Detailed information NTG0388878

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: F5989_RS09485
• Genome accession: NZ_CP044221
• Coordinates: 1873374..1874255 (+)
• Length: 293 a.a.
• NCBI ID: WP_002266944.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain NCH105
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1868374..1879255

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F5989_RS09455 (F5989_09635)	-	1868557..1869435 (+)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-
F5989_RS09460 (F5989_09640)	atpD	1869461..1870867 (+)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
F5989_RS09465 (F5989_09645)	-	1870881..1871297 (+)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
F5989_RS09470 (F5989_09650)	-	1871571..1871804 (+)	234	WP_002285829.1	DUF1146 family protein	-
F5989_RS09475 (F5989_09655)	murA	1871870..1873141 (+)	1272	WP_002273074.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
F5989_RS09480 (F5989_09660)	-	1873144..1873332 (+)	189	WP_002264826.1	DNA-directed RNA polymerase subunit beta	-
F5989_RS09485 (F5989_09665)	endA	1873374..1874255 (+)	882	WP_002266944.1	DNA/RNA non-specific endonuclease	Machinery gene
F5989_RS09490 (F5989_09670)	-	1874323..1874973 (-)	651	WP_002262934.1	amino acid ABC transporter permease	-
F5989_RS09495 (F5989_09675)	-	1874988..1875692 (-)	705	WP_002262933.1	amino acid ABC transporter permease	-
F5989_RS09500 (F5989_09680)	-	1875710..1876522 (-)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
F5989_RS09505 (F5989_09685)	-	1876519..1877301 (-)	783	WP_002266943.1	amino acid ABC transporter ATP-binding protein	-
F5989_RS09510 (F5989_09690)	vicR	1877654..1878361 (+)	708	WP_002262930.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32169.80 Da
• Isoelectric Point: 9.5337

>NTDB_id=388878 F5989_RS09485 WP_002266944.1 1873374..1874255(+) (endA) [Streptococcus mutans strain NCH105]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYANNQTKIVQGQTVPTVANALLSKAIRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=388878 F5989_RS09485 WP_002266944.1 1873374..1874255(+) (endA) [Streptococcus mutans strain NCH105]
ATGACTAGAAAAACGAACAAGTCTCAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCTTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAATAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTATTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (104-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	63.675	79.863	0.509
endA	Streptococcus pneumoniae D39	63.675	79.863	0.509
endA	Streptococcus pneumoniae R6	63.675	79.863	0.509
endA	Streptococcus pneumoniae TIGR4	63.675	79.863	0.509