Detailed information NTG0390225

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: HLB24_RS06135
• Genome accession: NZ_CP053183
• Coordinates: 1285457..1288075 (+)
• Length: 872 a.a.
• NCBI ID: WP_000073335.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain Guangzhou-SAU071
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1280457..1293075

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HLB24_RS06110 (HLB24_06110)	-	1281338..1282204 (+)	867	WP_000190137.1	2-oxoacid:ferredoxin oxidoreductase subunit beta	-
HLB24_RS06115 (HLB24_06115)	-	1282299..1282592 (+)	294	WP_000655666.1	MTH1187 family thiamine-binding protein	-
HLB24_RS06120 (HLB24_06120)	miaB	1282726..1284270 (+)	1545	WP_001001522.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
HLB24_RS06125 (HLB24_06125)	-	1284271..1284636 (+)	366	WP_000282386.1	RicAFT regulatory complex protein RicA family protein	-
HLB24_RS06130 (HLB24_06130)	thiW	1284663..1285154 (+)	492	WP_000842276.1	energy coupling factor transporter S component ThiW	-
HLB24_RS06135 (HLB24_06135)	hexA	1285457..1288075 (+)	2619	WP_000073335.1	DNA mismatch repair protein MutS	Machinery gene
HLB24_RS06140 (HLB24_06140)	hexB	1288088..1290097 (+)	2010	WP_000516254.1	DNA mismatch repair endonuclease MutL	Machinery gene
HLB24_RS06145 (HLB24_06145)	-	1290103..1290645 (+)	543	WP_001077635.1	glycerol-3-phosphate responsive antiterminator	-
HLB24_RS06150 (HLB24_06150)	-	1291119..1291937 (+)	819	WP_001103747.1	MIP/aquaporin family protein	-

Sequence

Protein

• Length: 872 a.a.
• Molecular weight: 99997.75 Da
• Isoelectric Point: 4.6351

>NTDB_id=390225 HLB24_RS06135 WP_000073335.1 1285457..1288075(+) (hexA) [Staphylococcus aureus strain Guangzhou-SAU071]
MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNN
GYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATL
LNEITTINPNEVVINDNISDHLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVV
QYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIER
DTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQDTLVHVNQLEPLDDLLDILEQSLVEEPP
ISVKDGGLFKVGFNMQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQ
TLSNAERFITDELKEKEDIILGAEDKAIELEYLLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFS
ENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQ
IFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHEL
TTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASADKKSSISNLKMI
ENEPEINQENSNLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMTPIEALVKLSELQNQLK

Nucleotide

• Length: 2619 bp

>NTDB_id=390225 HLB24_RS06135 WP_000073335.1 1285457..1288075(+) (hexA) [Staphylococcus aureus strain Guangzhou-SAU071]
ATGTCTAATGTTACACCAATGATGCAGCAATATTTAAAAATAAAATCAGAATACCAAGATTGCTTATTATTTTTTAGACT
AGGTGATTTCTATGAAATGTTTTATGAAGATGCCAAGGAGGCATCACGTGTACTTGAAATTACTTTAACTAAAAGAGATG
CTAAAAAAGAAAATCCAATTCCGATGTGTGGTGTTCCGTATCATTCTGCAGATAGTTATATAGATACACTTGTTAATAAT
GGATATAAAGTAGCTATTTGTGAACAGATGGAAGATCCGAAACAAACGAAAGGTATGGTTAGACGTGAGGTAGTAAGAAT
TGTGACTCCAGGAACTGTGATGGAGCAAGGAGGTGTAGATGATAAACAAAATAACTATATTTTAAGTTTTGTTATGAATC
AACCTGAAATTGCGCTTAGTTACTGTGATGTTTCTACTGGCGAATTAAAGGTTACACATTTTAATGATGAAGCGACTTTA
TTAAATGAAATTACGACGATAAACCCTAACGAAGTTGTTATCAATGACAATATTTCCGATCATTTAAAAAGACAAATTAA
TATGGTGACAGAAACAATAACAGTCAGGGAAACGTTATCATCTGAAATTTATAGTGTGAATCAAACTGAACATAAATTAA
TGTATCAAGCGACACAATTATTGCTAGATTATATTCATCATACACAAAAACGTGATTTATCGCATATCGAGGATGTTGTT
CAATATGCAGCTATAGATTATATGAAAATGGATTTTTATGCTAAGAGAAACCTTGAGTTAACGGAAAGCATTCGATTAAA
ATCCAAAAAAGGAACGCTACTTTGGTTGATGGACGAAACGAAAACACCAATGGGAGCACGCCGATTAAAACAATGGATAG
ATAGACCACTAATAAGTAAAGAACAAATTGAAGCACGATTAGATATCGTTGATGAATTTAGTGCTCATTTCATAGAAAGA
GACACCTTAAGAACATATCTTAATCAAGTGTATGATATTGAACGTCTTGTTGGGCGTGTTAGTTACGGAAATGTTAATGC
GAGAGATTTAATTCAACTTAAACATTCCATTTCTGAAATACCGAACATTAAAGCATTACTAAATTCTATGAATCAGGATA
CTCTTGTACATGTTAATCAACTAGAGCCACTTGATGATTTACTTGATATATTAGAACAGAGTTTAGTAGAAGAACCACCA
ATTTCAGTTAAAGATGGTGGACTATTCAAAGTTGGTTTTAATATGCAATTAGATGAATATCTTGAAGCTTCAAAAAACGG
AAAAACATGGTTAGCAGAACTACAAGCAAAAGAAAGACAACGTACAGGAATAAAATCATTGAAAATAAGCTTTAATAAAG
TGTTTGGTTATTTTATAGAAATAACACGTGCCAACTTGCAAAATTTTGAACCAAGTGAATTTGGTTATATGAGGAAGCAA
ACGCTATCGAATGCGGAACGATTTATAACTGATGAACTTAAAGAAAAAGAAGATATCATTTTAGGTGCGGAAGACAAAGC
CATTGAATTAGAATATCTATTATTTGTTCAGCTACGTGAAGAAGTTAAAAAATATACTGAACGTTTACAACAACAAGCTA
AAATTATTTCAGAGTTAGATTGTTTACAGAGCTTTGCAGAAATTGCTCAAAAATATAATTATACTAGGCCTTCATTTAGT
GAAAATAAAACATTAGAATTAGTGGAATCTAGGCACCCAGTAGTGGAAAGAGTAATGGATTATAATGACTATGTGCCTAA
TAATTGTCGATTAGATAATGAAACATTTATATATTTAATTACAGGTCCGAATATGTCTGGTAAATCGACGTATATGAGAC
AAGTTGCCATAATTAGCATAATGGCCCAAATGGGAGCTTATGTCCCTTGTAAAGAGGCTGTGTTACCTATATTTGATCAA
ATATTTACTAGAATAGGTGCGGCAGATGATTTGGTTTCAGGTAAGAGTACGTTTATGGTAGAAATGCTAGAAGCACAAAA
GGCATTAACTTATGCAACAGAGGATAGTTTGATTATTTTCGATGAAATTGGACGTGGTACTTCAACGTATGACGGTTTAG
CTTTAGCGCAGGCAATGATAGAGTATGTAGCTGAAACATCACATGCTAAAACGTTATTTTCAACACATTATCATGAATTG
ACAACATTAGATCAAGCATTACCAAGTCTAAAAAATGTTCACGTCGCTGCTAATGAATATAAAGGTGAACTTATATTCTT
GCATAAAGTCAAAGATGGTGCAGTTGACGATAGTTATGGTATTCAAGTTGCGAAATTAGCTGATTTACCTGAAAAAGTTA
TTAGCAGAGCACAAGTGATCCTAAGCGAGTTTGAAGCGTCTGCTGATAAAAAATCATCGATATCAAATTTAAAAATGATC
GAAAATGAACCTGAAATTAATCAAGAAAATTCAAACTTAAGTGTTGAAGAAACAACTGATACTTTATCTCAAAAAGACTT
TGAACAAGCATCATTTGATTTGTTTGAAAATGATCAAGAAAGCGAGATTGAACTACAAATTAAAAATTTGAATTTATCTA
ATATGACACCAATTGAGGCATTGGTGAAGTTAAGTGAATTACAAAATCAATTAAAATAG

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (125-237)

• MutS domain I (MutS_I) (5-115)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (412-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	45.455	100	0.459