Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   HB750_RS00605 Genome accession   NZ_CP050273
Coordinates   123870..126200 (+) Length   776 a.a.
NCBI ID   WP_019804900.1    Uniprot ID   -
Organism   Streptococcus mutans strain P1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 118870..131200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB750_RS00580 (HB750_00580) lepB 119940..120528 (-) 589 Protein_113 signal peptidase I -
  HB750_RS00585 (HB750_00585) rnhC 120548..121459 (-) 912 WP_032526365.1 ribonuclease HIII -
  HB750_RS00590 (HB750_00590) - 121655..121960 (+) 306 WP_002263360.1 hypothetical protein -
  HB750_RS00595 (HB750_00595) - 121957..122502 (+) 546 WP_002271344.1 CvpA family protein -
  HB750_RS00600 (HB750_00600) - 122905..123651 (+) 747 WP_002264188.1 CPBP family intramembrane glutamic endopeptidase -
  HB750_RS00605 (HB750_00605) mutS/mutS2 123870..126200 (+) 2331 WP_019804900.1 endonuclease MutS2 Machinery gene
  HB750_RS00610 (HB750_00610) trxA 126275..126589 (+) 315 WP_002263363.1 thioredoxin -
  HB750_RS00615 (HB750_00615) - 126687..127736 (+) 1050 WP_014835036.1 zinc-dependent alcohol dehydrogenase family protein -
  HB750_RS00620 (HB750_00620) mutY 127928..129073 (-) 1146 WP_002265472.1 A/G-specific adenine glycosylase -
  HB750_RS00625 (HB750_00625) - 130110..130313 (-) 204 WP_019804899.1 hypothetical protein -
  HB750_RS00630 (HB750_00630) - 130618..130863 (+) 246 WP_019804898.1 hypothetical protein -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87700.99 Da        Isoelectric Point: 6.4838

>NTDB_id=377957 HB750_RS00605 WP_019804900.1 123870..126200(+) (mutS/mutS2) [Streptococcus mutans strain P1]
MNTKILKALEFDKVKKQFAHFLQSEQGQMELNDLLPMTNQEKIERSFAEIADVAQIFQEYASFGFGHSQDISESLRRLEL
GADLNTQELLAVKRILQMSAELKDFYDNLENVDLQILDCLFEKIETFPDLQGSLQAINDGGFIEDFASPELTKIRHHIHQ
NEQQIRQILQEMLKKQGDLLAENLIASRSGRSVLPVKNTYRHRIAGVVHDISASGNTVYIEPRAVVNLNEEMTQARADER
HEMTRILHDLSDRLRSQTDIIGNNAWLLGHIDFVRGKYLYMRENQASLPSLTTDQTIRLLSVRHPLLSNPIANDLHFEHD
TTAILITGPNTGGKTIMLKTLGITQLMAQSGLPILADEGSKVAVFKDIFADIGDEQSIEQSLSTFSSHMTHIVEILQKAN
KDSLVLFDELGAGTDPQEGAALAMSILEHLRLSDIKTMITTHYPELKAYGIETEFIENASMEFDMVTLSPTYHFMQGVPG
RSNAFEIARRLGLSEIIVAEAENLTNTDSDVNKIIERLENQTIESRRRLDNIREVEQENLKFNRAVKKLYNEFSHAQDKE
LRKAKLKAQEIVDKALAESDFILKNLQDKAQLKPHEIIEAKGKLKQLAPEIELSKNKVLKKAKKKRAAKVGDDIIVSSYG
QRGTLTKRFKDGRWEAQVGLIKMTLQESEFDLVKSDKAQASQKRQAHLVKRTSQKAPSARLDLRGKRYEEAMQELDEFID
QALLNNMAQVDIIHGIGTGVIRDGVTKYLHRNKQVKEFGYAPQNAGGSGVTIVTFK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=377957 HB750_RS00605 WP_019804900.1 123870..126200(+) (mutS/mutS2) [Streptococcus mutans strain P1]
ATGAATACAAAGATTTTAAAAGCCTTAGAATTTGATAAGGTTAAAAAGCAATTTGCTCATTTTTTGCAGAGTGAGCAAGG
GCAAATGGAATTAAACGATTTATTACCTATGACCAATCAGGAAAAAATTGAACGTTCTTTTGCCGAAATTGCAGATGTAG
CACAGATTTTTCAGGAATATGCTTCCTTTGGCTTTGGGCACAGTCAGGATATTTCAGAAAGTTTACGTCGTTTAGAATTA
GGAGCGGATCTCAATACTCAAGAGCTTTTGGCTGTCAAACGTATTTTGCAGATGTCAGCAGAGCTCAAGGACTTTTATGA
TAATTTAGAAAATGTTGATTTGCAAATTTTGGATTGCTTATTTGAAAAGATTGAAACGTTTCCTGATTTGCAAGGGAGTT
TACAAGCCATCAATGATGGTGGCTTTATTGAAGATTTTGCTAGTCCTGAATTAACTAAAATTCGTCATCATATTCACCAA
AATGAACAACAAATTCGTCAAATTCTTCAGGAAATGTTGAAGAAACAAGGTGATTTATTGGCTGAAAACCTTATTGCCAG
TCGCAGTGGTCGCAGTGTTCTTCCAGTGAAAAATACTTATCGTCATCGTATTGCAGGTGTTGTTCATGATATTTCAGCTT
CAGGAAATACGGTTTACATTGAACCTCGAGCTGTTGTTAATTTAAATGAAGAGATGACTCAGGCGCGTGCAGACGAACGC
CATGAAATGACTCGCATTTTACATGATTTATCCGATAGGCTAAGATCACAAACAGATATTATTGGTAATAATGCTTGGTT
GCTTGGACATATTGATTTTGTTCGTGGGAAATACCTTTATATGAGAGAAAATCAAGCCAGTCTTCCTAGTTTAACAACGG
ATCAAACTATCCGTCTTTTGAGTGTACGTCATCCTCTGCTAAGCAATCCAATTGCCAATGATTTACATTTTGAACATGAT
ACAACAGCCATTTTAATTACAGGTCCTAATACGGGCGGTAAAACCATCATGTTAAAAACATTGGGAATAACGCAACTGAT
GGCTCAGTCAGGTCTTCCTATTTTGGCTGATGAGGGAAGTAAGGTTGCTGTTTTTAAAGACATCTTTGCAGACATTGGTG
ATGAACAGTCCATTGAGCAAAGTTTATCCACTTTTTCAAGTCATATGACACATATTGTCGAAATTCTGCAAAAGGCCAAT
AAAGACAGCTTAGTCCTTTTTGATGAACTTGGTGCTGGTACAGATCCACAAGAAGGGGCAGCCTTGGCCATGAGTATTCT
AGAACATTTACGCTTATCAGATATTAAAACAATGATTACCACCCATTATCCAGAGCTCAAGGCCTATGGTATCGAAACAG
AATTTATTGAAAATGCGAGTATGGAATTTGATATGGTGACGCTCAGCCCCACCTATCATTTTATGCAAGGAGTACCGGGA
CGATCCAATGCTTTTGAGATTGCACGTCGTTTAGGTTTGTCTGAAATTATTGTTGCAGAAGCGGAAAATTTGACGAATAC
GGATTCAGATGTTAATAAAATTATTGAACGTTTGGAAAATCAAACCATTGAAAGTCGCAGACGTTTGGATAATATTCGTG
AAGTGGAGCAGGAAAATCTCAAATTTAATCGAGCCGTCAAAAAACTTTATAATGAATTCTCACATGCACAAGACAAAGAG
TTGCGTAAGGCCAAACTAAAGGCTCAAGAGATTGTTGACAAGGCTCTTGCAGAGAGTGATTTTATTCTCAAAAATCTTCA
AGACAAAGCACAACTTAAGCCCCATGAAATTATTGAAGCTAAAGGCAAGCTCAAGCAGTTGGCTCCCGAGATAGAGCTTT
CGAAAAATAAGGTTCTTAAAAAAGCTAAGAAGAAACGTGCTGCGAAAGTTGGAGATGATATTATTGTCAGCAGTTATGGG
CAAAGAGGAACGCTTACTAAGCGCTTCAAAGATGGTCGTTGGGAAGCACAAGTAGGGTTGATCAAAATGACTTTACAAGA
GTCAGAGTTTGATTTAGTGAAATCAGACAAAGCCCAAGCATCGCAGAAAAGACAAGCTCACCTTGTCAAAAGGACTTCTC
AAAAGGCTCCTAGTGCTAGACTTGATTTACGTGGCAAGCGTTATGAAGAAGCGATGCAAGAATTAGATGAATTCATTGAT
CAGGCACTCTTGAACAATATGGCTCAGGTTGACATCATCCATGGTATCGGAACTGGTGTTATCCGTGATGGCGTAACTAA
ATATCTTCACCGTAATAAGCAAGTTAAGGAGTTTGGCTATGCTCCTCAAAATGCAGGTGGTTCGGGCGTTACAATCGTGA
CTTTCAAATAG

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(630-669)

Smr domain (Smr)

(701-776)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.102

100

0.407