Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | FP512_RS01135 | Genome accession | NZ_CP042002 |
| Coordinates | 190751..191725 (+) | Length | 324 a.a. |
| NCBI ID | WP_001008574.1 | Uniprot ID | A0AAV3JGK6 |
| Organism | Streptococcus agalactiae strain GBS30 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 190966..241524 | 190751..191725 | flank | -759 |
Gene organization within MGE regions
Location: 190751..241524
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FP512_RS01135 (FP512_01150) | comYH | 190751..191725 (+) | 975 | WP_001008574.1 | class I SAM-dependent methyltransferase | Machinery gene |
| FP512_RS01140 (FP512_01155) | - | 191757..192950 (+) | 1194 | WP_000047534.1 | acetate kinase | - |
| FP512_RS01145 (FP512_01160) | - | 193102..193308 (+) | 207 | WP_000798241.1 | helix-turn-helix transcriptional regulator | - |
| FP512_RS01150 (FP512_01165) | - | 193367..193504 (+) | 138 | WP_001865900.1 | hypothetical protein | - |
| FP512_RS01155 (FP512_01170) | - | 193545..194000 (+) | 456 | WP_000905673.1 | hypothetical protein | - |
| FP512_RS01160 (FP512_01175) | - | 194069..194734 (+) | 666 | WP_000008113.1 | CPBP family intramembrane glutamic endopeptidase | - |
| FP512_RS01165 (FP512_01180) | proC | 194755..195525 (-) | 771 | WP_001865901.1 | pyrroline-5-carboxylate reductase | - |
| FP512_RS01170 (FP512_01185) | pepA | 195595..196662 (-) | 1068 | WP_001281323.1 | glutamyl aminopeptidase | - |
| FP512_RS01175 (FP512_01190) | - | 196847..197086 (-) | 240 | WP_000660180.1 | hypothetical protein | - |
| FP512_RS01180 (FP512_01195) | - | 197247..197531 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| FP512_RS01185 (FP512_01200) | - | 197528..197851 (+) | 324 | WP_000602781.1 | thioredoxin family protein | - |
| FP512_RS01190 (FP512_01205) | ytpR | 197884..198510 (+) | 627 | WP_000578328.1 | YtpR family tRNA-binding protein | - |
| FP512_RS01195 (FP512_01210) | - | 198564..199280 (-) | 717 | WP_000186185.1 | class I SAM-dependent methyltransferase | - |
| FP512_RS01200 (FP512_01215) | ssbA | 199361..199756 (+) | 396 | WP_000282447.1 | single-stranded DNA-binding protein | Machinery gene |
| FP512_RS01205 (FP512_01220) | - | 199880..200524 (+) | 645 | WP_000416612.1 | HAD family phosphatase | - |
| FP512_RS01210 (FP512_01225) | - | 200551..202296 (+) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| FP512_RS01215 (FP512_01230) | - | 202277..203017 (+) | 741 | WP_000697630.1 | LytTR family DNA-binding domain-containing protein | - |
| FP512_RS01220 (FP512_01235) | - | 203187..203642 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| FP512_RS01225 (FP512_01240) | lrgB | 203644..204372 (+) | 729 | WP_000421726.1 | antiholin-like protein LrgB | - |
| FP512_RS01230 (FP512_01250) | - | 204615..206243 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| FP512_RS01235 (FP512_01255) | - | 206356..207333 (+) | 978 | WP_000680645.1 | ABC transporter permease | - |
| FP512_RS01240 (FP512_01260) | - | 207330..208151 (+) | 822 | WP_000603397.1 | ABC transporter permease | - |
| FP512_RS01245 (FP512_01265) | - | 208163..208966 (+) | 804 | WP_000140984.1 | ABC transporter ATP-binding protein | - |
| FP512_RS01250 (FP512_01270) | - | 208950..209576 (+) | 627 | WP_000171311.1 | ABC transporter ATP-binding protein | - |
| FP512_RS01255 (FP512_01275) | treP | 209859..211889 (+) | 2031 | WP_000434616.1 | PTS system trehalose-specific EIIBC component | - |
| FP512_RS01260 (FP512_01280) | treC | 212111..213736 (+) | 1626 | WP_000151017.1 | alpha,alpha-phosphotrehalase | - |
| FP512_RS01265 (FP512_01285) | - | 213952..215988 (+) | 2037 | WP_000228180.1 | BglG family transcription antiterminator | - |
| FP512_RS01270 (FP512_01290) | - | 215991..216275 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| FP512_RS01275 (FP512_01295) | - | 216288..217643 (+) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| FP512_RS01280 (FP512_01300) | - | 217646..218503 (+) | 858 | WP_000203489.1 | transketolase | - |
| FP512_RS01285 (FP512_01305) | - | 218500..219429 (+) | 930 | WP_001203821.1 | transketolase family protein | - |
| FP512_RS01290 (FP512_01310) | - | 219538..220797 (+) | 1260 | WP_001203071.1 | ferric reductase-like transmembrane domain-containing protein | - |
| FP512_RS01295 (FP512_01315) | rpsO | 220885..221154 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| FP512_RS01300 (FP512_01320) | pnp | 221535..223664 (+) | 2130 | WP_000043850.1 | polyribonucleotide nucleotidyltransferase | - |
| FP512_RS01305 (FP512_01325) | - | 223666..224418 (+) | 753 | WP_000204782.1 | SseB family protein | - |
| FP512_RS01310 (FP512_01330) | cysE | 224427..225011 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| FP512_RS01315 (FP512_01335) | - | 225021..225203 (+) | 183 | WP_000656476.1 | lipoprotein | - |
| FP512_RS01320 (FP512_01340) | cysS | 225200..226543 (+) | 1344 | WP_000591125.1 | cysteine--tRNA ligase | - |
| FP512_RS01325 (FP512_01345) | - | 226536..226922 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| FP512_RS01330 (FP512_01350) | rlmB | 227025..227780 (+) | 756 | WP_000178026.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| FP512_RS01335 (FP512_01355) | - | 227777..228295 (+) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| FP512_RS01340 (FP512_01360) | - | 228388..229248 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| FP512_RS10475 (FP512_01370) | - | 229785..229904 (+) | 120 | Protein_209 | helix-turn-helix transcriptional regulator | - |
| FP512_RS01345 (FP512_01375) | rplM | 230129..230575 (+) | 447 | WP_001865567.1 | 50S ribosomal protein L13 | - |
| FP512_RS01350 (FP512_01380) | rpsI | 230596..230988 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| FP512_RS01355 (FP512_01390) | - | 231116..232270 (-) | 1155 | WP_000022165.1 | site-specific integrase | - |
| FP512_RS01360 (FP512_01395) | - | 232334..232924 (-) | 591 | WP_000181098.1 | helix-turn-helix domain-containing protein | - |
| FP512_RS01365 (FP512_01400) | - | 233079..233384 (+) | 306 | WP_000331954.1 | hypothetical protein | - |
| FP512_RS01370 (FP512_01405) | - | 233520..233798 (+) | 279 | WP_000134670.1 | hypothetical protein | - |
| FP512_RS01375 (FP512_01410) | - | 233809..234039 (+) | 231 | WP_000360142.1 | hypothetical protein | - |
| FP512_RS01380 (FP512_01415) | - | 234052..234378 (+) | 327 | WP_000384270.1 | replication initiator protein A | - |
| FP512_RS01385 (FP512_01420) | - | 234382..235011 (+) | 630 | WP_000591148.1 | hypothetical protein | - |
| FP512_RS01390 (FP512_01425) | - | 235324..236199 (+) | 876 | WP_000770113.1 | hypothetical protein | - |
| FP512_RS01395 (FP512_01430) | - | 236235..236669 (+) | 435 | WP_001220479.1 | hypothetical protein | - |
| FP512_RS01400 (FP512_01435) | mobV | 236985..238241 (+) | 1257 | WP_000122832.1 | MobV family relaxase | - |
| FP512_RS01405 (FP512_01440) | - | 238409..238879 (+) | 471 | WP_000130119.1 | hypothetical protein | - |
| FP512_RS01410 (FP512_01445) | - | 239184..239519 (-) | 336 | WP_000384858.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FP512_RS01415 (FP512_01450) | - | 239509..239796 (-) | 288 | WP_000255538.1 | hypothetical protein | - |
| FP512_RS01420 (FP512_01455) | - | 240199..241419 (-) | 1221 | WP_000156558.1 | site-specific integrase | - |
Sequence
Protein
Download Length: 324 a.a. Molecular weight: 37046.02 Da Isoelectric Point: 4.5224
>NTDB_id=375508 FP512_RS01135 WP_001008574.1 190751..191725(+) (comYH) [Streptococcus agalactiae strain GBS30]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
Nucleotide
Download Length: 975 bp
>NTDB_id=375508 FP512_RS01135 WP_001008574.1 190751..191725(+) (comYH) [Streptococcus agalactiae strain GBS30]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
67.302 |
97.222 |
0.654 |
| comYH | Streptococcus mutans UA140 |
67.302 |
97.222 |
0.654 |