Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   HHM65_RS08960 Genome accession   NZ_CP051624
Coordinates   1801154..1801936 (-) Length   260 a.a.
NCBI ID   WP_003053880.1    Uniprot ID   A0A9X9SKT8
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1796154..1806936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM65_RS08930 (HHM65_08935) - 1796800..1797393 (-) 594 WP_274047907.1 helix-turn-helix transcriptional regulator -
  HHM65_RS08935 (HHM65_08940) - 1797624..1797923 (-) 300 WP_015058017.1 rhodanese-like domain-containing protein -
  HHM65_RS08940 (HHM65_08945) - 1797916..1799568 (-) 1653 WP_015058018.1 FAD-dependent oxidoreductase -
  HHM65_RS08945 (HHM65_08950) - 1799586..1799924 (-) 339 WP_003061685.1 rhodanese-like domain-containing protein -
  HHM65_RS08950 (HHM65_08955) - 1800138..1800398 (+) 261 WP_003053835.1 metal-sensitive transcriptional regulator -
  HHM65_RS08955 (HHM65_08960) - 1800465..1801016 (-) 552 WP_170172089.1 isochorismatase family cysteine hydrolase -
  HHM65_RS08960 (HHM65_08965) codY 1801154..1801936 (-) 783 WP_003053880.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  HHM65_RS08965 (HHM65_08970) - 1802201..1803415 (-) 1215 WP_003060547.1 pyridoxal phosphate-dependent aminotransferase -
  HHM65_RS08970 (HHM65_08975) - 1803752..1804204 (+) 453 WP_003052566.1 universal stress protein -
  HHM65_RS08975 (HHM65_08980) - 1804367..1805755 (-) 1389 WP_003052568.1 Cof-type HAD-IIB family hydrolase -
  HHM65_RS08980 (HHM65_08985) - 1805828..1806793 (+) 966 WP_003053845.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28748.89 Da        Isoelectric Point: 4.4678

>NTDB_id=385945 HHM65_RS08960 WP_003053880.1 1801154..1801936(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVESELTIFPVESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDNEFSDEDLILVEISSTVVGIQLLN
LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=385945 HHM65_RS08960 WP_003053880.1 1801154..1801936(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATTACGTCTATTCTACAGCGCTCTGTAGATAGCTTGGAGACAGAACTCCC
ATATAATACGATGGCGTCTCGCTTGGCAGATATTATTGACTGTAATGCCTGCATTATCAATGGCGGAGGAACCCTACTTG
GTTATGCCATGAAATATAAAACCAACACAGACCGTGTTGAGGAATTTTTTGAAGCTAAGCAATTTCCAGATACTTATGTC
AAAGCAGCTAGCCGTGTCTACGACACTGAGGCCAATCTTTCAGTGGAAAGTGAATTAACCATTTTTCCTGTGGAATCGAA
AGACATCTATCCAGATGGTTTGACAACAATTGCACCGATTTATGGTGGAGGTATGCGTCTAGGATCTCTTATCATTTGGC
GCAACGATAATGAGTTTAGTGATGAGGACCTCATCTTGGTTGAAATTTCAAGCACGGTTGTTGGGATTCAGTTGTTAAAC
CTTCAAACAGAAAACCTGGAAGAAACGATCCGCAAGCAAACTGCTGTCAACATGGCTATTAACACCCTATCTTATTCAGA
AATGAAGGCTGTTGCAGCTATTCTTGGTGAATTGGATGGTAACGAAGGGCGTTTAACAGCTTCTGTCATTGCTGACCGTA
TTGGCATTACACGATCTGTGATCGTCAATGCCCTTCGTAAATTGGAAAGTGCTGGTATTATTGAAAGTCGCTCTCTCGGC
ATGAAGGGAACCTACCTCAAAGTTATTAATGAGGGTATTTTTGATAAATTGAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9SKT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.537

98.846

0.658
  codY Bacillus subtilis subsp. subtilis str. 168

53.036

95

0.504