Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   G8B37_RS01705 Genome accession   NZ_CP049695
Coordinates   322334..324673 (+) Length   779 a.a.
NCBI ID   WP_021299031.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain ABC76     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 317334..329673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G8B37_RS01685 (G8B37_01690) lepB 319666..320259 (-) 594 WP_021299037.1 signal peptidase I -
  G8B37_RS01690 (G8B37_01695) rnhC 320270..321172 (-) 903 WP_011528946.1 ribonuclease HIII -
  G8B37_RS01695 (G8B37_01700) - 321329..321637 (+) 309 WP_002993251.1 hypothetical protein -
  G8B37_RS01700 (G8B37_01705) - 321640..322185 (+) 546 WP_002983087.1 CvpA family protein -
  G8B37_RS01705 (G8B37_01710) mutS/mutS2 322334..324673 (+) 2340 WP_021299031.1 endonuclease MutS2 Machinery gene
  G8B37_RS01710 (G8B37_01715) - 324677..325177 (+) 501 WP_021299043.1 phosphatase PAP2 family protein -
  G8B37_RS01715 (G8B37_01720) trxA 325240..325572 (+) 333 WP_257577416.1 thioredoxin -
  G8B37_RS01720 (G8B37_01725) - 325624..326211 (-) 588 WP_011528942.1 helix-turn-helix domain-containing protein -
  G8B37_RS01725 (G8B37_01730) mutY 326388..327542 (-) 1155 WP_002988276.1 A/G-specific adenine glycosylase -
  G8B37_RS01730 (G8B37_01735) - 327710..328003 (+) 294 WP_002983113.1 hypothetical protein -
  G8B37_RS01735 (G8B37_01740) rpsF 328176..328466 (+) 291 WP_002983117.1 30S ribosomal protein S6 -
  G8B37_RS01740 (G8B37_01745) ssb 328488..328979 (+) 492 WP_002983122.1 single-stranded DNA-binding protein Machinery gene
  G8B37_RS01745 (G8B37_01750) rpsR 329143..329382 (+) 240 WP_002983142.1 30S ribosomal protein S18 -

Sequence

Protein


Download         Length: 779 a.a.        Molecular weight: 87795.07 Da        Isoelectric Point: 6.6550

>NTDB_id=374956 G8B37_RS01705 WP_021299031.1 322334..324673(+) (mutS/mutS2) [Streptococcus pyogenes strain ABC76]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPKLERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHTFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
RNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEAAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide


Download         Length: 2340 bp        

>NTDB_id=374956 G8B37_RS01705 WP_021299031.1 322334..324673(+) (mutS/mutS2) [Streptococcus pyogenes strain ABC76]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
ACAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAAAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAGAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACACATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCAACGATACCTAAGATCTCTGATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTTTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CGCAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCTATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAAACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGTCCTACGTATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAATCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGCCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCACCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTAGCCTCGTTAGAGTTCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGCAGCAATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGTATTGGTACAGGCGTTATTCGTGAGGG
AGTGACAAAATATCTTCGTCGTAATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGTGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(704-778)

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-669)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.633

100

0.412