Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   G8B43_RS02240 Genome accession   NZ_CP049689
Coordinates   419897..420679 (+) Length   260 a.a.
NCBI ID   WP_002992569.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain ABC221     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 414897..425679
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G8B43_RS02220 (G8B43_02225) - 415236..416201 (-) 966 WP_011528916.1 asparaginase -
  G8B43_RS02225 (G8B43_02230) - 416273..417661 (+) 1389 WP_010922607.1 Cof-type HAD-IIB family hydrolase -
  G8B43_RS02230 (G8B43_02235) - 417783..418235 (-) 453 WP_002983265.1 universal stress protein -
  G8B43_RS02235 (G8B43_02240) - 418466..419680 (+) 1215 WP_011528914.1 pyridoxal phosphate-dependent aminotransferase -
  G8B43_RS02240 (G8B43_02245) codY 419897..420679 (+) 783 WP_002992569.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  G8B43_RS02245 (G8B43_02250) - 420826..421380 (+) 555 WP_002988559.1 cysteine hydrolase family protein -
  G8B43_RS09945 (G8B43_02255) - 421839..422163 (+) 325 Protein_393 putative PEP-binding protein -
  G8B43_RS02255 (G8B43_02260) gatC 422395..422697 (+) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  G8B43_RS02260 (G8B43_02265) gatA 422697..424163 (+) 1467 WP_011528911.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  G8B43_RS02265 (G8B43_02270) gatB 424163..425602 (+) 1440 WP_011528910.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28634.75 Da        Isoelectric Point: 4.5065

>NTDB_id=374380 G8B43_RS02240 WP_002992569.1 419897..420679(+) (codY) [Streptococcus pyogenes strain ABC221]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDDEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=374380 G8B43_RS02240 WP_002992569.1 419897..420679(+) (codY) [Streptococcus pyogenes strain ABC221]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACGATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(202-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.765

98.077

0.508