Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   FPL13_RS05535 Genome accession   NZ_CP041968
Coordinates   1132483..1133328 (-) Length   281 a.a.
NCBI ID   WP_049513633.1    Uniprot ID   A0A7L8W5S3
Organism   Streptococcus sp. KS 6     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1127483..1138328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPL13_RS05525 (FPL13_05595) - 1128669..1130441 (-) 1773 Protein_1093 ABC transporter ATP-binding protein -
  FPL13_RS05530 (FPL13_05600) - 1130454..1132193 (-) 1740 WP_049513631.1 ABC transporter ATP-binding protein -
  FPL13_RS05535 (FPL13_05605) endA 1132483..1133328 (-) 846 WP_049513633.1 DNA/RNA non-specific endonuclease Machinery gene
  FPL13_RS05540 (FPL13_05610) - 1133427..1133603 (-) 177 WP_041784006.1 DNA-directed RNA polymerase subunit beta -
  FPL13_RS05545 (FPL13_05615) murA 1133596..1134876 (-) 1281 WP_049513635.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  FPL13_RS05550 (FPL13_05620) - 1134915..1135145 (-) 231 WP_018543445.1 DUF1146 family protein -
  FPL13_RS05555 (FPL13_05625) - 1135250..1135669 (-) 420 WP_003028068.1 F0F1 ATP synthase subunit epsilon -
  FPL13_RS05560 (FPL13_05630) atpD 1135680..1137086 (-) 1407 WP_003025268.1 F0F1 ATP synthase subunit beta -
  FPL13_RS05565 (FPL13_05635) - 1137121..1137999 (-) 879 WP_049513637.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30541.25 Da        Isoelectric Point: 10.4621

>NTDB_id=375008 FPL13_RS05535 WP_049513633.1 1132483..1133328(-) (endA) [Streptococcus sp. KS 6]
MARKKSNQKVAQSVAGLVIALVLALGGYSFSNHHGSTKPSDSTAINRSIRTNHAAPSQELAQSVLTESVKRQLKGKIEWN
GAGAFTINENKATLDAKVASVPYADNKTKLVRGQTVPTVANALLSKATRQYKNREETGNGSTAWTPAGWHQVKHLSGEYN
HAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANTSHSTGQNFYETKVRKALDKNKRVRYRVTLIYANEQDLV
PVGSHIEAKSSDSSLEMNVFVPNVQTGLRLNYQTGEVTVTN

Nucleotide


Download         Length: 846 bp        

>NTDB_id=375008 FPL13_RS05535 WP_049513633.1 1132483..1133328(-) (endA) [Streptococcus sp. KS 6]
ATGGCGAGAAAGAAATCCAATCAGAAAGTAGCACAAAGTGTAGCTGGTCTGGTTATAGCACTGGTTCTTGCGCTGGGAGG
TTATTCTTTTAGCAATCATCATGGTAGTACGAAGCCTTCTGACAGCACTGCTATTAATCGAAGTATTCGGACGAATCATG
CAGCACCCAGTCAAGAATTAGCACAGAGTGTTTTGACAGAGTCCGTTAAACGGCAACTCAAAGGAAAGATTGAATGGAAT
GGGGCAGGAGCCTTCACAATCAATGAAAATAAAGCAACATTGGATGCTAAAGTTGCAAGCGTTCCTTATGCGGATAATAA
GACTAAACTCGTCCGAGGTCAGACCGTTCCGACGGTTGCAAATGCTCTTTTGTCTAAAGCCACTCGTCAGTATAAGAATC
GTGAAGAAACGGGAAACGGCTCCACGGCTTGGACACCTGCTGGCTGGCATCAAGTCAAGCATTTATCGGGTGAATACAAT
CATGCGGTTGACCGAGGACATTTGTTGGGTTATGCTTTGATTGGTAACTTGAAAGGCTTTGATGCTTCGACCAGCAACCC
GAAAAATATAGCTGTGCAAACAGCTTGGGCTAATCAAGCAAATACTAGTCATTCTACGGGTCAAAATTTCTATGAAACAA
AGGTTCGCAAGGCACTAGACAAGAATAAACGAGTTCGGTATCGGGTGACTTTGATTTATGCTAATGAACAGGATTTAGTG
CCAGTTGGTTCGCATATTGAAGCTAAATCAAGCGATAGTAGCTTGGAAATGAATGTCTTTGTTCCCAACGTACAGACAGG
ACTTCGGCTAAATTATCAAACAGGAGAAGTGACCGTTACCAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(84-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W5S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

77.434

80.427

0.623
  endA Streptococcus pneumoniae D39

77.434

80.427

0.623
  endA Streptococcus pneumoniae R6

77.434

80.427

0.623
  endA Streptococcus pneumoniae TIGR4

77.434

80.427

0.623

Multiple sequence alignment