Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   HB752_RS01025 Genome accession   NZ_CP050271
Coordinates   207745..208530 (+) Length   261 a.a.
NCBI ID   WP_002263472.1    Uniprot ID   P59388
Organism   Streptococcus mutans strain S1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 202745..213530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB752_RS01005 (HB752_01005) - 203499..204884 (+) 1386 WP_002274741.1 Cof-type HAD-IIB family hydrolase -
  HB752_RS01010 (HB752_01010) - 205162..205611 (-) 450 WP_002263469.1 universal stress protein -
  HB752_RS01015 (HB752_01015) - 205709..206245 (-) 537 WP_019323357.1 biotin transporter BioY -
  HB752_RS01020 (HB752_01020) - 206422..207636 (+) 1215 WP_025988447.1 pyridoxal phosphate-dependent aminotransferase -
  HB752_RS01025 (HB752_01025) codY 207745..208530 (+) 786 WP_002263472.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  HB752_RS01030 (HB752_01030) - 208532..209083 (+) 552 WP_002263473.1 isochorismatase family cysteine hydrolase -
  HB752_RS01035 (HB752_01035) aspS 209341..211092 (+) 1752 WP_002266297.1 aspartate--tRNA ligase -
  HB752_RS01040 (HB752_01040) gatC 211219..211521 (+) 303 WP_002263475.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  HB752_RS01045 (HB752_01045) gatA 211521..212987 (+) 1467 WP_002274738.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28970.13 Da        Isoelectric Point: 4.5032

>NTDB_id=377729 HB752_RS01025 WP_002263472.1 207745..208530(+) (codY) [Streptococcus mutans strain S1]
MANLLSKTRRITSILQRSVESLQSDLPYNTIADQLAEIIDCNACIIDGSGIILGYAMKYKTNTDRVEEFFQAKKLPDDYV
KSASRIYDTEANLSVENDLTIFPIESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDKEFNDDDLILIEISSTVVGIQLLN
LQTENLEETIRKQTAINMAINTLSYSEMKAVAAILNELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKDYS

Nucleotide


Download         Length: 786 bp        

>NTDB_id=377729 HB752_RS01025 WP_002263472.1 207745..208530(+) (codY) [Streptococcus mutans strain S1]
ATGGCTAATTTATTATCGAAAACGCGACGTATTACATCCATTTTACAACGCTCGGTTGAGAGCCTTCAAAGTGATTTGCC
TTATAATACGATTGCAGATCAATTGGCTGAAATTATTGATTGTAATGCTTGTATTATTGATGGTAGTGGTATTATTCTCG
GCTATGCTATGAAGTATAAAACCAATACAGATCGTGTTGAAGAATTTTTCCAAGCTAAAAAATTACCTGATGATTATGTA
AAATCGGCCAGCCGTATTTATGATACAGAAGCCAATCTGTCGGTTGAAAATGATTTGACCATTTTTCCAATTGAATCAAA
AGATATCTATCCTGATGGCTTGACGACCATTGCTCCCATCTATGGCGGCGGTATGCGTCTTGGTTCTCTTATTATCTGGC
GTAATGATAAAGAATTCAATGATGACGATTTGATTCTAATTGAGATTTCTTCTACTGTTGTTGGAATTCAATTATTGAAC
TTGCAGACAGAAAATCTTGAAGAAACAATTCGTAAGCAGACTGCTATTAATATGGCGATTAATACCTTGTCTTATTCAGA
AATGAAAGCTGTCGCAGCTATTCTCAATGAATTAGATGGCAATGAAGGTCGCTTGACCGCATCGGTTATTGCTGATCGTA
TCGGTATTACACGTAGCGTGATTGTTAATGCTCTTAGAAAGTTAGAAAGTGCCGGTATTATTGAAAGTCGTTCCTTAGGT
ATGAAAGGTACTTATCTCAAAGTTATTAATGAAGGTATTTTTGATAAATTAAAGGACTATAGTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59388

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.37

98.467

0.644
  codY Bacillus subtilis subsp. subtilis str. 168

48.047

98.084

0.471