPSEELAKSVLTSSIKEQLKTDNIKFDHGSFIVNNNNNDLA
IINVVDPYAKNEIDIQGRPYLGEAVLPKSIQNNEKDNKDEKVIPQFGWGQKSNLKGFYKKAYTKGFLLNSKLIGGVKDFN
DSGSNMENIFTQTVWASEANDSSSKGQKYFENMIHKVQDKNMIIKYRVKALYVGSNLVPSGTEIEAKSDDFSLEIHVFIP
NVQPNLKVDYKTGQVTEVK

Nucleotide


Download         Length: 780 bp        

>NTDB_id=393371 HPC60_RS10045 WP_023189059.1 2019660..2020439(-) (endA) [Lactococcus lactis subsp. lactis strain G121]
ATGAAGAACAAAAAAATTATCCCATTACTGATTGTCAGCATTTTTATCTTAGGGGGCTGTGCTAACAGTCAATCTGATAT
GGATAAAAGTAATCATAAATGGAGTCAAAAAGATAAGACACCCTCAGAAGAACTCGCAAAAAGTGTTCTGACTTCTTCAA
TAAAAGAACAATTAAAAACAGATAACATAAAATTTGATCACGGTTCATTTATCGTTAATAATAATAACAATGATTTAGCA
ATTATTAATGTTGTAGACCCATACGCTAAGAATGAAATAGATATTCAAGGGCGTCCTTATTTGGGTGAAGCAGTTCTCCC
AAAATCTATTCAAAATAATGAAAAGGATAATAAAGATGAAAAAGTGATTCCTCAATTTGGTTGGGGACAAAAATCTAACT
TGAAAGGCTTCTATAAAAAAGCTTATACTAAAGGTTTTTTGCTAAATAGCAAACTAATAGGTGGCGTTAAAGATTTCAAT
GATAGCGGGTCAAATATGGAAAATATATTTACTCAAACGGTTTGGGCGAGTGAAGCTAATGATTCAAGTTCCAAGGGACA
AAAATATTTTGAAAATATGATTCATAAAGTTCAAGATAAGAATATGATCATCAAGTATAGAGTGAAAGCACTCTATGTTG
GAAGTAACCTTGTCCCATCAGGAACTGAAATAGAAGCAAAATCTGATGATTTTTCACTCGAGATACATGTTTTTATTCCA
AATGTTCAACCAAATCTTAAAGTAGATTATAAAACAGGTCAGGTCACTGAAGTCAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

42.174

88.803

0.375
  endA Streptococcus pneumoniae D39

42.174

88.803

0.375
  endA Streptococcus pneumoniae R6

42.174

88.803

0.375
  endA Streptococcus pneumoniae TIGR4

42.174

88.803

0.375