Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   LPB220_RS04295 Genome accession   NZ_CP044230
Coordinates   813533..814372 (+) Length   279 a.a.
NCBI ID   WP_150905754.1    Uniprot ID   A0A5J6LLK6
Organism   Streptococcus sp. LPB0220     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 808533..819372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB220_RS04265 (LPB220_04265) - 808787..809668 (+) 882 WP_014713090.1 F0F1 ATP synthase subunit gamma -
  LPB220_RS04270 (LPB220_04270) atpD 809754..811160 (+) 1407 WP_013903321.1 F0F1 ATP synthase subunit beta -
  LPB220_RS04275 (LPB220_04275) - 811174..811593 (+) 420 WP_003002471.1 F0F1 ATP synthase subunit epsilon -
  LPB220_RS04280 (LPB220_04280) - 811692..811922 (+) 231 WP_013903322.1 DUF1146 family protein -
  LPB220_RS04285 (LPB220_04285) murA 811989..813272 (+) 1284 WP_150905750.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  LPB220_RS04290 (LPB220_04290) - 813262..813450 (+) 189 WP_049486327.1 DNA-directed RNA polymerase subunit beta -
  LPB220_RS04295 (LPB220_04295) endA 813533..814372 (+) 840 WP_150905754.1 DNA/RNA non-specific endonuclease Machinery gene
  LPB220_RS04300 (LPB220_04300) - 814454..815176 (+) 723 WP_150905757.1 matrixin family metalloprotease -
  LPB220_RS04305 (LPB220_04305) - 815281..817188 (+) 1908 WP_150905760.1 ABC-F family ATP-binding cassette domain-containing protein -
  LPB220_RS04310 (LPB220_04310) - 817246..817599 (+) 354 WP_150905762.1 hypothetical protein -
  LPB220_RS04315 (LPB220_04315) - 817604..818476 (+) 873 WP_150905765.1 XRE/MutR family transcriptional regulator -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30436.90 Da        Isoelectric Point: 9.4817

>NTDB_id=388993 LPB220_RS04295 WP_150905754.1 813533..814372(+) (endA) [Streptococcus sp. LPB0220]
MTKQTVTKRTKQTLAGFVVATALAIGGYYFNQPTVKEATDQVVSVVTSSQNETPSKELASSVLTKSARSQLGNELEWNGA
GAFVVKGNRTDLDASVASQPYADNKTKEVNGKTLPTVANALMSKATRQYRDRDATGSGLTDWKPAGWHQVHNLSGEYDHA
VDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWSNQANDPHSTGQNYYETLVRKALDKNKRIRYRVTLIYNQPEDLIPL
GSQIEAKSSDGTLEFNVFVPNVQSGISLDYQTGKVTVHQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=388993 LPB220_RS04295 WP_150905754.1 813533..814372(+) (endA) [Streptococcus sp. LPB0220]
ATGACAAAACAAACAGTAACCAAACGAACCAAACAAACACTAGCTGGGTTTGTGGTGGCAACAGCCCTAGCAATCGGTGG
TTATTATTTTAACCAACCGACGGTAAAAGAAGCGACAGATCAGGTTGTTTCCGTAGTGACCAGTAGCCAAAATGAAACAC
CGAGTAAGGAATTAGCCAGCTCGGTGCTAACGAAATCTGCCCGTTCGCAATTGGGAAATGAGTTGGAATGGAATGGTGCT
GGTGCCTTTGTCGTTAAGGGGAATCGAACAGATCTGGATGCCAGTGTTGCTAGTCAACCTTATGCGGATAACAAGACTAA
AGAAGTGAATGGAAAGACCCTACCGACAGTTGCCAATGCCCTCATGAGTAAGGCGACGCGGCAGTATAGAGATCGCGATG
CAACAGGAAGTGGACTAACCGATTGGAAACCAGCAGGCTGGCATCAGGTCCACAATCTGTCTGGCGAGTATGACCATGCG
GTAGATCGGGGCCACCTATTGGGCTATGCCTTGATCGGTAATCTCAAAGGGTTTGATGCTTCGACTAGTAATCCCAAAAA
TATCGCTGTACAAACGGCCTGGTCCAATCAAGCTAATGATCCTCATTCTACTGGTCAAAACTACTATGAGACCCTAGTCC
GAAAGGCACTGGATAAGAACAAGCGGATCCGCTATCGGGTCACCTTGATCTACAATCAGCCGGAAGATCTGATTCCTTTA
GGATCACAGATCGAAGCCAAATCGAGTGATGGAACCCTTGAGTTTAATGTTTTTGTTCCTAATGTTCAAAGTGGGATTAG
CCTGGATTACCAGACAGGAAAAGTAACCGTTCATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-251)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5J6LLK6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

64.364

98.566

0.634
  endA Streptococcus pneumoniae D39

64.364

98.566

0.634
  endA Streptococcus pneumoniae R6

64.364

98.566

0.634
  endA Streptococcus pneumoniae TIGR4

64.364

98.566

0.634

Multiple sequence alignment