Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   HEQ84_RS08305 Genome accession   NZ_CP050870
Coordinates   1616572..1618923 (+) Length   783 a.a.
NCBI ID   WP_024704006.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS6     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1611572..1623923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HEQ84_RS08285 (HEQ84_08300) - 1612226..1612477 (-) 252 WP_011226551.1 hypothetical protein -
  HEQ84_RS08290 (HEQ84_08305) - 1612580..1612807 (-) 228 WP_011681629.1 hypothetical protein -
  HEQ84_RS08295 (HEQ84_08310) - 1612794..1613108 (-) 315 WP_014608696.1 hypothetical protein -
  HEQ84_RS08300 (HEQ84_08315) polA 1613726..1616365 (-) 2640 WP_011681632.1 DNA polymerase I -
  HEQ84_RS08305 (HEQ84_08320) mutS/mutS2 1616572..1618923 (+) 2352 WP_024704006.1 endonuclease MutS2 Machinery gene
  HEQ84_RS08310 (HEQ84_08325) - 1619024..1619566 (-) 543 WP_002947866.1 CvpA family protein -
  HEQ84_RS08315 (HEQ84_08330) - 1619563..1619880 (-) 318 WP_002947863.1 hypothetical protein -
  HEQ84_RS08320 (HEQ84_08335) rnhC 1620194..1621084 (+) 891 WP_011681634.1 ribonuclease HIII -
  HEQ84_RS08325 (HEQ84_08340) lepB 1621103..1621726 (+) 624 WP_002947854.1 signal peptidase I -

Sequence

Protein


Download         Length: 783 a.a.        Molecular weight: 88063.41 Da        Isoelectric Point: 6.6236

>NTDB_id=381843 HEQ84_RS08305 WP_024704006.1 1616572..1618923(+) (mutS/mutS2) [Streptococcus thermophilus strain CS6]
MNTKILDQLEFNKVKDQFTEYLQTEQAQAELRDLVPMTNPERIQNQFTEIQEMSEIFVEHHGFAIGSLRDISEPLRRLEL
DADLNIQELIAIKKVLQASADLSRFYADLENVELIALKRLFEKIEAFPSLQGSLQSINDGGFIEHFASPELQNIRRQLKA
CDDAIRQTLQDILKKSGHMLAENLIASRNGRSVLPVKNTYRNRIAGVVHDISSSGNTVYIEPRAVIQLNEKITQLRADER
HEMARILHELSDQLRPHTAAIANNAWILGHMDFIRGKYLYLHDKKAIIPEISDNQTLQLLNVRHPLLINPVANDLRFDED
LTVIVITGPNTGGKTVMLKTLGLAQLMAQSGLPILADKGSRVAIFQEIFADIGDEQSIEQSLSTFSSHMTHIVEILNTAD
SNSLVLVDELGAGTDPQEGASLAMAILEHLRLSQIKTMATTHYPELKAYGIETQHVENASMEFDTATLRPTYRFMQGVPG
RSNAFEIARRLGLNEIIVKEAENLTDTDSDVNRIIEQLESQTVETQKRLEHIKDVEQENLKFNRAVKKLYNEFSHEYDKE
LEKAQKEIQEMVDTALAESDSILKNLHDKSQLKPHEVIDAKGKLKKLAAQVDLSKNKVLRKAKKEKAARAPRVGDDIIVT
AYGQRGTLTSQAKNGNWEAQVGLIKMSLKADEFTLVRAQAEAQQPKKKQINVVKKAKKTSSDGPRARLDLRGKRYEEAMQ
ELDAFIDQALLNNMSQVEIIHGIGTGVIRDAVTKYLRRHRHVKNFEYAPQSAGGSGCTIATLG

Nucleotide


Download         Length: 2352 bp        

>NTDB_id=381843 HEQ84_RS08305 WP_024704006.1 1616572..1618923(+) (mutS/mutS2) [Streptococcus thermophilus strain CS6]
ATGAACACAAAGATTTTAGACCAATTAGAATTTAACAAGGTCAAAGACCAGTTCACAGAATACCTGCAGACCGAACAGGC
TCAGGCGGAGTTACGTGACTTGGTGCCTATGACCAATCCAGAAAGAATTCAAAACCAATTTACAGAAATCCAAGAAATGT
CTGAGATTTTCGTAGAGCATCATGGCTTTGCCATTGGTAGCTTAAGAGATATTTCTGAGCCCTTGCGTCGCTTGGAACTG
GATGCTGACCTCAACATCCAGGAGCTCATTGCTATCAAGAAGGTCTTGCAAGCTTCAGCTGACCTTAGCCGCTTCTACGC
TGACCTTGAAAATGTTGAACTCATCGCTCTTAAACGTCTTTTTGAAAAGATTGAGGCCTTTCCAAGTCTACAAGGTAGTC
TTCAAAGTATTAATGATGGTGGTTTTATTGAGCATTTTGCTAGTCCTGAGTTGCAAAATATCCGTCGTCAACTTAAGGCT
TGTGATGATGCCATTCGCCAGACCTTGCAAGACATTCTCAAGAAATCTGGGCACATGTTAGCCGAGAACTTAATTGCTAG
TCGTAATGGCCGTTCAGTGCTTCCTGTCAAAAATACCTACCGTAACCGTATTGCGGGGGTTGTTCATGACATCTCAAGCT
CTGGGAACACAGTGTATATCGAGCCACGAGCCGTTATCCAGCTTAACGAAAAAATTACACAATTACGTGCAGACGAGCGC
CATGAGATGGCACGTATCCTACATGAACTGTCTGATCAACTCCGTCCACATACTGCTGCCATCGCTAACAACGCTTGGAT
TTTGGGCCATATGGACTTCATTAGAGGAAAATACCTCTATCTCCATGATAAAAAGGCAATTATTCCAGAGATTAGTGACA
ACCAAACACTCCAACTGCTTAACGTTCGTCACCCTCTTTTAATCAATCCAGTAGCCAACGATTTGCGCTTTGATGAGGAT
CTCACGGTCATTGTCATTACAGGTCCCAATACTGGTGGTAAAACGGTCATGCTTAAAACTCTAGGACTAGCTCAACTAAT
GGCTCAATCTGGTCTGCCAATTTTGGCTGATAAGGGCAGTCGTGTAGCCATTTTCCAAGAGATTTTTGCGGATATCGGAG
ACGAACAGTCTATCGAACAGAGCTTGTCAACTTTCTCTAGTCACATGACGCACATTGTCGAGATTTTGAACACTGCCGAC
AGCAATAGCTTGGTCTTGGTCGATGAGCTTGGGGCTGGTACCGACCCTCAGGAAGGGGCTAGTCTAGCCATGGCAATCCT
AGAGCACCTCCGTTTGAGCCAGATTAAGACCATGGCTACTACTCACTATCCTGAGCTTAAGGCCTATGGGATTGAGACAC
AACATGTGGAAAATGCTAGCATGGAGTTTGACACAGCAACTCTAAGACCTACCTATCGCTTTATGCAAGGGGTTCCTGGT
CGCTCTAACGCCTTTGAGATTGCTCGCCGCCTCGGTCTGAATGAGATTATTGTCAAGGAAGCAGAAAACCTCACTGATAC
GGATAGTGATGTCAACCGTATCATCGAGCAACTTGAATCCCAAACTGTAGAAACACAAAAACGTCTGGAGCACATCAAGG
ACGTTGAGCAAGAGAACCTTAAATTCAACCGTGCGGTCAAGAAACTCTATAATGAATTCTCCCATGAGTACGACAAGGAA
CTCGAAAAGGCTCAAAAAGAAATTCAAGAGATGGTGGATACAGCTTTAGCTGAAAGCGATAGTATTCTCAAAAATCTCCA
TGATAAGAGTCAACTCAAGCCTCATGAAGTTATCGACGCCAAAGGGAAACTTAAGAAACTTGCCGCACAAGTCGACCTTT
CTAAGAACAAGGTTCTTCGTAAAGCCAAGAAAGAAAAGGCTGCGCGTGCCCCTCGTGTCGGTGATGATATCATCGTTACT
GCCTATGGGCAACGTGGTACGCTCACCAGTCAAGCCAAAAATGGTAACTGGGAAGCTCAAGTGGGTCTCATCAAGATGAG
CCTAAAGGCAGACGAATTCACTCTGGTTCGTGCCCAAGCAGAAGCACAACAACCCAAGAAAAAACAAATTAATGTGGTTA
AAAAAGCCAAGAAGACATCTTCTGATGGGCCTCGTGCCCGTCTAGACCTTCGTGGGAAACGTTACGAAGAAGCCATGCAA
GAGCTCGATGCCTTTATTGACCAAGCTCTACTTAACAACATGAGTCAGGTGGAAATCATTCACGGTATTGGTACCGGTGT
CATCCGAGATGCTGTAACCAAATATCTCCGCCGTCATCGCCATGTTAAAAATTTTGAATATGCCCCACAAAGTGCTGGTG
GTTCCGGATGTACCATCGCAACCTTGGGTTAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(708-782)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-672)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.295

100

0.398

Multiple sequence alignment