Detailed information NTG0390366

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: HKM25_RS00310
• Genome accession: NZ_CP053210
• Coordinates: 52987..53880 (+)
• Length: 297 a.a.
• NCBI ID: WP_000343888.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 6A-10
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 47987..58880

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HKM25_RS00280 (HKM25_56)	-	48300..49469 (+)	1170	WP_000366343.1	pyridoxal phosphate-dependent aminotransferase	-
HKM25_RS00285 (HKM25_57)	recO	49466..50236 (+)	771	WP_000616159.1	DNA repair protein RecO	Machinery gene
HKM25_RS00290 (HKM25_58)	plsX	50233..51225 (+)	993	WP_000717456.1	phosphate acyltransferase PlsX	-
HKM25_RS00295 (HKM25_59)	-	51231..51464 (+)	234	WP_000136447.1	acyl carrier protein	-
HKM25_RS00300 (HKM25_60)	-	51510..51800 (+)	291	Protein_52	transposase family protein	-
HKM25_RS11450	blpU	52003..52233 (+)	231	Protein_53	bacteriocin-like peptide BlpU	-
HKM25_RS11880 (HKM25_62)	-	52236..52361 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
HKM25_RS11455	-	52772..52966 (+)	195	WP_000756776.1	hypothetical protein	-
HKM25_RS00310 (HKM25_63)	comR	52987..53880 (+)	894	WP_000343888.1	XRE family transcriptional regulator	Regulator
HKM25_RS00315 (HKM25_64)	-	54410..54706 (+)	297	WP_000837726.1	uberolysin/carnocyclin family circular bacteriocin	-
HKM25_RS00320 (HKM25_65)	-	54713..55849 (+)	1137	WP_000698828.1	hypothetical protein	-
HKM25_RS00325	-	55846..56328 (+)	483	WP_001232094.1	stage II sporulation protein M	-
HKM25_RS00330 (HKM25_66)	-	56325..56921 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
HKM25_RS00335 (HKM25_67)	-	56902..57393 (+)	492	WP_000671990.1	hypothetical protein	-

Sequence

Protein

• Length: 297 a.a.
• Molecular weight: 34517.01 Da
• Isoelectric Point: 4.6498

>NTDB_id=390366 HKM25_RS00310 WP_000343888.1 52987..53880(+) (comR) [Streptococcus pneumoniae strain 6A-10]
MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENGQALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFL
KLKDELIHSQTYADKGRIERKEAILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQTEDSLIYIQTFEKIIAKTRHVF
YRPHLFLLKAKYALFVDKNILEAESFYEKAISLAELLDDQVLVQRILAEKQIDFPTT

Nucleotide

• Length: 894 bp

>NTDB_id=390366 HKM25_RS00310 WP_000343888.1 52987..53880(+) (comR) [Streptococcus pneumoniae strain 6A-10]
ATGGATGAGTTGAAACGTGAAATTGGTTATAAAATCAAAACTATTAGGCGATCTTGTGGAAAAACTCAGATAGATATTTG
TGGTGATGAATCAGAGTTGACGATTCGTCAGCTAGCACGTATTGAAAATGGGCAAGCTTTAGCAACACTTCCTAAATTAT
TATTGATTGCGGATAAACTTGGAGTATCATTACAGAATATTGTGGATGTTAAGGTTATAGAGATTCCAAAAGGATTCCTA
AAACTCAAAGATGAGCTGATTCATTCTCAAACCTACGCTGATAAGGGAAGAATCGAACGAAAAGAAGCTATACTTGAGGA
AATATATGAAAACTATTATGAGAATTTGCCTGAGGAAGAGCAGTTAATTGTGGATGTGACACAAGCTCGTTTTGATATTT
ATGGTAGTTCAGATGTGACCTACGGTTTAGGGTTAGTGGAAGAATATTTCCAGCAGTTATTAAAAAAGAAATATTTTTCT
GTAAATGATTTGTTGATTATTGAATTGTATTTCTTTTGTTGTGCTATGGGATTAGAAGATAAAGAACATTTTGAGGAGTT
AGCTCAAAAAGTATTGCTATGTTCAGAATATGAAGATAAGGCTAGCCTAGTTCAAATGGAAAAAGTTCTTCTGAGCCTAT
TTATCCAAATTCAGACAGAGGATAGTCTGATATATATTCAAACATTTGAGAAAATTATTGCTAAAACAAGACATGTTTTT
TACCGACCTCATCTATTTTTGCTAAAGGCAAAATATGCTTTATTTGTAGACAAGAATATTTTAGAGGCAGAAAGTTTCTA
TGAAAAGGCGATTTCTCTAGCAGAATTGCTAGACGATCAGGTATTAGTTCAGAGAATTTTAGCAGAAAAACAGATAGATT
TCCCAACAACCTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (76-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	36.667	100	0.37