Detailed information NTG0381832

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: HEQ84_RS07710
• Genome accession: NZ_CP050870
• Coordinates: 1493639..1494424 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain CS6
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1488639..1499424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HEQ84_RS07675 (HEQ84_07695)	gatC	1488704..1489006 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
HEQ84_RS07680 (HEQ84_07700)	-	1489146..1489400 (-)	255	WP_024010053.1	glycosyl transferase	-
HEQ84_RS07685 (HEQ84_07705)	-	1489413..1489610 (-)	198	WP_014608644.1	glycosyltransferase	-
HEQ84_RS07690 (HEQ84_07710)	-	1489938..1491379 (-)	1442	Protein_1472	6-phospho-beta-glucosidase	-
HEQ84_RS07695 (HEQ84_07715)	msrA	1491532..1492041 (-)	510	WP_024703984.1	peptide-methionine (S)-S-oxide reductase MsrA	-
HEQ84_RS07700 (HEQ84_07720)	-	1492053..1492901 (-)	849	WP_024703985.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
HEQ84_RS07705 (HEQ84_07725)	-	1493025..1493576 (-)	552	WP_002946999.1	isochorismatase family cysteine hydrolase	-
HEQ84_RS07710 (HEQ84_07730)	codY	1493639..1494424 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
HEQ84_RS07715 (HEQ84_07735)	-	1494684..1495898 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
HEQ84_RS07720 (HEQ84_07740)	-	1496253..1496705 (+)	453	WP_002946987.1	universal stress protein	-
HEQ84_RS07725 (HEQ84_07745)	-	1496885..1497456 (+)	572	Protein_1479	IS30 family transposase	-
HEQ84_RS07730 (HEQ84_07750)	-	1497528..1497701 (-)	174	WP_011681546.1	hypothetical protein	-
HEQ84_RS07735 (HEQ84_07755)	-	1497762..1498136 (-)	375	WP_011681547.1	membrane protein	-
HEQ84_RS07740 (HEQ84_07760)	pflA	1498348..1499148 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=381832 HEQ84_RS07710 WP_002951720.1 1493639..1494424(-) (codY) [Streptococcus thermophilus strain CS6]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=381832 HEQ84_RS07710 WP_002951720.1 1493639..1494424(-) (codY) [Streptococcus thermophilus strain CS6]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502